1,4-Diisopropylbenzol

0.8568 AT 20 °C/4 °C

0.8568 @ 20°C

INSOL IN WATER

Sol in all proportions of alcohol, ether, acetone, benzene.

210.3 °C

210.3 °C @760 [mm Hg]

-17.1 °C

-17 °C

0.24 [mmHg]

1 MM HG AT 40.0 °C

Liquid; Gas Vapor

White solid; [HSDB] Colorless liquid; [MSDSonline]

This chemical does not meet GHS hazard criteria for 6.7% (5 of 75) of reports.

Warning

H315 (74.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P271, P273, P280, P302+P352, P304+P340, P318, P319, P321, P332+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 75 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

Benzene, 1,4-bis(1-methylethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzene, 1,4-bis(1-methylethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 10-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15776

Benzene, 1,4-bis(1-methylethyl)-: Does not have an individual approval but may be used under an appropriate group standard

Skin Irrit. 2 (74.7%)

Flammable liquids - Category 4

2.7 [mg/m3]

30 [mg/m3]

180 [mg/m3]

OF 10 RATS DOSED WITH 0.5 ML/KG ... ONE DEATH ... OCCURRED.

Diisopropylbenzene occurs in three isomeric forms, namely as the ortho, the meta, and the para derivatives ... . Orally, they are of very low toxicity. Of 10 rats dosed with 5.0 ml/kg, no deaths for the meta, and one death for the ortho and the para isomers occurred. Russian reports of 1970 indicate that rats and rabbits exposed to 0.2 to 1.0 mg/liter (30 to 150 ppm) for 90 minutes daily for 5 weeks developed vascular hyperemia, hemorrhaging in most major organs, and fatty and protein dystrophy in the liver, kidney, and heart, and hyperplasia of the bone marrow. meta-Diisopropylbenzene caused decreased fertility in the rat and mouse at 1 to 3 mg/liter for 30 days.

Diisopropylbenzene rated 1 on rabbit eyes /on a scale of 1 to 10 with 10 being the most severe/. /Diisopropylbenzene/

Used as a solvent and chemical intermediate; [HSDB]

SOLVENT; INTERMEDIATE

CHEM INT, EG, FOR HYDROQUINONE & ACETONE

2023: 55,000,000 - <70,000,000 lb

(1979) AT LEAST 2.27X10+6 G /UNSPECIFIED ISOMER/

(1981) AT LEAST 2.27X10+6 G /UNSPECIFIED ISOMER/

Petroleum Refineries

Benzene, 1,4-bis(1-methylethyl)-: ACTIVE