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Grundinformationen
- CAS
21721-92-6- Standard-SMILES
Cc1nc([N+](=O)[O-])cn1-c1ccc([N+](=O)[O-])cc1- InChIKey
NMTBSNPBIGRZBL-UHFFFAOYSA-N- Summenformel
- C10H8N4O4
- Durchschnittliche Molmasse
- 248,198 g/mol
- Monoisotopische Masse
- 248,05455474
Namen und Bezeichner
- Bevorzugter Name
- Nitrefazole
- IUPAC
- 2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole
- Lokaler Name
- Nitrefazol
- Englischer Name
- Nitrefazole
- Summenformel
- C10H8N4O4
- Molmasse
- 248.19
Namen und Synonyme
bt-985ALTIMOLEMD 15700NITREFAZOLE1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol2-methyl-4-nitro-1-(4-nitrophenyl)imidazole2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
Datenbank-Bezeichner
- CAS
21721-92-6- PubChem CID
- 71900
- DTXSID
DTXSID2048826- ChEMBL
CHEMBL1909285- ChEBI
CHEBI:135009- UNII
- VFD629099M
- EC Number
- 244-542-8
- Nikkaji
- J126.295E
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 185 · 185-187°
- storage temp.
- Refrigerator
- Löslichkeit
- Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- Farbe
- Light Yellow to Yellow
Chemie und Industrie
Anwendungen
BeschreibungNitrefazole is an inhibitor of aldehyde dehydrogenase useful in the management of alcoholism. Cited advantages over disulfiram include longer duration of action, higher specificity (no inhibition of dopamine β-hydroxylase) and fewer side effects. It is generally recognized that the efficacy of such agents with respect to permanent abstinence is low. However, temporary abstinence and/or controlled drinking may facilitate supportive psychotherapy and/or delay the onset of severe alcoholic diseases.
VerwendenNitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
Anbieter10 Anbieter
河南伊诺凯新材料有限公司15670530983 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
东阳市求索医药科技有限公司17502510579 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
成都同创源医药科技有限公司028-83379370 13880556291 · [email protected]
上海万千化工有限公司18796480002 18796480002 · [email protected]
Hefei Hirisun Pharmatech Co., Ltd+8615056975894 · [email protected]
TargetMol中国（陶术生物）
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