Dodecyldihydrogenphosphat

Lauryl Phosphate

HCID 75816CAS 2627-35-2

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Grundinformationen

Standard-SMILES: CCCCCCCCCCCCOP(=O)(O)O
InChIKey: TVACALAUIQMRDF-UHFFFAOYSA-N
Summenformel: C12H27O4P
Durchschnittliche Molmasse: 266,31 g/mol
Monoisotopische Masse: 266,16469597

Überblick

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

Namen und Bezeichner

Bevorzugter Name: Lauryl Phosphate
IUPAC: dodecyl dihydrogen phosphate
Lokaler Name: Dodecyldihydrogenphosphat
Englischer Name: Dodecyl dihydrogen phosphate
Summenformel: C12H27O4P
Molmasse: 266.31

Namen und Synonyme

Dodecyl dihydrogen phosphate2627-35-2Lauryl phosphateMonolauryl phosphateMonododecyl phosphateDihydrogen monolauryl phosphatePhosphoric acid, monododecyl esterLauryl dihydrogen phosphate0K08L8GE2HEINECS 220-095-4lauryl monophosphaten-dodecyl phosphate

Weitere Namen anzeigen

mono-n-DodecyLDODECYL PHOSPHATELauryl acid phosphatemono-lauryl phosphateChrome mist inhibitorDODECYLPHOSPHORIC ACIDMONO-DODECYL PHOSPHATEMONO-N-DODECYL PHOSPHATEDodecyldihydrogenphosphat

NSC 41919DODECYL ACID PHOSPHATEROMOL MAP HDODECANYL PHOSPHATENIKKOL PHOSTEN HLPNSC-41919PHOSPHANOL ML-200ETHFAC 102

Datenbank-Bezeichner

CAS: 2627-35-2
PubChem CID: 75816
DTXSID: DTXSID70880492
ChEMBL: CHEMBL187711
UNII: 0K08L8GE2H
EC Number: 220-095-4
Nikkaji: J192.141J

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 4
Polarare Oberfläche (TPSA): 66,8 Å²
H-Brücken-Donoren: 2
H-Brücken-Akzeptoren: 4
Frei drehbare Bindungen: 12
Schwere Atome: 17
Formalladung: 0
Komplexität: 203

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Classes -> Organophosphates, Other

Cosmetics · 2 Einträge

Cosmetic ingredients (Lauryl Phosphate) -> CIR (Cosmetic Ingredient Review)

Emulsifying

Physical DescriptionWhite odorless crystals; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt: 39 · 39-45°C
Siedepunkt: 385.5 · 385.5±25.0 °C(Predicted)
Dichte: 1.056 · 1.056±0.06 g/cm3(Predicted)
pka: 1.95 · 1.95±0.10(Predicted)
Aggregatzustand: White to off-white solid.
Wasserlöslichkeit: Insoluble in water.
BRN: 1710518 · 1710518
InChI: 1S/C12H27O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H2,13,14,15)
InChIKey: TVACALAUIQMRDF-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCOP(O)(O)=O
CAS Datenbank: 2627 · 2627-35-2(CAS DataBase Reference)
EPA chemische Informationen: Monolauryl phosphate (2627-35-2)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H314 (14.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: Phosphoric acid, monododecyl ester

Phosphoric acid, monododecyl ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryPowder causes eye irritation; [Alfa Aesar MSDS] See Monooctyl phosphate.

Hazard Classes and CategoriesSkin Corr. 1B (14.3%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk: WGK 2
tsca: TSCA listed
ridadr: 3261
risk_code: 36/37/38-43-41-37/38
hazard_code: Xi
safety_code: 26-36/37/39-45
Speicherklasse: 10 - Combustible liquids
Hazard Classifications: Eye Dam. 1Skin Irrit. 2Skin Sens. 1STOT SE 3

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: Lauryl Phosphate

Use ClassificationCosmetics -> Emulsifying

General Manufacturing InformationPhosphoric acid, monododecyl ester: ACTIVE

Anwendungen

Verwendenmono-n-Dodecyl phosphate is a lysophosphatidic acid (LPA) receptor ligand which serves as a specific agonist at EDG-4 (LPA2) (EC50=700 nM) and antagonist at EDG-7