N2-[(1R)-1-carboxy-3-(2H5)phenylpropyl]-L-lysyl-D-proline
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Grundinformationen
- CAS
1356905-39-9- Standard-SMILES
[2H]c1c([2H])c([2H])c(CC[C@@H](N[C@@H](CCCCN)C(=O)N2CCC[C@@H]2C(=O)O)C(=O)O)c([2H])c1[2H]- InChIKey
RLAWWYSOJDYHDC-XIPFODBISA-N- Summenformel
- C21H31N3O5
- Durchschnittliche Molmasse
- 410,5255 g/mol
- Monoisotopische Masse
- 410,25775482
Namen und Bezeichner
- Bevorzugter Name
- N2-[(1R)-1-carboxy-3-(2H5)phenylpropyl]-L-lysyl-D-proline
- Englischer Name
- (S)Lisinopril-D5
- Summenformel
- C21H26D5N3O5
- Molmasse
- 410.52
Namen und Synonyme
[2H5]-Lisinopril(S)Lisinopril-D5[2H5]-(S)-LisinoprilRLAWWYSOJDYHDC-MMUMHYRKSA-N(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline-d5(S)-Lisinopril D5Q: What is (S)-Lisinopril D5 Q: What is the CAS Number of (S)-Lisinopril D5 Q: What is the storage condition of (S)-Lisinopril D5 Q: What are the applications of (S)-Lisinopril D5
Datenbank-Bezeichner
- CAS
1356905-39-9- PubChem CID
- 71749822
- DTXSID
DTXSID301363977
Eigenschaften
Physikochemische Eigenschaften
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- Methanol: soluble; Water: soluble
- Aggregatzustand
- A solid
- Farbe
- White to off-white
- InChIKey
- RLAWWYSOJDYHDC-MMUMHYRKSA-N
- SMILES
- C(N1CCC[C@H]1C(=O)O)(=O)[C@H](CCCCN)N[C@H](C(=O)O)CCC1C([2H])=C([2H])C([2H])=C([2H])C=1[2H]
- CAS Datenbank
- 1356905 · 1356905-39-9
Chemie und Industrie
Anwendungen
BeschreibungLisinopril-d5 is intended for use as an internal standard for the quantification of lisinopril by GC- or LC-MS. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.2 nM). It reduces the formation of endothelin-1 and increases nitric oxide in human vascular endothelial cells. Lisinopril inhibits the pressor response to angiotensin I in anesthetized rats and dogs (ID50s = 2.3 and 6.5 μg/kg in rat and dog, respectively).
Verwenden(S)Lisinopril-D5 can be Labeled , it is an orally active angiotensin-converting enzyme (ACE) inhibitor , intended for use as an internal standard for the quantification of Lisinopril by GC- or LC-mass spectrometry.
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