HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-Chlorpropoxy)-4-fluorbenzol
TIMTEC-BB SBB003674 · 1-(3-Chloropropoxy)- · 4-Fluorochloropropylanisole · Fluorophenoxy)propylchloride · 1-(3-Chloropropoxy)-4-fluoro · 4-Fluorophenoxypropyl chloride · 1-Chloro-3-(4-fluorophenoxy)pr · 3-(4-FLUOROPHENOXY)PROPYL CHLORIDE
Identifikatoren & physikalische Daten
| CAS No. | 1716-42-3 |
|---|---|
| Summenformel | C9H10ClFO |
| Durchschnittliche Molmasse | 188,62 g/mol |
| Monoisotopische Masse | 188,04042084 g/mol |
| SMILES | Fc1ccc(OCCCCl)cc1 |
| InChIKey | DFFWYMMOMUTKOI-UHFFFAOYSA-N |
| PubChem CID | 74391 |
| EC No. | 217-000-3 |
| DTXSID | DTXSID50169136 |
| Lokaler Name | 1-(3-Chlorpropoxy)-4-fluorbenzol |
Chemische & physikalische Eigenschaften
| XLogP | 2,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 9,2 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 4 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 113 |
| Siedepunkt | 118-120 °C (10 mmHg) |
| Dichte | 1.2 |
| Brechungsindex | 1.504-1.508 |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| CAS Datenbank | 1716-42-3(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 7 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| UN-Transportnummer | 3265 |
| Zollcode | 29093090 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| hazard_note | Irritant |
| Sicherheitshinweise (S) | 24/25-36-26 |
Anwendungen & Verwendung
Verwenden
1-(3-Chloropropoxy)-4-fluorobenzene was used as a reagent in the preparation of a library of hydantoin compds which has used to study Aurora kinase A inhibitory activity. It was also used as an alkylation agent in the preparation of tetracyclic quinoxaline butyrophenones as 5-HT2A and postsynaptic D2 antagonists and inhibitors of serotonin transporter for treatment of neuropsychiatric and neurological disorders.