HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Kresolrot
CR · BROMCRESOL PURPLE · O-CRESOLSULFONEPHTHALEIN · CRGF · NSC 7224 · cresolre · BETZ 0419 · Cresol Red
Identifikatoren & physikalische Daten
| CAS No. | 1733-12-6 |
|---|---|
| Summenformel | C21H18O5S |
| Durchschnittliche Molmasse | 382,4 g/mol |
| Monoisotopische Masse | 382,08749468 g/mol |
| SMILES | Cc1cc(C2(c3ccc(O)c(C)c3)OS(=O)(=O)c3ccccc32)ccc1O |
| InChIKey | OBRMNDMBJQTZHV-UHFFFAOYSA-N |
| PubChem CID | 73013 |
| ChEBI | CHEBI:86218 |
| EC No. | 217-064-2 |
| DTXSID | DTXSID8061929 |
| Lokaler Name | Kresolrot |
Chemische & physikalische Eigenschaften
| XLogP | 3,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 92,2 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 27 |
| Formalladung | 0 |
| Komplexität | 615 |
| Stoffklassen | Dyes -> Indicator Dyes |
| Physical Description | Reddish-brown solid[Merck Index] Reddish-brown or green odorless solid[CHEMINFO] Crystalline solid[MSDSonline] |
| Schmelzpunkt | 290 °C |
| Siedepunkt | 479.59°C (rough estimate) |
| Dichte | 0.998 g/cm3 |
| Brechungsindex | 1.5300 (estimate) |
| Lagerbedingungen | Store at +5°C to +30°C. |
| Löslichkeit | Solubility Sparingly soluble in watersoluble in ethanol |
| Aggregatzustand | Powder |
| pKa (Säurekonstante) | 1.0(at 25℃) |
| Farbe | Dark green or brown-red |
| pH | 7.2~8.8 |
| Merck | 14,2578 |
| BRN | 343399 |
| Hauptanwendungen | Display device, optical sensors, combustion gas detection system, inks, correction fluid, diapers, toothpaste, identifying fresh and stale rice, food storage, determine glucose in dialysis solution, monitor metabolic activity of microorganisms, detect bacterialinfection, psychoactive drugs, dental impression material |
| InChI | 1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3 |
| InChIKey | ASMGMVUGPNODGX-UHFFFAOYSA-N |
| SMILES | Cc1cc(ccc1O)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)c(C)c4 |
| EPA chemische Informationen | Cresol Red (1733-12-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 6.5% (3 of 46) of reports.WarningH315 (91.3%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2-methyl-, S,S-dioxidePhenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2-methyl-: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | May cause irritation[MSDSonline] |
| Hazard Classes and Categories | Skin Irrit. 2 (91.3%) |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN1170 - class 3 - PG 3 - Ethanol, solution |
| Zollcode | 29349990 |
| R-Sätze (R) | 36/37/38-20/21/22-11 |
| Toxizität | A potent lacrimator which is chemically stable and retains its irritancy in water and so can be used in liquid jets in personnel control. In addition to lacrimation, it causes eye pain, blepharospasm, eyelid swelling, irritation of the conjunctiva, a rise in intraocular pressure, and erythema of the skin. Because it can be used in water, its use is less affected by changes in climatic conditions. It is a more potent lacrimator than CS but it is less potent in lethality than CS. |
| Gefahrensymbole | Xi,Xn,F |
| Sicherheitshinweise (S) | 24/25-36-26-16 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.