Terephtaloyldichlorid

Terephthaloyl chloride

HCID 7488CAS 100-20-9

Grundinformationen

Standard-SMILES
O=C(Cl)c1ccc(C(=O)Cl)cc1
InChIKey
LXEJRKJRKIFVNY-UHFFFAOYSA-N
Summenformel
C8H4Cl2O2
Durchschnittliche Molmasse
203,02 g/mol
Monoisotopische Masse
201,95883473

Überblick

cross-links albumin

Namen und Bezeichner

Bevorzugter Name
Terephthaloyl chloride
IUPAC
benzene-1,4-dicarbonyl chloride
Lokaler Name
Terephtaloyldichlorid
Englischer Name
Terephthaloyl chloride
Summenformel
C8H4Cl2O2
Molmasse
203.02

Namen und Synonyme

Terephthaloyl chloride100-20-9Terephthaloyl dichloride1,4-BENZENEDICARBONYL DICHLORIDEp-Phthaloyl chlorideTerephthalic acid dichlorideTerephthalic dichloridep-Phthaloyl dichlorideTerephthalyl dichloridep-Phenylenedicarbonyl dichloride1,4-Benzenedicarbonyl chlorideDTXSID7026653
Weitere Namen anzeigen
TCLTerephtaloyl chloridebis(forMaldehyde)TEREPHTHALYL CHLORIDE1,4-dichloroformylbenzenep-PhthaL
NSC-41885G247CO9608DTXCID506653RefChem:4159231,4-phthaloyl dichloride202-829-5Terephthalic acid chloridebenzene-1,4-dicarbonyl chloride

Datenbank-Bezeichner

CAS
100-20-9
PubChem CID
7488
DTXSID
DTXSID7026653
ChEMBL
CHEMBL1893301
UNII
G247CO9608
EC Number
202-829-5
Nikkaji
J4.979D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4
Polarare Oberfläche (TPSA)
34,1 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
2
Schwere Atome
12

Experimentelle und physikochemische Eigenschaften

Chemical ClassesToxic Gases & Vapors -> Acid Halides
SpringerMaterials PropertiesBoiling point
LogP0.88 (calculated)
Density1.32 g/cm³
Color/FormCOLORLESS NEEDLES
Solubility · 2 Einträge

SOLUBLE IN ETHER

Solubility in water: reaction

Physikochemische Eigenschaften

Schmelzpunkt
79 · 79-81 °C(lit.)
Siedepunkt
266 °C · 266 °C(lit.)
Dichte
1 · 1,34 g/cm3
Dampfdichte
7 · 7 (vs air)
Dampfdruck
0.02 mm · 0.02 mm Hg ( 25 °C)
Brechungsindex
1.5684 · 1.5684 (estimate)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 88.7% (2008 of 2263) of all reports.

Danger

H314 (11.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2263 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: 1,4-Benzenedicarbonyl dichloride

1,4-Benzenedicarbonyl dichloride is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Benzenedicarbonyl dichloride are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 29-04-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/13172

Terephthaloyl dichloride: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsCombustible. Gives off irritating or toxic fumes (or gases) in a fire. Finely dispersed particles form explosive mixtures in air.
Hazards Summary · 1 Eintrag

A reproductive effector; Causes asphyxiation by upper airway obstruction after lethal-dose inhalation studies of mice; [RTECS] Dust/air mixture may be explosive; Reacts with water producing hydrogen chloride; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause upper airway edema and pulmonary edema; [ICSC] A skin irritant; [HSDB] Reacts with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; A lachrymator; Inhalation may cause chemical pneumonitis; Effects in high-dose animal studies include lacrimation, changes in renal tubules and other changes to the brain; [MSDSonline]

Chemical DangersDecomposes on heating. This produces toxic and corrosive fumes. Reacts with strong oxidants. Reacts with water. This produces hydrogen chloride (see ICSC 0163). Attacks many metals in the presence of water.
Physical DangersDust explosion possible if in powder or granular form, mixed with air.
Hazard Classes and Categories · 2 Einträge

Skin Corr. 1A (11.2%)

Skin corrosion/irritation - Category 1

Sicherheit und Schutzausrüstung

Fire FightingUse dry sand, powder, carbon dioxide. NO hydrous agents.
First Aid Measures · 4 Einträge

Fresh air, rest. Half-upright position. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .

Safe StorageSeparated from strong oxidants. Dry. Well closed. Do NOT store or transport in containers made from metal.
Spillage Disposal · 1 Eintrag

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered plastic containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Eye PreventionWear safety goggles or eye protection in combination with breathing protection.
Fire PreventionNO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.

Toxikologische Informationen

Adverse EffectsDermatotoxin - Skin burns.
Exposure RoutesSerious by all routes of exposure.
Signs and Symptoms · 4 Einträge

Cough. Sore throat. Burning sensation. Laboured breathing. Shortness of breath. Symptoms may be delayed.

Redness. Pain. Skin burns.

Redness. Pain. Blurred vision. Severe deep burns.

Abdominal pain. Nausea. Vomiting. Diarrhoea. Shock or collapse.

Toxicity DataLC50 (rat) = 700 mg/m3/4h

Sicherheitsdaten

wgk
3
tsca
TSCA listed
ridadr
UN 2923 8/PG 3
hs_code
29173980
RTECS-Nr.
WZ1797000
risk_code
34-23-35

Chemie und Industrie

Verwendung und Herstellung

Uses · 4 Einträge

Used in dyes, synthetic fibers, resins, films, pharmaceuticals, rubber chemicals, and as a cross-linking agent for polyurethanes and polysulfides; [HSDB]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry]

DYE MANUFACTURE; SYNTHETIC FIBERS, RESINS, FILMS; ULTRAVIOLET ABSORPTION; PHARMACEUTICALS; RUBBER CHEMICALS

CROSS-LINKING AGENT FOR POLYURETHANES AND POLYSULFIDES

U.S. Production2023: 250,000 - <400,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesIntermediate
General Manufacturing Information · 2 Einträge

Plastics Material and Resin Manufacturing

1,4-Benzenedicarbonyl dichloride: ACTIVE

Anwendungen · 1 Eintrag

VerwendenTerephthaloyl chloride acts as a monomer with p-phenylenediamine used in the preparation of polymer viz. poly paraphenylene terephthalamide. It is an active component in performance polymers and aramid fibers, which gives flame resistance, chemical resistance, temperature stability, light weight, and very high strength. It is also used as an effective water scavenger, utilized to stabilize isocyanates and urethane prepolymers. Further, it is used in the preparation of liquid crystalline thermosets by thermal cyclotrimerization of dicyanate compounds of ring substituted bis(4-hydroxyphenyl) terepthalates. In addition to this, it is involved in the condensation reaction with difunctional alfa, μ-diaminopolystyrene to get chain-extended polystyrene containing amide bonds along the polymer backbone.

Darstellung · 1 Eintrag

synthetischeSynthesis of terephthaloyl chloride by thionyl chloride method: terephthalic acid is mixed with thionyl chloride, refluxed at 80℃ for 10-12h, then the thionyl chloride is evaporated, and the resulting crude product is distilled under reduced pressure to obtain the finished product.

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]

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