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4-Ethylmorpholin
HEM · 4-ETHYLMORPHOLINE · Ethylmorpholine · N-Ethylmorfolin · Texacat NEM · Toyocat -NEM · LUPRAGEN(R) N 104 · N-ETHYLMORPHOLINE
Identifikatoren & physikalische Daten
| CAS No. | 100-74-3 |
|---|---|
| Summenformel | C6H13NO |
| Durchschnittliche Molmasse | 115,17 g/mol |
| Monoisotopische Masse | 115,09971404 g/mol |
| SMILES | CCN1CCOCC1 |
| InChIKey | HVCNXQOWACZAFN-UHFFFAOYSA-N |
| PubChem CID | 7525 |
| ChEMBL | CHEMBL3561880 |
| EC No. | 202-885-0 |
| DTXSID | DTXSID5025312 |
| Lokaler Name | 4-Ethylmorpholin |
Chemische & physikalische Eigenschaften
| XLogP | 0 |
|---|---|
| Polarare Oberfläche (TPSA) | 12,5 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 59,5 |
| Stoffklassen | Nitrogen Compounds -> MorpholinesFlammable agents - 3rd degree |
| SpringerMaterials Properties | Viscosity |
| Geruch | AMMONIACAL ODORAmmonia-like odor. |
| Dichte | 0.916 at 68 °F (USCG, 1999) - Less dense than waterwill float0.8996 @ 20 °C/4 °CRelative density (water = 1): 0.990.900.91 g/mL at 20 °C (lit.) |
| Viscosity | 1.08 mPa S @ 20 °C |
| Color/Form | COLORLESS LIQUIDColorless liquid. |
| Löslichkeit | greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)SOL IN ALL PROPORTIONS IN WATER, ETHANOL & ETHERSOL IN ACETONESolubility in water: miscible |
| Flammpunkt | 82 °F (NTP, 1992)32 °C90 °F (32 °C) (OPEN CUP)(oc) 90 °F |
| Siedepunkt | 280 to 282 °F at 760 mmHg (NTP, 1992)138-139 °C @ 763 MM HG138 °C281 °F139 °C (lit.) |
| Schmelzpunkt | -81 °F (NTP, 1992)-62.78 °C-63 °C-63 °C (lit.) |
| Dampfdichte | 4 (NTP, 1992) - Heavier than airwill sink (Relative to Air)4.0 (AIR= 1)Relative vapor density (air = 1): 4.0 |
| Geruchsschwelle | Odor Threshold Low: 0.08 [ppm] |
| Dampfdruck | 8.1 hPa (20 °C) |
| Brechungsindex | n20/D 1.441(lit.) |
| Lagerbedingungen | Store below +30°C. |
| Aggregatzustand | Powder |
| pKa (Säurekonstante) | 7.67(at 25℃) |
| Farbe | Cream to beige to brown-grey |
| pH | 11.8 (100g/l, H2O, 20℃) |
| Explosionsgrenze | 1.9%(V) |
| BRN | 102969 |
| Henry-Konstante | 4.0×102 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stabilität | Stable. Flammable. Incompatible with strong oxidizing agents. Slightly air sensitive. |
| InChI | 1S/C6H13NO/c1-2-7-3-5-8-6-4-7/h2-6H2,1H3 |
| InChIKey | HVCNXQOWACZAFN-UHFFFAOYSA-N |
| SMILES | CCN1CCOCC1 || CCN1CCOCC1 |
| LogP (Verteilungskoeffizient) | 0.08 at 24.6℃ |
| CAS Datenbank | 100-74-3(CAS DataBase Reference) |
| NIST chemische Informationen | Morpholine, 4-ethyl-(100-74-3) |
| EPA chemische Informationen | N-Ethylmorpholine (100-74-3) |
| Absorption | cut-off at 300nm |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 1% (5 of 484) of reports.DangerH226 (99%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 484 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Morpholine, 4-ethyl-Morpholine, 4-ethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Morpholine, 4-ethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 25-01-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/177274-Ethylmorpholine: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| DOT-Kennzeichnung | Flammable Liquid |
| Brandgefahren | Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as ammonia, nitrogen oxides, and carbon monoxide, may be formed when involved in fire.Flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 32 °C explosive vapour/air mixtures may be formed. |
| Brandpotenzial | ...A DANGEROUS FIRE HAZARD... |
| Gesundheitsgefahren | Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights. (USCG, 1999) |
| Gefahrenübersicht | Has potential to cause corneal damage[ACGIH] |
Anwendungen & Verwendung
Verwenden
N-Ethylmorpholine is a component of the buffer used in basic peptide separation through anion-exchange chromatography. Further, it acts as a catalyst in the preparation of polyurethane foam.
Herstellung & Synthese
synthetische
N-Ethylmorpholine is synthesized by the reaction of morpholine with bromoethane.