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1,2,4-Trimethylbenzol
TRIMETHYLBENZENE · PSC · pseudo · 1,2,4-trimethylbenzene (pseudocumene) · PSEUDOCUMENE · 1,2,4-trimethyl-benzen · PSI-CUMENE · PSEUDOCUMOL
Identifikatoren & physikalische Daten
| CAS No. | 95-63-6 |
|---|---|
| Summenformel | C9H12 |
| Durchschnittliche Molmasse | 120,19 g/mol |
| Monoisotopische Masse | 120,09390038 g/mol |
| SMILES | Cc1ccc(C)c(C)c1 |
| InChIKey | GWHJZXXIDMPWGX-UHFFFAOYSA-N |
| PubChem CID | 7247 |
| ChEMBL | CHEMBL1797280 |
| ChEBI | CHEBI:34039 |
| EC No. | 202-436-9 |
| DTXSID | DTXSID6021402 |
| Lokaler Name | 1,2,4-Trimethylbenzol |
Chemische & physikalische Eigenschaften
| XLogP | 3 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 86 |
| Stoffklassen | Flammable agents - 2nd degreeVolatile Organic Compound (VOC) |
| Solvents | Solvents -> Aromatic Solvents |
| Kosmetika | Cosmetics ingredient -> FragranceOther (Specify) |
| SpringerMaterials Properties | 13C nuclear magnetic resonance spectrum |
| Duftstoffe | Fragrance Ingredient (Benzene, 1,2,4-trimethyl-) -> IFRA transparency List |
| Pestizide | Pesticide -> EPA IRIS |
| LogP (Verteilungskoeffizient) | log Kow = 3.783.633.8 |
| Geruch | Distinctive, aromatic odor |
| Dichte | 0.889 (USCG, 1999) - Less dense than waterwill float0.8758 g/cu cm at 20 °C0.8718 g/cu cm at 25 °CRelative density (water = 1): 0.880.8758 @ 20°C0.876 g/mL at 20 °C(lit.) |
| Color/Form | Clear, colorless liquid |
| Löslichkeit | 0.006 % (NIOSH, 2024)Miscible with ethanol, benzene, ethyl ether, acetone, carbon tetrachloride, petroleum etherIn water, 57 mg/L at 25 °C0.057 mg/mL at 25 °CSolubility in water: very poor0.006%0.057g/lSoluble in alcohol, benzene and ether. Slightly soluble in water |
| Flammpunkt | 111 °F (USCG, 1999)44 °C112 °F (44 °C) (Closed cup)44 °C c.c.120 °F |
| Schmelzpunkt | -44 °C |
| Siedepunkt | 168 °C(lit.) |
| Dampfdichte | 4.1 (vs air) |
| Dampfdruck | 4.5 mm Hg ( 37.7 °C) |
| Brechungsindex | n20/D 1.504(lit.) |
| Lagerbedingungen | Store below +30°C. |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | >14 (Schwarzenbach et al., 1993) |
| Farbe | Clear colorless |
| Geruch | char. aromatic odor |
| Geruchsschwelle | 0.12ppm |
| Explosionsgrenze | 0.8-7%(V) |
| Spezifische Wärmekapazität | Cp(liquid): 1.79 J/(g·K), at 25℃ |
| Merck | 14,7915 |
| BRN | 1903005 |
| Henry-Konstante | 6.946, 11.202, and 15.702 at 27.0, 35.0, and 45.0 °C, respectively (dynamic headspace, Hansen et al., 1995) |
| Dielektrizitätskonstante | 2.4(16℃) |
| Stabilität | Stable. Incompatible with strong oxidizing agents. Flammable. May form explosive mixtures with air. |
| Kosmetik-Inhaltsstoffe Funktionen | SOLVENT |
| InChI | 1S/C9H12/c1-7-4-5-8(2)9(3)6-7/h4-6H,1-3H3 |
| InChIKey | GWHJZXXIDMPWGX-UHFFFAOYSA-N |
| SMILES | Cc1ccc(C)c(C)c1 |
| LogP (Verteilungskoeffizient) | 3.630 |
| Oberflächenspannung | 29.3mN/m at 298.15K |
| CAS Datenbank | 95-63-6(CAS DataBase Reference) |
| EPA chemische Informationen | 1,2,4-Trimethylbenzene (95-63-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH226: Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P273, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.4% (13 of 3204) of reports.DangerH226 (99.6%): Flammable liquid and vapor [Warning Flammable liquids] |
|---|---|
| Regulatorische Informationen | Chemical: Benzene, 1,2,4-trimethyl-Hazard Traits - Nephrotoxicity and Other Toxicity to the Urinary SystemNeurotoxicityBenzene, 1,2,4-trimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzene, 1,2,4-trimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 21-01-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13135Benzene, 1,2,4-trimethyl-: HSNO Approval: HSR001382 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | IMAP assessments - Benzene, 1,2,4-trimethyl-: Human health tier I assessment |
| DOT-Kennzeichnung | Flammable Liquid |
| Brandgefahren | Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:Flammable. Above 44 °C explosive vapour/air mixtures may be formed. |
| Brandpotenzial | MODERATE FIRE RISK.IN ABSENCE OF PRECAUTIONS, FLAMMABLE CONCN OF VAPOR MAY BE PRESENT WHERE LIQUIDS ARE USED IN SOLVENT & THINNER OPERATIONS. /TRIMETHYL BENZENE/ |
| Gesundheitsgefahren | Harmful if inhaled or swallowed. Vapor or mist is irritating to the eyes, mucous membrane and upper respiratory tract. Prolonged contact can cause dermatitis, nausea, headache, dizziness, and narcotic effect. (USCG, 1999) |
| Gefahrenübersicht | A skin, eye, and respiratory tract irritantInhalation of high concentrations can cause CNS depression[HSDB] A skin, eye, and respiratory tract irritantMay cause chemical pneumonitis after aspirationDefats the skinMay have effects on the central nervous system and blood[ICSC] Reported blood dycrasias in chronically exposed workers were probably caused by benzene present as a contaminant[ACGIH] An irritant[MSDSonline] See Trimethyl benzene isomers.The major hazards encountered in the use and handling of 1,2,4-trimethylbenzene stem from its toxicologic properties. Toxic by inhalation and dermal contact, exposure to this liquid may occur from its use as a solvent and paint thinner, and in the manufacture of dyes, perfumes, resins, pharmaceuticals, and trimellitic anhydride. Effects from exposure may include headache, fatigue, nausea, irritation of the skin, eyes, and mucous membranes, central nervous system depression, asthmatic bronchitis, chemical pneumonitis, or pulmonary edema. If contact should occur, irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes, and wash exposed skin thoroughly with soap and water. While this substance must be moderately heated before ignition will occur (autoignition temperature: 932 °F), caution should be taken to prevent its heavier-than-air vapor from accumulating to flammable concentrations (flammable limits by volume: 0.9% to 6.4%). Water spray may be used to extinguish fires involving this substance. |
| Reaktive Gruppe | Hydrocarbons, Aromatic |
| EG-Einstufung | Symbol: Xn, NR: 10-20-36/37/38-51/53S: (2)-26-61 |
| UN-Einstufung | UN Hazard Class: 3UN Pack Group: III |
| TSCA-Anforderungen | Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. 1,2,4-Trimethylbenzene is included on this list. Effective date 4/29/1983Sunset date 4/29/1993. |
| Reactivity Profile | 1,2,4-TRIMETHYLBENZENE is incompatible with the following: Oxidizers, nitric acid (NIOSH, 2024). |
| Brandbekämpfung | Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:Use alcohol-resistant foam, dry powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. |
| Erste-Hilfe-Maßnahmen | Fresh air, rest. Refer for medical attention.Rinse skin with plenty of water or shower.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Do NOT induce vomiting. Refer for medical attention . |
| Erste Hilfe | Excerpt from NIOSH Pocket Guide for 1,2,4-Trimethylbenzene:(General first aid procedures) |
| Sichere Lagerung | Fireproof. Separated from strong oxidants. Well closed. Keep in a well-ventilated room. |
| Expositionsschutz und Persönliche Schutzausrüstung | 20.0 [ppm] |
| Brandbekämpfungsverfahren | This chemical is a flammable liquid. Poisonous gases are produced in fire. Small fires: dry chemical, carbon dioxide, water spray, or alcohol-resistant foam. Large fires: water spray, fog, or alcohol foam. Move container from fire if you can do so without risk. Spray cooling water on containers that are exposed to flames until well after fire is out. For massive fire in cargo area, use unmanned hose holder or monitoring nozzlesif this is impossible, withdraw from area and let fire burn. Isolate for one-half mile in all directions if tank car or truck is involved in fire. Vapors are heavier than air and will collect in low areas. Vapors may travel long distances to ignition sources and flashback. Vapors in confined areas may explode when exposed to fire. Containers may explode in fire. Storage containers and parts of containers may rocket great distances, in many directions. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors, or shows any signs of deforming), withdraw immediately to a secure position. If employees are expected to fight fires, they must be trained and equipped in OSHA 1910.156. /Trimethyl benzenes/ |
| Lagerbedingungen | Prior to working with this chemical you should be trained on its proper handling and storage. Before entering a confined space where this chemical may be present, check to make sure that an explosive concentration does not exist. Trimethylbenzene must be stored to avoid contact with oxidizers (such as perchlorates, peroxides, permanganates, chlorates, and nitrates), and strong oxidizers (such as chlorine, bromine, and fluorine) since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat. Sources of ignition such as smoking and open flames are prohibited where this chemical is used, handled, or stored in a manner that could create a potential fire or explosion hazard. Metal containers involving the transfer of 5 gallons or more of this chemical should be grounded and bonded. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only nonsparking tools and equipment, especially when opening and closing containers of this chemical. /Trimethyl benzenes/STORAGE TANKS SHOULD BE MOUNDED TO CONFINE ESCAPING LIQUID & ESCAPE FROM PROCESS VESSELS SHOULD BE CONTROLLED IN SIMILAR MANNER BY SILLS @ DOORWAYS, DESIGN OF FLOORS, ETC. /TRIMETHYLBENZENES/ |
| Reinigungsverfahren | Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or similar material and deposit in sealed containers. Keep this chemical out of a confined space ... because of the possibility of an explosion ... It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable. /Trimethyl benzenes/ |
| Freisetung ohne Brand | Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: |
| Entsorgungsverfahren | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal, aquatic, and plant lifeand conformance with environmental and public health regulations.Incineration /SRP: with appropriate emission controls/. /Trimethyl benzenes/ |
| Verschüttetes entsorgen | Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. |
| Preventive Measures | SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.The worker should immediately wash the skin when it becomes contaminated.Work clothing that becomes wet or significantly contaminated should be removed and replaced.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Körperbelastung | 6 of 46 human adipose tissue samples contained unreported concentrations of 1,2,4-trimethylbenzene(1). |
| Wechselwirkungen | ... The toxicokinetics of 124TMB was studied in nine male, healthy volunteers exposed to solvent vapors in an exposure chamber for 2 hr during a work load of 50 W. The subjects were exposed to 2 ppm (11 mg/cu m) of 124TMB during exposure to 300 mg/cu m of white spirit. The 124TMB isomer was analysed in blood, urine and exhaled air by gas chromatography. The DMHA metabolites of all three TMB isomers were analysed in urine by high-performance liquid chromatography. The results were compared with previously published exposures to 2 and 25 ppm (120 mg/cu m) of 124TMB vapor alone. ... Blood levels of 124TMB and excretion rates of 3,4-DMHA in urine were markedly elevated both during and after exposure to white spirit compared to the same exposure level of 124TMB alone. ... It appears that components in white spirit interfere with the metabolic elimination of 124TMB. This should be considered in biological exposure monitoring as well as in risk assessment. |
| Zielorgane | DevelopmentalEyes, skin, respiratory system, central nervous system, blood |
| Ökotoxizitätswerte | EC50Species: Daphnia magna (Water flea, age 4-6 days, 1.5 mm)Conditions: freshwater, static, 23 °C, pH 6-7, dissolved oxygen 5-9 mg/LConcentration: 30 mmol/cu m for 48 hr (95% confidence interval: 13-69 mmol/cu m)Effect: intoxication, immobilizationLC50Species: Artemia salina (Brine shrimp, nauplii)Conditions: saltwater, static, 20 °CConcentration: 100 mmol/cu m for 24 hr /> or =97% purity/Species: Elasmopus pectinicrus (Scud, adult)Conditions: saltwater, renewal, 23 °C, salinity 30 pptConcentration: 5230 ug/L for 24 hr (95% confidence interval: 4890-5620 ug/L)Conditions: saltwater, renewal, 23 °C, salinity 30 parts per thousandConcentration: 4910 ug/L for 48 hr (95% confidence interval: 4500-5340 ug/L)For more Ecotoxicity Values (Complete) data for 1,2,4-TRIMETHYLBENZENE (9 total), please visit the HSDB record page. |
| Umweltverhalten | TERRESTRIAL FATE: Based on a recommended classification scheme(1), a Koc value of 537 measured in soil(2), indicates that 1,2,4-trimethylbenzene is expected to have low mobility in soil(SRC). Volatilization of 1,2,4-trimethylbenzene is expected to be important from moist soil surfaces(SRC) given a measured Henry's Law constant of 6.16X10-3 atm-cu m/mole(3) and from dry soil surfaces(SRC) based on a measured vapor pressure of 2.1 mm Hg at 25 °C(4). Complete removal of 1,2,4-trimethylbenzene from sterile sandy loam soil samples contaminated with jet fuel was reported within 5 days, probably due to evaporation(5). Non-volatilized 1,2,4-trimethylbenzene may be subject to biodegradation(SRC). 1,2,4-Trimethylbenzene was degraded within 7 days during a study of the aerobic microbial degradation of components of gas oil in aqueous solutionthis was demonstrated while contaminated water percolated through an unsaturated soil column(6).AQUATIC FATE: Based on a recommended classification scheme(1), a Koc value of 537 measured in soil(2), indicates that 1,2,4-trimethylbenzene is expected to adsorb to suspended solids and sediment in water(SRC). 1,2,4-Trimethylbenzene is expected to volatilize from water surfaces(3) based on a measured Henry's Law constant of 6.16X10-3 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are approximately 3 hours and 4 days, respectively(SRC). According to a classification scheme(5), BCF values of 31 to 275(6), measured in fish, suggest that bioconcentration in aquatic organisms is moderate to high(SRC). Biodegradation under aerobic conditions may be an important fate process for this compound in water although high concentrations of 1,2,4-trimethylbenzene may be toxic to the indigenous microbial population(6,7).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,2,4-trimethylbenzene, which has a measured vapor pressure of 2.10 mm Hg at 25 °C(2), will exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,2,4-trimethylbenzene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC)the half-life for this reaction in air is estimated to be about 12 hours(SRC), calculated from its rate constant of 3.25X10-11 cu cm/molecule-sec at 25 °C(3). 1,2,4-Trimethylbenzene also reacts with nitrate radicals in the atmosphere(4)the half-life for this reaction in air is estimated as 6-30 days(SRC), calculated from rate constants in the range of 5.4X10-16 to 2.70X10-15 cu cm/molecule-sec at 25 °C(4). 1,2,4-Trimethylbenzene does not contain chromophores that absorb at wavelengths >290 nm(5) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC). |
| Lebensmitteluntersuchungswerte | 1,2,4-Trimethylbenzene was reported as a component of pineapple guava (at 0.06 ug/g)(1), fried beef liver (88-125 ppb)(2), margarine (31.3 ppb)(2), butter (22.9 ppb)(2), cake doughnuts (94.3 ppb)(2), roasted filberts(3), in scrambled eggs from both fresh and supermarket eggs (trace levels)(4), chickpea seed(5) and fresh nectarines (trace levels)(6). 1,2,4-Trimethylbenzene is a volatile component of chicken, beef, and pork flavors(7). |
| Unerwünschte Wirkungen | Neurotoxin - Acute solvent syndrome |
| Expositionspfade | The substance can be absorbed into the body by inhalation.inhalation, ingestion, skin and/or eye contact |
| Average Daily Intake | The average daily dose of 1,2,4-trimethylbenzene from breathing air in The Netherlands was estimated as 86 ug/day based on average ambient air concentrations of 0.50-1.15 ppb(1). |
| Ökotoxizitätsauszüge | /AQUATIC SPECIES/ No stress was observed in Oncorhynchus mykiss (rainbow trout, fingerling) or Petromyzon marinus (sea lamprey, larvae) at 5 mg/L for 24 hours. |
| Signs and Symptoms | Confusion. Cough. Dizziness. Drowsiness. Headache. Sore throat. Vomiting.Redness. Dry skin.Redness. Pain.See Inhalation.irritation eyes, skin, nose, throat, respiratory systembronchitishypochromic anemiaheadache, drowsiness, lassitude (weakness, exhaustion), dizziness, nausea, incoordinationvomiting, confusionchemical pneumonitis (aspiration liquid) |
| Effluent Concentrations | 1,2,4-Trimethylbenzene was detected in automobile exhaustreported concn for mixture of sec- and tert-butylbenzene and 1,2,4-trimethylbenzene was 6.1 ppm(1). Automobile exhaust from an English car without a catalytic converter contained 1,2,4-trimethylbenzene at 3717 ppb(2). Highway tunnel exhaust air in Hamburg, Germany (Elbtunnel) contained 1,2,4-trimethylbenzene at concns from 47.6 to 59.8 ug/cu m(3). Highway tunnel exhaust air in Belgium (The Craeybeckx tunnel) in March/April 1991 contained 1,2,4-trimethylbenzene at an average concn of 15 ug/cu m(4). Automobile exhaust from a light-duty vehicle contained 1,2,4-trimethylbenzene at concns ranging from 1.13 to 3.33 wt% of total non-methane hydrocarbons(5). Gasoline engine exhaust from a light-duty vehicle both with and without a catalytic converter contained 1,2,4-trimethylbenzene at 1.8 and 1.9 wt% of total organic gas emissions, respectively(6). Unburned gasoline in the summertime contained 3.2 wt% 1,2,4-trimethylbenzene(6).1,2,4-Trimethylbenzene at 40 mg/10 minutes was introduced into water by a four-stroke outboard motor(1). The concn of 1,2,4-trimethylbenzene in the water of a canal to a harbor of Lake Constance, Germany, varied throughout the day with 7, 53, 507, 380, 518, 557, 557, and 614 ng/L reported for times 8:30, 9:37, 10:37, 11:40, 12:42, 15:20, 16:20, and 17:30 (1). A 7 and 10 horsepower outboard motor produced 7.9 and 24.2 ppm 1,2,4-trimethylbenzene, respectively, in 30 minutes in 160 liters water(2). 1,2,4-Trimethylbenzene was reported as one of the 99 most frequently detected compounds at Superfund sites(3). 1,2,4-Trimethylbenzene was detected in the gas emitted from a sludge landfill simulator at unreported concns(4). Emissions from a municipal waste incineration plant contained 1,2,4-trimethylbenzene at 1.17 ug/cu m(5). Emissions from coal-fired power stations in France contained 1,2,4-trimethylbenzene at 3.0 to 26.8 ug/Normalized cu m(6).1,2,4-Trimethylbenzene was detected in leachate samples from 6 of 6 hazardous waste landfills at concns from 10 to 3160 ug/L and in 5 of 5 leachate samples from domestic landfills at concns of 0.94 to 8.1 ug/L(1). 1,2,4-Trimethylbenzene was detected at 10 ug/L in the effluent from the Los Angeles County wastewater treatment plant(2). 1,2,4-Trimethylbenzene was detected in secondary effluent from the South Fort Polk Sewage Treatment Plant, Louisiana, at 0.034 and 0.084 ug/L(3). Influent to the Jones Island publicly-owned treatment plant contained 1,2,4-trimethylbenzene from 7 to 12 ppbeffluent contained less than 1 ppb(4). Effluent samples from an in situ coal gasification experiment in Hanna, WY contained 1,2,4-trimethylbenzene from not detected (detection limit = 0.1 ppb) to 267 ppb(5). Dissolved air flotation treatment effluent from a class B petroleum refinery contained 1,2,4-trimethylbenzene at 178 ng/g(6). Two of six mixed household waste samples contained 1,2,4-trimethylbenzene at unreported concns(7). Effluent samples collected from advanced waste treatment plants in Pomona, CA (in 1974/1975) and Orange County, CA (in 1976) contained 1,2,4-trimethylbenzene at unreported concns(8).Off-gas from two Ontario municipal wastewater treatment plants, Skyway in Burlington and Highland Creek in Metropolitan Toronto contained 1,2,4-trimethylbenzene at maximum concns of 499 and 471 ug/cu m, respectivelyemission rates of 64 and 198 g/d were estimated(1). Leachate from the North Bay, Ontario landfill contained 1,2,4-trimethylbenzene at concns of 0.6 to 220 ug/L(2). 1,2,4-Trimethylbenzene was detected in 5 of 5 hazardous waste landfill leachate samples (10-3160 ug/L) and 4 of 4 sanitary landfill leachate samples (0.94-8.1 ug/L)landfills are located in Germany(3). 1,2,4-Trimethylbenzene was detected in 13.8% of stormwater samples collected in the state of North Carolina at a mean concn of 0.13 ug/L and max concn of 0.76 ug/L(4). |
| Landesrichtlinien für Trinkwasser | (CA) CALIFORNIA 330 ug/l(FL) FLORIDA 35 ug/L(NH) NEW HAMPSHIRE 330 ug/L(WI) WISCONSIN 480 ug/l /Trimethylbenzenes/ |
| Berufliche Expositionsstufe (OEB) | A |
| Arbeitsplatzgrenzwert (OEL) | TWA: 25 ppm (125 mg/m3) |
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 3295 3/PG 3 |
| Zollcode | 29029090 |
| RTECS-Nr. | DC3325000 |
| R-Sätze (R) | 10-20-36/37/38-51/53-39/23/24/25-23/24/25-11-65 |
| Toxizität | LD50 i.p. in male, female mice (mg/kg): 5000, 4100 (Janik-Spiechowicz) |
| Gefahrensymbole | Xn,N,F,Xi,T |
| hazard_note | Irritant/Flammable |
| Sicherheitshinweise (S) | 26-61-45-36/37-16-7-62 |
| Gefahrenklasse | 3Acute Tox. 4 InhalationAquatic Chronic 2Asp. Tox. 1Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | III |
| Lagerklasse | 3 - Flammable liquids |
| Gefahrstoffdaten | 95-63-6(Hazardous Substances Data) |
| Selbstentzündungstemperatur | 959 °F |
Anwendungen & Verwendung
Beschreibung
1,2,4-Trimethylbenzene (mesitylene) is an aromatic hydrocarbon compound commonly present in commercial solvents encompassing their boiling range. Mesitylene are the most common isomer used in commercial applications. Aromatic hydrocarbons in hydrocarbon solvents are predominantly alkylated one ring structures as well as two aromatic ring structures which may also be alkylated.
Verwenden
1,2,4-Trimethylbenzene is the unlabelled version of 1,2,4-Trimethyl 13C6-benzene (T796173), a labelled aromatic standard.