2-Dibutylamino-ethanol

2-(Dibutylamino)ethanol

HCID 7621CAS 102-81-8

Grundinformationen

Standard-SMILES
CCCCN(CCO)CCCC
InChIKey
IWSZDQRGNFLMJS-UHFFFAOYSA-N
Summenformel
C10H23NO
Durchschnittliche Molmasse
173,3 g/mol
Monoisotopische Masse
173,17796436

Überblick

Dibutylaminoethanol is a colorless liquid with a mild fishlike odor. Flash point 200 °F. Toxic by ingestion and skin absorption. Used to make other chemicals.

Namen und Bezeichner

Bevorzugter Name
2-(Dibutylamino)ethanol
IUPAC
2-(dibutylamino)ethanol
Lokaler Name
2-Dibutylamino-ethanol
Englischer Name
2-(Dibutylamino)ethanol
Summenformel
C10H23NO
Molmasse
173.3

Namen und Synonyme

2-(DIBUTYLAMINO)ETHANOL102-81-8N,N-Dibutylethanolamine2-N-DibutylaminoethanolDibutylaminoethanolEthanol, 2-(dibutylamino)-DibutylethanolamineBU2AE2-Di-n-butylaminoethanolN,N-di-n-ButylaminoethanolN,N-Dibutyl-2-hydroxyethylamineN,N-Dibutyl-N-(2-hydroxyethyl)amine
Weitere Namen anzeigen
DBAE2-(DibutyLDibutylethanolamin2-Dibutyaminoethanol2-(DIBUTYLAMINO)ETHA
beta-N-Dibutylaminoethyl alcoholDTXSID20249533IT10X9MHOn,n-dibutylaminoethanolNSC-6330EXTENDEX 30DTXCID904953N-(2-HYDROXYETHYL)DIBUTYLAMINE

Datenbank-Bezeichner

CAS
102-81-8
PubChem CID
7621
DTXSID
DTXSID2024953
ChEMBL
CHEMBL1447214
UNII
3IT10X9MHO
EC Number
203-057-1
Nikkaji
J78.150I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2,1
Polarare Oberfläche (TPSA)
23,5 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
8
Schwere Atome
12

Experimentelle und physikochemische Eigenschaften

Chemical Classes · 2 Einträge

Nitrogen Compounds -> Ethanolamines

Flammable agents - 2nd degree

Density · 4 Einträge

0.85 (NTP, 1992) - Less dense than water; will float

Relative density (water = 1): 0.9

0.86

0.86

Solubility · 3 Einträge

less than 1 mg/mL at 64 °F (NTP, 1992)

Solubility in water at 20 °C: poor

0.4%

Flash Point · 5 Einträge

210 °F (NTP, 1992)

210 °F

90 °C c.c.

195 °F

195 °F

Boiling Point · 4 Einträge

435 to 450 °F at 760 mmHg (NTP, 1992)

222-232 °C

446 °F

446 °F

Melting Point-70 °C

Physikochemische Eigenschaften

Schmelzpunkt
-70 °C · -70°C(lit.)
Siedepunkt
229 · 229-230 °C(lit.)
Dichte
0.86 g/mL · 0.86 g/mL at 25 °C(lit.)
Dampfdichte
6 · 6 (vs air)
Dampfdruck
5 Pa · 5Pa at 20℃
Brechungsindex
20 · n20/D 1.444(lit.)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H302 (87.5%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 273 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H227: Combustible liquid [Warning Flammable liquids]

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: Ethanol, 2-(dibutylamino)-

Ethanol, 2-(dibutylamino)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-(dibutylamino)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 17-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5336

2-N-Dibutylaminoethanol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelPoison
Fire Hazards · 3 Einträge

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

· Combustible material: may burn but does not ignite readily.

Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 90 °C explosive vapour/air mixtures may be formed.

Health Hazards · 2 Einträge

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

· TOXIC and/or CORROSIVE; inhalation, ingestion or skin contact with material may cause severe injury or death.

Hazards Summary · 1 Eintrag

In animals: irritation of eyes, skin, and nose; corneal necrosis; weight loss; [NIOSH] Molten substance may cause severe burns; [CAMEO] May be corrosive to skin and eyes based on animal results; [CHEMINFO] DBAE is an irritant of the nose and eyes. Animal studies show that DBAE inhibits acetylcholinesterase. The median lethal dose in rats dying of respiratory arrest is 89.1 mg/kg. Five rats with inhalation exposures of 33 ppm 6 hours a day for 5 days had no mortality. [ACGIH]

DOT ID and Guide · 2 Einträge

2873 153

2873 153

Sicherheit und Schutzausrüstung

Fire Fighting · 2 Einträge

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.

First Aid Measures · 4 Einträge

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .

Accidental Release Measures · 2 Einträge

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 3 Einträge

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

General First Aid:

(General first aid procedures)

Safe StorageSeparated from strong acids, oxidants, metals and food and feedstuffs. Well closed. Ventilation along the floor.
Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).

Toxikologische Informationen

Target OrgansEyes, skin, respiratory system
Adverse EffectsDermatotoxin - Skin burns.
Exposure Routes · 2 Einträge

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

inhalation, skin absorption, ingestion, skin and/or eye contact

Signs and Symptoms · 5 Einträge

Cough. Sore throat. Nausea. Convulsions. Dizziness. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconsciousness.

MAY BE ABSORBED! Skin burns. Pain. Redness. See Inhalation.

Pain. Redness. Severe deep burns.

Abdominal pain. Burning sensation. Shock or collapse. Abdominal cramps. Diarrhoea. Vomiting. See Inhalation.

In Animals: irritation eyes, skin, nose; dermatitis; skin, corneal necrosis; weight loss

ICSC Environmental DataThe substance is harmful to aquatic organisms.

Sicherheitsdaten

OEB
A
OEL
TWA: 2 ppm (14 mg/m3) [skin]
wgk
1
tsca
TSCA listed
ridadr
UN 2873
hs_code
2922.19.9690

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

Used as a curing agent for polyurethane foams and silicone resins; a conditioner for cellulose acetate filaments; a corrosion inhibitor in lubricants and hydraulic fluids; and in the synthesis of other organic compounds; [ACGIH]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry]

U.S. Production2023: 1,000,000 - <8,500,000 lb
Industry UsespH regulating agent
General Manufacturing Information · 2 Einträge

Fabricated Metal Product Manufacturing

Ethanol, 2-(dibutylamino)-: ACTIVE

Anwendungen · 1 Eintrag

Verwenden2-(Dibutylamino)ethanol (DBAE) may be used as a coreactant to enhance the electrochemiluminescence (ECL) of tris(2,2′-bipyridyl)ruthenium(II) [Ru(bpy)32+], employed in the ECL immunoassays and DNA probe assays. DBAE may also be used as a catalyst during the synthesis of protected D-erythro-(2S,3R)-sphingosine.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]
上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

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