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(1-Methylethyl)benzol
ISOPROPYLBENZENE · 2-PHENYLPROPANE · CUMOL · i-propylbenzene · Cumeen · Isopropylbenzen · Isopropilbenzene · (1-METHYLETHYL)BENZENE
Identifikatoren & physikalische Daten
| CAS No. | 101316-43-2 |
|---|---|
| Summenformel | C9H12 |
| Durchschnittliche Molmasse | 120,19 g/mol |
| Monoisotopische Masse | 120,09390038 g/mol |
| SMILES | CC(C)c1ccccc1 |
| InChIKey | RWGFKTVRMDUZSP-UHFFFAOYSA-N |
| PubChem CID | 7406 |
| ChEMBL | CHEMBL1398949 |
| ChEBI | CHEBI:34656 |
| EC No. | 202-704-5 |
| DTXSID | DTXSID1021827 |
| Lokaler Name | (1-Methylethyl)benzol |
Chemische & physikalische Eigenschaften
| XLogP | 3,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 68,1 |
| Stoffklassen | Hazardous Air Pollutants (HAPs)Flammable agents - 3rd degreeVolatile Organic Compound (VOC) and(or) Waste-water effluent contaminant |
| Solvents | Solvents -> Aromatic Solvents |
| Kosmetika | Cosmetics ingredient -> Other (Specify) |
| SpringerMaterials Properties | 13C nuclear magnetic resonance spectrum |
| Pestizide | Pesticide -> EPA IRIS |
| LogP (Verteilungskoeffizient) | log Kow = 3.66 |
| Geruch | Gasoline-like odor... Sharp, penetrating, aromatic odor |
| Dichte | 0.866 at 59 °F (USCG, 1999) - Less dense than waterwill floatSpecific gravity: 0.862 at 20 °C/4 °C% in saturated air at 38.3 °C and 760 mm Hg: 1.32density of saturated vapor-air mixture at 38 °C and 760 mm Hg (Air = 1): 1.03Relative density (water = 1): 0.900.864 @25 °C0.864 g/mL at 25 °C(lit.) |
| Viscosity | 0.737 mPa.sec at 25 °C0.85 mm²/s at 25 °C |
| Color/Form | Colorless liquid |
| Dispersion | Specific dispersion: 166.2 |
| Löslichkeit | Insoluble (NIOSH, 2024)In water, 61.3 mg/L at 25 °CIn water, 50 mg/L at 20 °CMiscible with ethanol, ethyl ether, acetone, benzene, petroleum ether, carbon tetrachlorideSoluble in many organic solvents0.0613 mg/mL at 25 °C0.05g/lSoluble in alcohol, ether, acetone, benzene, carbon tetrachloride. Insoluble in water. |
| Schmelzpunkt | −96 °C(lit.) |
| Siedepunkt | 152-154 °C(lit.) |
| Dampfdichte | 4.1 (vs air) |
| Dampfdruck | 8 mm Hg ( 20 °C) |
| Brechungsindex | n20/D 1.491(lit.) |
| Flammpunkt | 115 °F |
| Lagerbedingungen | 2-8°C |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | >14 (Schwarzenbach et al., 1993) |
| Farbe | Clear colorless |
| Geruch | Strong, slightly irritantfragrantaromatic. |
| Geruchsschwelle | 0.0084ppm |
| Explosionsgrenze | 0.8-6.0%(V) |
| Spezifische Wärmekapazität | Cp(liquid): 1.75 J/(g·K), at 25℃ |
| Merck | 14,2617 |
| BRN | 1236613 |
| Henry-Konstante | 13.0, 15.3, and 23.9 at 28.0, 35.0, and 46.1 °C, respectively (headspace method, Hansen et al., 1993) |
| Dielektrizitätskonstante | 2.4(20℃) |
| Stabilität | Stable, but may form peroxides in storage if in contact with the air. Test for the presence of peroxides before heating or distilling. Combustible. Incompatible with strong oxidizing agents. |
| InChI | 1S/C9H12/c1-8(2)9-6-4-3-5-7-9/h3-8H,1-2H3 |
| InChIKey | RWGFKTVRMDUZSP-UHFFFAOYSA-N |
| SMILES | CC(C)c1ccccc1 |
| LogP (Verteilungskoeffizient) | 3.55 at 20℃ |
| Oberflächenspannung | 28.21mN/m at 20°C |
| CAS Datenbank | 98-82-8(CAS DataBase Reference) |
| NIST chemische Informationen | Benzene, (1-methylethyl)-(98-82-8) |
| EPA chemische Informationen | Cumene (98-82-8) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH226: Flammable liquid and vapor [Warning Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P271, P273, P280, P301+P316, P303+P361+P353, P304+P340, P318, P319, P331, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for < 0.1% (1 of 3187) of reports.H226 (> 99.9%): Flammable liquid and vapor [Warning Flammable liquids] |
|---|---|
| Regulatorische Informationen | Chemical: Benzene, (1-methylethyl)-Hazard Traits - CarcinogenicityDermatotoxicityEndocrine ToxicityHepatotoxicity and Digestive System ToxicityNephrotoxicity and Other Toxicity to the Urinary SystemNeurotoxicityOcular ToxicityBenzene, (1-methylethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzene, (1-methylethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 03-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15387Benzene, (1-methylethyl)-: HSNO Approval: HSR001184 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | IMAP assessments - Benzene, (1-methylethyl)-: Environment tier I assessment |
| DOT-Kennzeichnung | Flammable Liquid |
| Brandgefahren | Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.Flammable. Above 31 °C explosive vapour/air mixtures may be formed. |
| Brandpotenzial | Flammable liquid. |
| Gesundheitsgefahren | Narcotic action with long-lasting effectsdepressant to central nervous system. (USCG, 1999)· May cause toxic effects if inhaled or absorbed through skin. |
| Gefahrenübersicht | Cumene is used in a variety of petroleum products. Acute (short-term) inhalation exposure to cumene may cause headaches, dizziness, drowsiness, slight incoordination, and unconsciousness in humans. Cumene has a potent central nervous system (CNS) depressant action characterized by a slow induction period and long duration of narcotic effects in animals. Cumene is a skin and eye irritant. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of cumene in humans. Animal studies have reported increased liver, kidney, and adrenal weights from inhalation exposure to cumene. EPA has classified cumene as a Group D, not classifiable as to human carcinogenicity.Liver toxicity occurs in mice inhaling 500-1000 ppm daily for 17 days. TLV Basis is upper respiratory tract adenoma and neurological effects. [ACGIH] Inhalation of high concentrations may cause CNS effectsA skin, eye, and respiratory tract irritant[ICSC] Fatty liver changes are noted in animals exposed to lethal doses[HSDB] |
| DOT-Nummer und Handbuch | 1918 130 |
| Reaktive Gruppe | Hydrocarbons, Aromatic |
| EG-Einstufung | Symbol: Xn, NR: 10-37-51/53-65S: (2)-24-37-61-62Note: C |
| UN-Einstufung | UN Hazard Class: 3UN Pack Group: III |
| Special Reports | ITC/USEPAInformation Review #464 (Draft) Cumene (1984)National Research CouncilThe Alkyl Benzenes (1981)U.S. Environmental Protection Agency's Integrated Risk Information System (IRIS) for Cumene (98-82-8) Toxicological Review in Adobe PDF.[Available from, as of August, 1997: http://www.epa.gov/iris/] |
| Brandbekämpfung | Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:Use powder, AFFF, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. |
| Erste-Hilfe-Maßnahmen | Fresh air, rest. Refer for medical attention.Remove contaminated clothes. Rinse and then wash skin with water and soap.Rinse with plenty of water (remove contact lenses if easily possible).Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. |
| Freisetungsmaßnahmen | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| Erste Hilfe | Excerpt from NIOSH Pocket Guide for Cumene:General First Aid:(General first aid procedures) |
| Sichere Lagerung | Fireproof. Separated from strong oxidants and acids. Cool. Keep in the dark. Store only if stabilized. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. |
| Expositionsschutz und Persönliche Schutzausrüstung | · Wear positive pressure self-contained breathing apparatus (SCBA).10.0 [ppm] |
| Brandbekämpfungsverfahren | To fight fire, use foam, carbon dioxide, dry chemical.Use water spray, dry chemical, foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool. |
| Lagerbedingungen | ... Precautions ... such as mounds around storage tanks, sills at doorways or especially designed floors /are needed/ to limit spread of escaping liquid. Open flames & other sources of ignition should be excluded where cumene is stored.Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage warehouse, room, or cabinet. Separate from oxidizing materials, nitric acid, sulfuric acid.Storage temperature: Ambient. |
| Reinigungsverfahren | Personal protection: filter respirator for organic gases and vapors adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.Remove all ignition sourcesventilate /the/ area of spill or leak. For small quantities absorb on paper towels /and/ evaporate in a safe place (such as a fume hood). Allow sufficient time for evaporating vapors to completely clear the hood ductwork. |
| Freisetung ohne Brand | Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]: |
| Entsorgungsverfahren | Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U055, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.Cumene is a waste chemical stream constituent which may be subjected to ultimate disposal by controlled incineration.A good candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds. A good candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A good candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.... Large quantities can be collected and atomized in a suitable combustion chamber. Combustion may be improved by mixing with a flammable liquid. Cumene liquid should not be allowed to enter a confined space, such as a sewer, because of the possibility of an explosion.For more Disposal Methods (Complete) data for Isopropylbenzene (6 total), please visit the HSDB record page. |
| Verschüttetes entsorgen | Personal protection: chemical protection suit and filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. |
| Körperbelastung | Isopropylbenzene has been detected at 0.13 ug/hour(1) and detected but not quantified(2) in human expired air from non-smoking individuals.Isopropylbenzene concentration in air samples from non-smoking married females residing in New Jersey and Pennsylvania, in both smoking and nonsmoking homes and nonsmoking workplaces(1).[Table#628] |
| Treatment | Treatment is mainly symptomatic and supportive. Gastric lavage, emesis, and the administration of activated charcoal should be avoided, as vomiting increases the risk of aspiration. (A600) |
| Zielorgane | EndocrineEyes, skin, respiratory system, central nervous system |
| Gesundheitliche Auswirkungen | Petroleum distillates are aspiration hazards and may cause pulmonary damage, central nervous system depression, and cardiac effects such as cardiac arrhythmias. They may also affect the blood, immune system, liver, and kidney. (A600, L1297) |
| Ökotoxizitätswerte | LC50Species: Daphnia magna (Water flea)Concentration: 0.6 ppm for 48 hr /Conditions of bioassay not specified/LD50Species: Agelaius phoeniceus (red-winged blackbird) oral 98 mg/kgSpecies: Pimephales promelas (fathead minnow)Conditions: flow-through bioassay with measured concentrations, 25.4 °C, dissolved oxygen 6.6 mg/L, hardness 44.3 mg/L calcium carbonate, alkalinity 42.1 mg/L calcium carbonate, and pH 7.58Concentration: 6.32 mg/L for 96 hr (confidence limit 6.04-6.61 mg/L)EC50Condtions: flow-through bioassay with measured concentrations, 25.4 °C, dissolved oxygen 6.6 mg/L, hardness 44.3 mg/L calcium carbonate, alkalinity 42.1 mg/L calcium carbonate, and pH 7.58Effect: loss of equilibrium. Affected fish lost schooling behavior and swam in a corkscrew/spiral pattern. They were hyperactive and darkly colored, had increased respiration, and lost equilibrium prior to death.For more Ecotoxicity Values (Complete) data for Isopropylbenzene (14 total), please visit the HSDB record page. |
| Umweltverhalten | TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 700(SRC), determined from a structure estimation method(2), indicates that isopropylbenzene is expected to have low mobility in soil(SRC). Volatilization of isopropylbenzene from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 1.15X10-2 atm-cu m/mole(3). Isopropylbenzene is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 4.5 mm Hg at 25 °C(4). A biodegradation half-life of 2 days (rate constant = 0.322/day) was calculated for isopropylbenzene added to soil microcosms from a weathered petroleum spill site(5), indicating that biodegradation may be an important environmental fate process in soil(SRC).AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 700(SRC), determined from a structure estimation method(2), indicates that isopropylbenzene is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 1.15X10-2 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 3 hrs and 4 days, respectively(SRC). According to a classification scheme(5), a BCF of 35.5(6), suggests the potential for bioconcentration in aquatic organisms is moderate(SRC). Isopropylbenzene, incubated in a sediment/freshwater ecocore, exhibited a mineralization rate of 0.02/day, corresponding to a half-life of 34.6 days(7), indicating that biodegradation may be an important environmental fate process in water(SRC).AQUATIC FATE: In an experiment to study the disappearance of organic compounds found in crude oil during an oil spill, isopropylbenzene was found to disappear (combination of evaporation and dissolution) within 90 minutes of being spilled into seawater(1). In a similar experiment, water samples taken from an oil spill in the Canadian Arctic waters in the Ragged Channel revealed that after 6 hours, isopropylbenzene could not be detected in the aromatic fraction(2). Isopropylbenzene has a reported volatilization half-life in water ranging from 3.2 to 5.8 hrs(3).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), isopropylbenzene, which has a vapor pressure of 4.5 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase isopropylbenzene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC)the half-life for this reaction in air is estimated to be 1.5 days(SRC), calculated from its rate constant of 6.5X10-12 cu cm/molecule-sec at 25 °C(3). Isopropylbenzene exhibits a UV absorption of 258 nm in cyclohexane(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). |
| Lebensmitteluntersuchungswerte | Trace quantities of isopropylbenzene have been detected in the total volatiles of Sapodilla fruit (Achras sapota)(1) and Australian honey(2). Isopropylbenzene was detected not quantified in fried chicken(3), Concord grapes (Vitis labrusca) and Zinfandel wine(4), cooked rice(5), oat groats (Avena sativa)(6), Idaho Russet Burbank baked potatoes(7), Beaufort cheese from the French Alps(8), and fried bacon(9). Isopropylbenzene has been identified as one of several volatile hydrocarbons found in chicken and pork(10).Seventy foods were analyzed for volatiles from 1996-2000 as part of the US FDA Total Diet Program(1). |
| Unerwünschte Wirkungen | Neurotoxin - Acute solvent syndrome |
| Expositionspfade | The substance can be absorbed into the body by inhalation, through the skin and by ingestion.inhalation, skin absorption, ingestion, skin and/or eye contactOral (L400)inhalation (L400)dermal (L400) |
| Milk Concentrations | EXPERIMENTAL: Analysis was conducted of 35 cow's milk samples purchased from 8 grocery stores in Las Vegas, NV January 2002 through February 2002method detection limit = 0.03 ng/mL(1). |
| Toxizitätsübersicht | IDENTIFICATION: Cumene is a water insoluble petrochemical used in the manufacture of several chemicals, including phenol and acetone. HUMAN EXPOSURE: In humans, cumene is metabolized primarily to the secondary alcohol. 2-phenyl-2-propranol. This alcohol and its conjugates are readily excreted by humans. No data are available with which to quantify human exposure. It is not possible to assess its potential for carcinogenicity in humans, because long term carcinogenicity studies with the chemical have not been performed. ANIMAL/PLANT STUDIES: Cumene is metabolized primarily to the secondary alcohol, 2-phenyl-2-propanol in animals. This alcohol and its conjugates are readily excreted by rodents. Increases in organ weights, primarily the kidney weughts are the most prominent effects observed in rodents readily exposed to cumene by either the oral or inhalation route. No adverse effects were observed in rat or rabbit fetuses whose mothers had been exposed to cumene during fetal development. Although no multigenerational reproductive studies have been performed using cumene, the rapid metabolism and excretion, coupled with the lack of effects on sperm morphology in a subchronic study, suggest that it has a low potential for reproductive toxicity. Most genotoxicity test data with cumene are negative. Inadequate data, especially measured exposure information, exist to allow a quantitative evaluation of the risk to populations of aquatic ot terrestrial organisms from exposure to cumene. Values indicate a slight potential for bioconcentration in fish. There are no data on the bioaccumulation in fish.Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) |
| Ökotoxizitätsauszüge | /AQUATIC SPECIES/ Mytilus edulis (mussel larvae) /blue mussel/: no significant alteration of growth rate at concentrations of 1 to 50 ppm./AQUATIC SPECIES/ Cumene at 0.5 mL/L within 24 hr caused 100% mortality of both crabs Asellus aquaticus L and Gammarus fossarum Koch (Isopoda, Amphipoda)./AQUATIC SPECIES/ One-day exposure to cumene at 0.05 and 0.1% caused 100% death of Radix peregra /wandering pond snail/ and Lymnea stagnalis /great pond snail/, respectively. ... Water temperature, pH, and total hardness had no effect on the toxic effect of the compound. The only important factor was oxygen, so the water was aerated during the experiments. |
| RCRA-Anforderungen | U055As stipulated in 40 CFR 261.33, when cumene, as a commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate, becomes a waste, it must be managed according to Federal and/or State hazardous waste regulations. Also defined as a hazardous waste is any residue, contaminated soil, water, or other debris resulting from the cleanup of a spill, into water or on dry land, of this waste. Generators of small quantities of this waste may qualify for partial exclusion from hazardous waste regulations (40 CFR 261.5). |
| TSCA-Anforderungen | Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. Cumene is included on this list. Effective date: 12/28/84Sunset date: 12/28/94. |
| Luftstandards | This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Cumene is produced, as an intermediate or a final product, by process units covered under this subpart.Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Cumene is included on this list. |
| CERCLA-Meldepflichtmengen | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). |
| Landesrichtlinien für Trinkwasser | (CA) CALIFORNIA 770 ug/l(FL) FLORIDA 700 ug/l(MN) MINNESOTA 300 ug/l(NH) NEW HAMPSHIRE 800 ug/l |
| F | 10 |
| Berufliche Expositionsstufe (OEB) | A |
| Arbeitsplatzgrenzwert (OEL) | TWA: 50 ppm (245 mg/m3) [skin] |
| Wassergefährdungsklasse (WGK) | 1 |
| Sofort lebensgefährliche Konzentration | 900 ppm [10% LEL] |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1918 |
| Zollcode | 29027000 |
| RTECS-Nr. | GR8575000 |
| R-Sätze (R) | 10-37-51/53-65-39/23/24/25-23/24/25-11 |
| Toxizität | LD50 orally in rats: 2.91 g/kg (Smyth) |
| Gefahrensymbole | Xn,N,T,F |
| Sicherheitshinweise (S) | 24-37-61-62-45-36/37-16 |
| Gefahrenklasse | 3Aquatic Chronic 2Asp. Tox. 1Carc. 1BFlam. Liq. 3STOT SE 3 |
| Verpackungsgruppe | III |
| Lagerklasse | 3 - Flammable liquids |
| Gefahrstoffdaten | 98-82-8(Hazardous Substances Data) |
| Selbstentzündungstemperatur | 797 °F |
Anwendungen & Verwendung
Beschreibung
Cumene is a common name for isopropylbenzene, an organic compound. Cumene is a volatile colorless liquid at room temperature with a characteristic sharp, penetrating, aromatic odor. It is insoluble in water but is soluble in alcohol and many other organic solvents. Cumene is structurally a member of the alkyl aromatic family of hydrocarbons, which also includes toluene (methylbenzene) and ethylbenzene.Cumene can be found in crude oil, refined fuels, and is a part of processed highoctane gasoline. Cumene is manufactured by reacting benzene with propylene at elevated temperature and pressure in the presence of a catalyst. It is considered an environmental pollutant because it is a natural component of petroleum and is present in tobacco smoke. Cumene vapor can be absorbed by the respiratory tract. Sufficiently high levels of exposure to cumene causes central nervous system (CNS) depression leading to death, internal bleeding of numerous organs, as well as irritation of the eyes and respiratory system, skin, and mucous membranes. Cumene is a high production volume chemical.
Verwenden
Around 98% of cumene is used in the production of phenol and its coproduct, acetone, using cumene hydroperoxide as chemical intermediate. However, the demand for cumene is largely dependent on the performance of phenol’s derivatives, which have resulted in healthy growth rates in demand for cumene. It is also used as a starting material in the production of acetophenone, α-methylstyrene, diisopropylbenzene, and dicumylperoxide. Cumene is used as a thinner for paints, lacquers, and enamels. It is also used in the manufacture of acetophenone, methylstyrene, and other chemicals commonly found in home cleaning products. Minor uses of cumene include as a constituent of some petroleum-based solvents, such as naphtha; in gasoline blending diesel fuel and highoctane aviation fuel; and as a raw material for peroxides and oxidation catalysts such as polymerization catalysts for acrylic and polyester-type resins. It is also a good solvent for fats and resins and has been suggested as a replacement for benzene in many of its industrial applications.