Biphenyl-4,4'-diol

4,4'-Dihydroxybiphenyl

HCID 7112CAS 92-88-6

Grundinformationen

Standard-SMILES
Oc1ccc(-c2ccc(O)cc2)cc1
InChIKey
VCCBEIPGXKNHFW-UHFFFAOYSA-N
Summenformel
C12H10O2
Durchschnittliche Molmasse
186,21 g/mol
Monoisotopische Masse
186,06807956

Namen und Bezeichner

Bevorzugter Name
4,4'-Dihydroxybiphenyl
IUPAC
4-(4-hydroxyphenyl)phenol
Lokaler Name
Biphenyl-4,4'-diol
Englischer Name
4,4'-Biphenol
Summenformel
C12H10O2
Molmasse
186.21

Namen und Synonyme

4,4'-Dihydroxybiphenyl92-88-64,4'-BIPHENOL4,4'-Biphenyldiol[1,1'-Biphenyl]-4,4'-diolBiphenyl-4,4'-diolp,p'-Biphenolp,p'-Diphenol4,4'-dihydroxydiphenylAntioxidant DOD4,4'-Dioxydiphenyl4,4'-Bisphenol
Weitere Namen anzeigen
PPDPBIPHENOLDOD(1R,2R)-Cyclohexane-1,2-diolBIPHENOL SUBL5
p,p'-DihydroxybiphenylASM DOD(1,1'-Biphenyl)-4,4'-diolDihydroxybiphenylDTXSID1029120NSC-8711DTXCID709120GM-W06

Datenbank-Bezeichner

CAS
92-88-6
PubChem CID
7112
DTXSID
DTXSID1029120
ChEMBL
CHEMBL76398
ChEBI
CHEBI:34367
UNII
R8994A0904
EC Number
202-200-5
Nikkaji
J45.978J

Eigenschaften

Berechnete Struktureigenschaften

XLogP
3,6
Polarare Oberfläche (TPSA)
40,5 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
1
Schwere Atome
14

Experimentelle und physikochemische Eigenschaften

Vapor Pressure0.00000079 [mmHg]
Physical Description · 2 Einträge

Dry Powder; Other Solid

Off-white, light beige, or light gray odorless powder; [Acros Organics MSDS]

Kovats Retention Index · 2 Einträge

1979

2046

Physikochemische Eigenschaften

Schmelzpunkt
280 · 280-282 °C(lit.)
Siedepunkt
280.69 °C · 280.69°C (rough estimate)
Dichte
1.22 · 1.22
Dampfdruck
0 Pa · 0Pa at 25℃
Brechungsindex
1.601 · 1.6010 (estimate)
storage temp.
Sealed in dry,Room Temperature

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.5% (1 of 211) of reports.

Warning

H312 (44.1%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (26.1%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (55.9%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (25.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (25.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H411 (18.5%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard];H412 (55.5%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 211 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 211 reports by companies.;There are 14 notifications provided by 210 of 211 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: [1,1'-Biphenyl]-4,4'-diol

[1,1'-Biphenyl]-4,4'-diol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of [1,1'-Biphenyl]-4,4'-diol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15910;Status: Active Update: 07-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22776

Hazards Summary · 1 Eintrag

Showed estrogenic activity in Saccharomyces cerevisiae hER in vivo assays; [EPA - TSCATS] Abnormal urinalysis, reversible gross and histopathological liver changes in males, and no evidence of reproductive or developmental toxicity observed in oral study of rats; [JECDB] May cause skin sensitization; [ECHA REACH Registrations] An irritant; Harmful by skin absorption; [Acros Organics MSDS] See Biphenyl.

Hazard Classes and Categories · 3 Einträge

Acute Tox. 4 (44.1%);Skin Irrit. 2 (26.1%);Skin Sens. 1 (55.9%);Eye Irrit. 2 (25.6%);STOT SE 3 (25.1%);Aquatic Chronic 2 (18.5%);Aquatic Chronic 3 (55.5%)

Acute toxicity (Dermal) - Category 4;Germ cell mutagenicity - Category 2;Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 2

Skin sensitization - Category 1;Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 2

Toxikologische Informationen

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

Regulatorische Informationen

Regulatory Information · 3 Einträge

Chemical: [1,1'-Biphenyl]-4,4'-diol

[1,1'-Biphenyl]-4,4'-diol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of [1,1'-Biphenyl]-4,4'-diol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 30-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15910;Status: Active Update: 07-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22776

Sicherheitsdaten

wgk
2
tsca
TSCA listed
ridadr
3077
hs_code
29061900
RTECS-Nr.
DV4725000
risk_code
21-36/37/38-37/38/68-36

Chemie und Industrie

Verwendung und Herstellung

UsesUsed to make plastics and as a laboratory reagent; [ECHA REACH Registrations]
U.S. Production2023: 10,000,000 - <25,000,000 lb;2022: 10,000,000 - <25,000,000 lb;2021: 10,000,000 - <25,000,000 lb;2020: 10,000,000 - <25,000,000 lb
Consumer UsesMonomers
Industry UsesMonomers;Intermediate
General Manufacturing Information · 2 Einträge

All Other Chemical Product and Preparation Manufacturing;Plastics Material and Resin Manufacturing

[1,1'-Biphenyl]-4,4'-diol: ACTIVE

Anwendungen · 1 Eintrag

Verwenden4,4'-biphenol be used intermediate liquid crystal polymers raw materials. Synthetic polymers, due to its excellent heat resistance, it is used as polyester, urethane modified monomer, polycarbonate, polysulfone, and epoxy resin, for the manufacture of an excellent engineering plastics and composite materials. Antioxidant antioxidants for rubber and plastics. Dye intermediates or petroleum products stabilizer.

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A member of the class of hydroxybiphenyls that is biphenyl with hydroxy groups at positions 4 and 4'.

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