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N,N-Dimethylglyciniumchlorid
N,N-DIMETHYLGLYCINE HCL · DIMETHYLGLYCINE HCL · DIMETHYL GLYCINE HYDROCHLORIDE · 2-(DIMETHYLAMINO)ACETIC ACID HYDROCHLORIDE · DMG HYDROCHLORIDE · H-GLY(2ME)-OH HCL · IFLAB-BB F1929-1772 · N,N-DIMETHYL-GLY-OH HCL
Identifikatoren & physikalische Daten
| CAS No. | 2491-06-7 |
|---|---|
| Summenformel | C4H9NO2.ClH |
| Durchschnittliche Molmasse | 139,58 g/mol |
| Monoisotopische Masse | 139,04000624 g/mol |
| SMILES | CN(C)CC(=O)O.Cl |
| InChIKey | FKASAVXZZLJTNX-UHFFFAOYSA-N |
| PubChem CID | 75605 |
| EC No. | 219-648-2 |
| DTXSID | DTXSID1062463 |
| Lokaler Name | N,N-Dimethylglyciniumchlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 40,5 |
|---|---|
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 70,1 |
| Schmelzpunkt | 189-194 °C(lit.) |
| Siedepunkt | 397.74℃[at 101 325 Pa] |
| Dichte | 1.326[at 20℃] |
| Dampfdruck | 0Pa at 25℃ |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | DMSO: 10 mg/mlPBS (pH 7.2): 10 mg/ml100 g/L (20 ºC) |
| Aggregatzustand | Crystalline Powder |
| Farbe | White |
| Geruch | Slight to none |
| Merck | 14,3244 |
| BRN | 3910578 |
| InChI | 1S/C4H9NO2.ClH/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)1H |
| InChIKey | FKASAVXZZLJTNX-UHFFFAOYSA-N |
| SMILES | [Cl-].N(CC(=O)O)(C)C.[H+] |
| LogP (Verteilungskoeffizient) | -0.3 |
| CAS Datenbank | 2491-06-7(CAS DataBase Reference) |
| EPA chemische Informationen | Glycine, N,N-dimethyl-, hydrochloride (2491-06-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 36.4% (4 of 11) of reports.WarningH315 (54.5%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 11 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Glycine, N,N-dimethyl-, hydrochlorideStatus: Cease Manufacture Update: 22-11-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/21092Glycine, N,N-dimethyl-, hydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29212900 |
| RTECS-Nr. | MB9995000 |
| R-Sätze (R) | 36/37/38 |
| Sicherheitshinweise (S) | 22-24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. Used in the development of glycine-based ionic liquids and emulsifiers. Also it is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).