Fenticlor

2,2'-THIOBIS(4-CHLOROPHENOL) · d25 · D 25 · cr305 · Novex · Oksid · CR 305 · Ph 549

Identifikatoren & physikalische Daten

CAS No.	97-24-5
Summenformel	C12H8Cl2O2S
Durchschnittliche Molmasse	287,2 g/mol
Monoisotopische Masse	285,9622061 g/mol
SMILES	Oc1ccc(Cl)cc1Sc1cc(Cl)ccc1O
InChIKey	ANUSOIHIIPAHJV-UHFFFAOYSA-N
PubChem CID	7329
ChEMBL	CHEMBL473535
ChEBI	CHEBI:556580
EC No.	202-568-7
DTXSID	DTXSID4026137
Lokaler Name	Fenticlor

Chemische & physikalische Eigenschaften

XLogP	4,5
Polarare Oberfläche (TPSA)	65,8
H-Brücken-Donoren	2
H-Brücken-Akzeptoren	3
Frei drehbare Bindungen	2
Schwere Atome	17
Formalladung	0
Komplexität	231
Löslichkeit	less than 1 mg/mL at 72 °F (NTP, 1992)
Schmelzpunkt	348.4 to 368.2 °F (NTP, 1992)175°C
Physical Description	2,2'-thiobis(4-chlorophenol) appears as white to cream-colored solid or pale yellow powder. White crystalline solid melting from 175.8-186.8 °C. Odorless and insoluble in water.White to cream-colored solid or pale yellow powder[CAMEO]
Siedepunkt	416.7±45.0 °C(Predicted)
Dichte	1.4186 (estimate)
Lagerbedingungen	Sealed in dry,Room Temperature
Aggregatzustand	powder to crystal
pKa (Säurekonstante)	7.91±0.48(Predicted)
Farbe	White to Orange to Green
Merck	14,4004
Stabilität	Stable. Incompatible with strong oxidizing agents.
Kosmetik-Inhaltsstoffe Funktionen	ANTIMICROBIAL
LogP (Verteilungskoeffizient)	4.400 (est)
CAS Datenbank	97-24-5(CAS DataBase Reference)
EPA chemische Informationen	Fenticlor (97-24-5)

Sicherheit & Vorschriften

GHS-Einstufung	DangerH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (97.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]H318 (97.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H413 (97.5%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P332+P317, P333+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Regulatorische Informationen	Phenol, 2,2'-thiobis[4-chloro-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Weitere Sicherheitsinformationen	IMAP assessments - Phenol, 2,2'-thiobis[4-chloro-: Human health tier I assessmentIMAP assessments - Phenol, 2,2'-thiobis[4-chloro-: Environment tier I assessment
Brandgefahren	Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992)
Gesundheitsgefahren	SYMPTOMS: This material may cause skin irritation.ACUTE/CHRONIC HAZARDS: This material may cause irritation of the skin on contact. Hazardous products are emitted when this chemical is heated to decomposition. (NTP, 1992)
Gefahrenübersicht	May be irritating to the skin[CAMEO] A photosensitizer reported in Canada, Britain, and Australia[Marks, p. 231-2]
Reaktive Gruppe	Sulfides, OrganicPhenols and CresolsAryl Halides
Reactivity Profile	2,2'-THIOBIS(4-CHLOROPHENOL) is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials may generate heat and toxic or flammable gases.
Air and Water Reactions	Insoluble in water.
Hazard Classes and Categories	Skin Irrit. 2 (100%)Skin Sens. 1 (97.5%)Eye Dam. 1 (97.5%)STOT SE 3 (97.5%)Aquatic Chronic 4 (97.5%)
Brandbekämpfung	Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Erste Hilfe	EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.INHALATION: IMMEDIATELY leave the contaminated areatake deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be usedif not available, use a level of protection greater than or equal to that advised under Protective Clothing.INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Freisetung ohne Brand	SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
Personal Protective Equipment (PPE)	RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Unerwünschte Wirkungen	Dermatotoxin - PACD (photoallergic contact dermatitis).
Zollcode	2930.90.2900
RTECS-Nr.	SN0350000
R-Sätze (R)	36/37/38
Toxizität	LDLo intraperitoneal in mouse: 250mg/kg
Sicherheitshinweise (S)	26-36/37/39
Gefahrenklasse	IRRITANT

Anwendungen & Verwendung

Verwenden

Fungicide; especially used against Monosporium apiospermum: Reifferscheid, Seeliger, Dtsch. Med. Wochenschr. 80, 1841, 1850 (1955).

Herstellung & Synthese

synthetische

Fenticlor is produced (1) by the reaction of 4-chlorophenol with sulfur dichloride in the presence of AlCl3 or (2) by chlorination of 2,2'-thiobisphenol with chlorine in glacial acetic acid or with SO2Cl2 in dichlorobenzene. It shows a tendency to discoloration. Fenticlor has a broad range of antimicrobial action; it is, e.g., effective against bacteria, fungi, yeasts, and algae. Fenticlor is therefore used as a preservative for aqueous functional fluids and to control algae and slime in process water circulation systems.