coenzyme a, s-(hydrogen butanedioate), sodium salt

BeschreibungSuccinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle. It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis. Succinyl-CoA deficiency, caused by vitamin B12 deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.

VerwendenSuccinyl coenzyme A sodium salt has been used: for the nonenzymatic succinylation of lysine in vitro, as a substrate for adipic acid biosynthesis in recombinant E. coli in isocitrate dehydrogenase (ICDH)treatment for the succinylation of proteinsas a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)