HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(2-Aminoethyl)pyrocatechinhydrobromid
usafel-47 · Dopamine=PIH · Dopamine USP/EP/BP · DOPAMINE HYDROBROMIDE · 4-(aminoethyl)catechol · 4-(2-aminoethyl)-pyrocatecho · 4-(2-aminoethyl)pyrocatechol · 3,4-dihydroxyphenylethylamine
Identifikatoren & physikalische Daten
| CAS No. | 645-31-8 |
|---|---|
| Summenformel | C8H12BrNO2 |
| Durchschnittliche Molmasse | 234,09 g/mol |
| Monoisotopische Masse | 233,00514072 g/mol |
| SMILES | Br.NCCc1ccc(O)c(O)c1 |
| InChIKey | SGRSNYSOAPBTJP-UHFFFAOYSA-N |
| PubChem CID | 71564 |
| EC No. | 211-436-8 |
| DTXSID | DTXSID20214748 |
| Lokaler Name | 4-(2-Aminoethyl)pyrocatechinhydrobromid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 66,5 |
|---|---|
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 119 |
| Schmelzpunkt | 218-220 °C(lit.) |
| Aggregatzustand | solid |
| InChI | 1S/C8H11NO2.BrH/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 |
| InChIKey | SGRSNYSOAPBTJP-UHFFFAOYSA-N |
| SMILES | Br.NCCc1ccc(O)c(O)c1 |
| CAS Datenbank | 645-31-8(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 4.9% (2 of 41) of reports.WarningH315 (95.1%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 04-07-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19950 |
| Hazard Classes and Categories | Skin Irrit. 2 (95.1%) |
| Wassergefährdungsklasse (WGK) | 3 |
| RTECS-Nr. | SH2290150 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-37/39-37 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
3-Hydroxytyramine hydrobromide was used in the preparation of dopamine standards to measure the dopamine release and uptake in striatal brain slices from R6/1 HD model mice by fast-scan cyclic voltammetry. It was employed as internal standard in the determination of catecholamines in biological tissues by liquid chromatography.