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(S)-Glycidyl Trityl Ether
(S)-2-((trityloxy)methyl)oxirane · Trityl-(s)-glycidyl ether · (S)-TRITYL GLYCIDYL ETHER · (S)-GLYCIDYL TRITYL ETHER · (S)-GlycidylTritylEther>(S)-(-)-GLYCIDYL TRITYL ETHER · (S)-(-)-TRITYL GLYCIDYL ETHER · Triphenylmethyl glycidyl ether · (2S) 2 (TRITYLOXYMETHYL)OXIRANE
Identifikatoren & physikalische Daten
| CAS No. | 129940-50-7 |
|---|---|
| Summenformel | C22H20O2 |
| Durchschnittliche Molmasse | 316,4 g/mol |
| Monoisotopische Masse | 316,14632988 g/mol |
| SMILES | c1ccc(C(OC[C@@H]2CO2)(c2ccccc2)c2ccccc2)cc1 |
| InChIKey | XFSXUCMYFWZRAF-NRFANRHFSA-N |
| PubChem CID | 7168113 |
| EC No. | 603-374-9 |
| DTXSID | DTXSID50428235 |
Chemische & physikalische Eigenschaften
| XLogP | 4,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 21,8 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 6 |
| Schwere Atome | 24 |
| Formalladung | 0 |
| Komplexität | 330 |
| Schmelzpunkt | 99-102 °C (lit.) |
| Siedepunkt | 438.8±40.0 °C(Predicted) |
| Dichte | 1.146±0.06 g/cm3(Predicted) |
| Brechungsindex | -11 ° (C=1, CHCl3) |
| Lagerbedingungen | under inert gas (nitrogen or Argon) at 2-8°C |
| Löslichkeit | almost transparency in hot Methanol |
| Aggregatzustand | powder to crystal |
| Farbe | White to Light yellow |
| InChI | InChI=1S/C22H20O2/c1-4-10-18(11-5-1)22(24-17-21-16-23-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17H2/t21-/m0/s1 |
| InChIKey | XFSXUCMYFWZRAF-NRFANRHFSA-N |
| SMILES | O1C[C@H]1COC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| CAS Datenbank | 129940-50-7(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29109000 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 37/39-26 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
(S)-(-)-Glycidyl trityl ether may be used to prepare N-(p-alkoxy)benzoyl-2-methylindole-4-acetic acid analogs, which are potent prostaglandin D2 (PGD2) receptor antagonists. It may also be used as a starting material in the multi-step synthesis of (-)-actisonitrile.