Epanolol
Grundinformationen
- CAS
86880-51-5- Standard-SMILES
N#Cc1ccccc1OCC(O)CNCCNC(=O)Cc1ccc(O)cc1- InChIKey
YARKMNAWFIMDKV-UHFFFAOYSA-N- Summenformel
- C20H23N3O4
- Durchschnittliche Molmasse
- 369,4 g/mol
- Monoisotopische Masse
- 369,16885622
Überblick
Epanolol is a member of acetamides.
Namen und Bezeichner
- Bevorzugter Name
- Epanolol
- IUPAC
- N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamide
- Englischer Name
- Epanolol
- Summenformel
- C20H23N3O4
- Molmasse
- 369.41
Namen und Synonyme
Epanolol86880-51-5EpanololumICI-141292ICI 141,2929KGC55KP6ADTXSID90868959Benzeneacetamide, N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxy-ICI-141,292N-(2-((3-(2-cyanophenoxy)-2-hydroxy-propyl)amino)ethyl)-2-(4-hydroxyphenyl)acetamideN-[2-[[3-(2-cyanophenoxy)-2-hydroxy-propyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamideRefChem:590903
Weitere Namen anzeigen
EponololN-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxybenzeneacetamideBenzeneacetamide, N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-hydroxy-
N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)-4-hydroxyphenylacetamideC07AB10DTXCID20817011VisacorEpanololum [Latin]ICI141292N-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-2-(4-hydroxyphenyl)acetamideVisacor;ICI141292
Datenbank-Bezeichner
- CAS
86880-51-5- PubChem CID
- 72014
- DTXSID
DTXSID90868959- ChEMBL
CHEMBL87697- ChEBI
CHEBI:4800- UNII
- 9KGC55KP6A
- Nikkaji
- J25.825C
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,9
- Polarare Oberfläche (TPSA)
- 115 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 10
- Schwere Atome
- 27
- Formalladung
- 0
- Komplexität
- 485
Experimentelle und physikochemische Eigenschaften
LogP0.92
Physikochemische Eigenschaften
- Schmelzpunkt
- 118 · 118-120°
- Siedepunkt
- 689.7 · 689.7±55.0 °C(Predicted)
- Dichte
- 1.28 · 1.28±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- Soluble in DMSO
- pka
- 9.87 · 9.87±0.15(Predicted)
Chemie und Industrie
Pharmakologische Informationen
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Anwendungen
VerwendenEpanolol is a adrenergic β-antagonist. Epanolol is used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
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