2-Hydroxy-gamma-butyrolactone, (2R)-

HCID 7157070

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Grundinformationen

CAS: 56881-90-4
Standard-SMILES: O=C1OCC[C@H]1O
InChIKey: FWIBCWKHNZBDLS-GSVOUGTGSA-N
Summenformel: C4H6O3
Durchschnittliche Molmasse: 102,09 g/mol

Namen und Bezeichner

Bevorzugter Name: 2-Hydroxy-gamma-butyrolactone, (2R)-
IUPAC: (3R)-3-hydroxyoxolan-2-one
Englischer Name: (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Summenformel: C4H6O3
Molmasse: 102.09

Namen und Synonyme

56881-90-4(R)-3-Hydroxydihydrofuran-2(3H)-one(R)-(+)-alpha-Hydroxy-gamma-butyrolactone(3R)-3-hydroxyoxolan-2-one(R)-alpha-hydroxy-gamma-butyrolactoneSG03T0K3QH2(3H)-Furanone, dihydro-3-hydroxy-, (3R)-(3R)-Dihydro-3-hydroxy-2(3H)-furanone2-Hydroxy-gamma-butyrolactone, (+)-2-Hydroxy-gamma-butyrolactone, (2R)-2-HYDROXY-.GAMMA.-BUTYROLACTONE, (+)-2-HYDROXY-.GAMMA.-BUTYROLACTONE, (2R)-

Weitere Namen anzeigen

-Hydroxy-γRARECHEM AK HZ 0027(R)-2-HYDROXYBUTYROLACTONE3-deoxy-L-glycero-tetronolactone(R)-2-HYDROXY-GAMMA-BUTYROLACTONE(R)-(+)-α-Hydroxy-γ-butyrolactone(R)-(+)-α-Hydroxy-γ-butyrolactone(3R)-3-hydroxytetrahydrofuran-2-one(R)-(+)-α-Hydroxy-γ-butyrolactone>

(R)-.ALPHA.-HYDROXY-.GAMMA.-BUTYROLACTONE(R)-(+)-.ALPHA.-HYDROXY-.GAMMA.-BUTYROLACTONERefChem:473334894-399-6MFCD00211246(R)-(+)-|A-Hydroxy-|A-butyrolactoneUNII-SG03T0K3QH(3R)-3-hydroxydihydro-2(3H)-furanone

Datenbank-Bezeichner

CAS: 56881-90-4
PubChem CID: 7157070
UNII: SG03T0K3QH
EC Number: 894-399-6
Nikkaji: J517.045A

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -0,4
Polarare Oberfläche (TPSA): 46,5 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 3
Frei drehbare Bindungen: 0
Schwere Atome: 7
Formalladung: 0
Komplexität: 88,9

Physikochemische Eigenschaften

Siedepunkt: 133 °C/10 · 133 °C/10 mmHg (lit.)
Dichte: 1.309 g/mL · 1.309 g/mL at 25 °C (lit.)
Brechungsindex: 20 · n20/D 1.467(lit.)
Flammpunkt: 230 °F · >230 °F
storage temp.: 2 · 2-8°C
Aggregatzustand: clear liquid
pka: 13.07 · 13.07±0.20(Predicted)
Wichte: 1.32 · 1.32
Farbe: Colorless to Light yellow
BRN: 80588 · 80588
InChI: 1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1
InChIKey: FWIBCWKHNZBDLS-GSVOUGTGSA-N
SMILES: O[C@@H]1CCOC1=O
CAS Datenbank: 56881 · 56881-90-4(CAS DataBase Reference)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Gefahrenhinweise

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheitsdaten

wgk: 3
hs_code: 2932209090
Speicherklasse: 10 - Combustible liquids

Chemie und Industrie

Anwendungen · 1 Eintrag

Verwenden(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize: δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions. Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents. Botryolide B via esterification and ring-closing metathesis reaction.Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.