Hexamethyldisilathian
HEXAMETHYLDISILATHIANE · 1,1,1,3,3,3-HEXAMETHYLDISILATHIANE · Hexamethyldisilthian · DK269 · athiane · NSC 252160 · HEXAMETHYLDISILTHIANE · hexamethyl-disilathian
Identifikatoren & physikalische Daten
| CAS No. | 3385-94-2 |
|---|---|
| Summenformel | C6H18SSi2 |
| Durchschnittliche Molmasse | 178,44 g/mol |
| Monoisotopische Masse | 178,06677482 g/mol |
| SMILES | C[Si](C)(C)S[Si](C)(C)C |
| InChIKey | RLECCBFNWDXKPK-UHFFFAOYSA-N |
| PubChem CID | 76920 |
| EC No. | 222-201-4 |
| DTXSID | DTXSID2063006 |
| Lokaler Name | Hexamethyldisilathian |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 25,3 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 76 |
| Kovats Retention Index | 993 |
| Siedepunkt | 164 °C(lit.) |
| Dichte | 0.846 g/mL at 25 °C(lit.) |
| Brechungsindex | n20/D 1.4586(lit.) |
| Flammpunkt | 79 °F |
| Lagerbedingungen | Flammables area |
| Löslichkeit | Miscible with terahydrofuran and toluene.Soluble in tetrahydrofuran and toluene. Hydrolyzes in water. |
| Aggregatzustand | Liquid |
| Wichte | 0.851 |
| Farbe | Colorless |
| BRN | 1740046 |
| Stabilität | store cold |
| InChI | 1S/C6H18SSi2/c1-8(2,3)7-9(4,5)6/h1-6H3 |
| InChIKey | RLECCBFNWDXKPK-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)S[Si](C)(C)C |
| CAS Datenbank | 3385-94-2(CAS DataBase Reference) |
| EPA chemische Informationen | Disilathiane, hexamethyl- (3385-94-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH226 (97.8%): Flammable liquid and vapor [Warning Flammable liquids]H301 (84.8%): Toxic if swallowed [Danger Acute toxicity, oral]H311 (84.8%): Toxic in contact with skin [Danger Acute toxicity, dermal]H315 (13%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (13%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H331 (84.8%): Toxic if inhaled [Danger Acute toxicity, inhalation]H335 (13%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Flam. Liq. 3 (97.8%)Acute Tox. 3 (84.8%)Skin Irrit. 2 (13%)Eye Irrit. 2 (13%)STOT SE 3 (13%) |
| F | 10-13-21 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1993 3/PG 3 |
| Zollcode | 29319090 |
| R-Sätze (R) | 10-23/24/25 |
| Gefahrensymbole | T |
| Sicherheitshinweise (S) |
Anwendungen & Verwendung
Verwenden
Bis(trimethylsilyl) sulfide (TMS2S) is used to reduce aromatic nitro groups to amines and the oxides of sulfur, selenium, and tellurium. Conditions for nitro group reduction (eq 1) are forcing; however, yields are good. Reactions of TMS2S with primary aliphatic nitro groups result in the formation of the thiohydroxamic acids (eq 2) which can be isolated or carried further to the nitrile. Secondary alkyl nitro derivatives provide oximes. Sulfoxides are reduced to sulfides, selenoxides to selenides, and telluroxides to tellurides. Conditions are mild and work well on both the aliphatic and aromatic oxides.