(3alpha,5beta,12alpha)-3,12-Dihydroxy(2,2,4,4-~2~H_4_)cholan-24-oic acid
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
112076-61-6- Standard-SMILES
[2H]C1([2H])C[C@@]2(C)[C@H](CC[C@@H]3[C@@H]2C[C@H](O)[C@]2(C)[C@@H]([C@H](C)CCC(=O)O)CC[C@@H]32)C([2H])([2H])[C@@H]1O- InChIKey
KXGVEGMKQFWNSR-FCSCGBJGSA-N- Summenformel
- C24H40O4
- Durchschnittliche Molmasse
- 396,6044 g/mol
- Monoisotopische Masse
- 396,31776674
Namen und Bezeichner
- Bevorzugter Name
- (3alpha,5beta,12alpha)-3,12-Dihydroxy(2,2,4,4-~2~H_4_)cholan-24-oic acid
- IUPAC
- 3alpha,12alpha-Dihydroxy(2,2,4,4-~2~H_4_)-5beta-cholan-24-oic acid
- Englischer Name
- Deoxycholic-2,2,4,4-d4 acid
- Summenformel
- C24H40O4
- Molmasse
- 392.58
Namen und Synonyme
Deoxycholic acid-DDeoxycholic-d4 AcidD4-Deoxycholic Acid2H4]-Deoxycholic acidDeoxycholic-2,2,4,4-d4 acidDeoxycholic acid-2,2,4,4-d4Deoxycholic Acid-D4 (Standard)Deoxycholic Acid-[d4] (Solution)Deoxycholic Acid-[d4] in MethanolDeoxycholic acid (2,2,4,4-D?, 98%)
Datenbank-Bezeichner
- CAS
112076-61-6- PubChem CID
- 71309027
- DTXSID
DTXSID90745736- ChEBI
CHEBI:192782- EC Number
- 693-876-4
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 171 · 171-174 °C
- Flammpunkt
- 9 ℃ · 9℃
- storage temp.
- -20 °C · -20°C
- Löslichkeit
- DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChIKey
- KXGVEGMKQFWNSR-FCSCGBJGSA-N
- SMILES
- [H][C@@]12[C@]([C@](CC([2H])([2H])[C@@H](O)C3([2H])[2H])(C)[C@]3([H])CC2)([H])C[C@H](O)[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O
- CAS Number Unlabeled
- 83 · 83-44-3
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- ridadr
- UN1230 - class 3 - PG 2 - Methanol, solution
- risk_code
- 22-36/37/38
- hazard_code
- Xn
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Acute Tox. 4 Oral
Chemie und Industrie
Anwendungen
BeschreibungDeoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.
VerwendenDeoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound.
Anbieter35 Anbieter
盐城通铭生物科技有限公司15195160625 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
Aladdin Scientific[email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
梯希爱（上海）化工贸易有限公司
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…