Azidocillin Potassium
Grundinformationen
- CAS
22647-32-1- Standard-SMILES
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N=[N+]=[N-])c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[K+]- InChIKey
BNCKHYBJSCFJOI-YWUHCJSESA-M- Summenformel
- C16H16KN5O4S
- Durchschnittliche Molmasse
- 413,5 g/mol
- Monoisotopische Masse
- 413,05600667
Überblick
Azidocillin Potassium is the potassium salt of a narrow-spectrum, semisynthetic penicillin derivative with antibacterial activity. Azidocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
Namen und Bezeichner
- Bevorzugter Name
- Azidocillin Potassium
- IUPAC
- potassium (2S,5R,6R)-6-[[(2R)-2-azido-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Namen und Synonyme
Azidocillin potassium22647-32-1UNII-7932098147DTXSID40177189AZIDOCILLIN POTASSIUM [WHO-DD]D-(-)-.ALPHA.-AZIDOBENZYLPENICILLIN POTASSIUM SALT4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-((AZIDOPHENYLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOPOTASSIUM SALT, (2S-(2.ALPHA.,5.ALPHA.,6.BETA.(S*)))-RefChem:116090DTXCID7099680D-(-)-ALPHA-AZIDOBENZYLPENICILLIN POTASSIUM SALT4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-((AZIDOPHENYLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, MONOPOTASSIUM SALT, (2S-(2ALPHA,5ALPHA,6BETA(S*)))-4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid,6-((Azidophenylacetyl)Amino)-3,3-Dimethyl-7-Oxo-, Monopotassium Salt, (2s-(2Alpha,5Alpha,6Beta(S*)))-
Weitere Namen anzeigen
7932098147Q27231287Potassium (2S,5R,6R)-6-((R)-2-azido-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatePotassium (2S,5R,6R)-6-{[(2R)-2-azido-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 129 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 27
- Formalladung
- 0
- Komplexität
- 666
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