HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N2-[(Phenylmethoxy)carbonyl]-L-asparagin
Z-ASN-OH · CBZ-ASN-OH · Z-ASN · CBZ-L-ASPARAGINE · CBZ-L-ASN · Z-ASPARAGINE · Nα-Carbobenzoxy-L-asparagine · Z-L-ASN-OH
![Molekülstruktur von N2-[(Phenylmethoxy)carbonyl]-L-asparagin](/img/chemical/75314.png)
Identifikatoren & physikalische Daten
| CAS No. | 2304-96-3 |
|---|---|
| Summenformel | C12H14N2O5 |
| Durchschnittliche Molmasse | 266,25 g/mol |
| Monoisotopische Masse | 266,09027155 g/mol |
| SMILES | NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)O |
| InChIKey | FUCKRCGERFLLHP-VIFPVBQESA-N |
| PubChem CID | 75314 |
| EC No. | 218-969-5 |
| DTXSID | DTXSID90883824 |
| Lokaler Name | N2-[(Phenylmethoxy)carbonyl]-L-asparagin |
Chemische & physikalische Eigenschaften
| XLogP | -0,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 119 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 19 |
| Formalladung | 0 |
| Komplexität | 339 |
| Schmelzpunkt | 163-165 °C(lit.) |
| Siedepunkt | 409.45°C (rough estimate) |
| Dichte | 1.2846 (rough estimate) |
| Brechungsindex | 6.3 ° (C=1.6, AcOH) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Löslichkeit | almost transparency in hot Methanol |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 3.77±0.10(Predicted) |
| Farbe | White to Almost white |
| BRN | 3085452 |
| InChIKey | FUCKRCGERFLLHP-VIFPVBQESA-N |
| CAS Datenbank | 2304-96-3(CAS DataBase Reference) |
| EPA chemische Informationen | L-Asparagine, N2-[(phenylmethoxy)carbonyl]- (2304-96-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (3 of 3) of all reports.Not ClassifiedAggregated GHS information provided per 3 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Not Classified |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29242990 |
| R-Sätze (R) | 20/21/22-36/37/38 |
| Gefahrensymbole | Xi,Xn |
| Sicherheitshinweise (S) | 24/25-36-26 |
| Gefahrenklasse | IRRITANT |
Anwendungen & Verwendung
Verwenden
Nα-Cbz-L-asparagine is an N-Cbz-protected form of L-Asparagine (A790005). L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.