Identifikatoren & physikalische Daten
| CAS No. | 75-12-7 |
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| Summenformel | CH3NO |
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| Durchschnittliche Molmasse | 45,041 g/mol |
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| Monoisotopische Masse | 45,02146372 g/mol |
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| SMILES | NC=O |
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| InChIKey | ZHNUHDYFZUAESO-UHFFFAOYSA-N |
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| PubChem CID | 713 |
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| ChEMBL | CHEMBL266160 |
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| ChEBI | CHEBI:16397 |
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| EC No. | 200-842-0 |
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| DTXSID | DTXSID8025337 |
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Chemische & physikalische Eigenschaften
| XLogP | -0,8 |
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| Polarare Oberfläche (TPSA) | 43,1 |
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| H-Brücken-Donoren | 1 |
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| H-Brücken-Akzeptoren | 1 |
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| Frei drehbare Bindungen | 0 |
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| Schwere Atome | 3 |
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| Formalladung | 0 |
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| Komplexität | 12,3 |
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| Solvents | Solvents -> Amides (<C10) |
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| pH | 7.1 (0.5 molar aqueous soln) |
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| LogP (Verteilungskoeffizient) | log Kow= -1.51 |
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| Geruch | Faint ammonia odorOdorless |
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| Dichte | 1.1334 at 68 °F (USCG, 1999) - Denser than waterwill sink1.1334 @ 20 °C/4 °CRelative density (water = 1): 1.131.134 @ 20°C1.1334 g/cm3 |
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| Viscosity | nX10+5 @ 20 °C= 4320@ 30 °C= 2926 |
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| Color/Form | Slightly viscous, colorless liquidOily liquid |
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| Löslichkeit | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)Sol in alcohol and acetoneMiscible with methanol, phenol, dioxane, acetic acid, ethylene glycol, USP glycerol.Insoluble in ethanolvery soluble in ethyl ethermiscible in chloroform, petroleum ether.In water, 1.0X10+6 mg/l @ 25 °C.1000.0 mg/mL |
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| Corrosivity | Copper, brass and even lead are attacked. |
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| Flammpunkt | 310 °F (NTP, 1992)310 °F (OPEN CUP)120 °C c.c.310 °F (open-cup)(oc) 310 °F |
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| Endocrine Disruptors | Potential endocrine disrupting compound |
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| Siedepunkt | 410 °F at 760 mmHg (decomposes) (NTP, 1992)210.5 °C @ 760 mm HgBP: 200-212 °C with partial decomposition beginning approximately 180 °C411 °F (decomposes)220 °C @760 [mm Hg] |
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| Schmelzpunkt | 2.55 °C |
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| pKa (Säurekonstante) | 16.50±0.50(Predicted) |
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Sicherheit & Vorschriften
| GHS-Einstufung | DangerH360D ***: May damage the unborn child [Danger Reproductive toxicity]P203, P280, P318, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.3% (1 of 388) of reports.H351 (52.1%): Suspected of causing cancer [Warning Carcinogenicity] |
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| Regulatorische Informationen | Chemical: FormamideHazard Traits - Reproductive ToxicityRegulation (EC) No 1831/2003 (amended)Formamide is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Formamide are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 23-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14929Substance: Formamide |
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| Weitere Sicherheitsinformationen | IMAP assessments - Formamide: Environment tier I assessment |
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| Brandgefahren | Special Hazards of Combustion Products: Toxic fumes emitted on decomposition (carbon monoxide and ammonia), beginning at 180 - 210 °C.Combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
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| Brandpotenzial | Combustible when exposed to heat or flame. |
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| Gesundheitsgefahren | INHALATION: A moderate irritant to mucous membranes. EYES: Moderately irritating to the eyes. SKIN: A mild to moderate irritant to the skin. (USCG, 1999) |
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| Gefahrenübersicht | Subchronic studies of rats exposed at 1500 ppm show decreased weight gain, kidney injury, and suppression of platelets and lymphocytes. By analogy with dimethylformamide, formamide is a suspected liver toxin. No signs of toxicity were detected in rats exposed 6 hours/day for 10 days at approximately 100 ppm of formamide vapor (equivalent to air saturated with formamide at room temperature). [ACGIH] A skin and eye irritantInhalation of high concentrations may cause CNS effects[ICSC] |
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| FDA-Anforderungen | Formamide is an indirect food additive for use only as a component of adhesives. |
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