HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Methoxyquinolin-8-amine
5-METHOXYQUINOLIN-8-AMINE · 5-methoxy-8-quinolinamine · 5-methoxy-8-aminoquinoline · 8-AMINO-5-METHOXYQUINOLINE · 8-QuinolinaMine, 5-Methoxy- · 5-METHOXY-QUINOLIN-8-YLAMINE · 8-Amino-5-methoxyquinoline 95%
Identifikatoren & physikalische Daten
| CAS No. | 30465-68-0 |
|---|---|
| Summenformel | C10H10N2O |
| Durchschnittliche Molmasse | 174,2 g/mol |
| Monoisotopische Masse | 174,07931294 g/mol |
| SMILES | COc1ccc(N)c2ncccc12 |
| InChIKey | MFLLTRMMFHENCM-UHFFFAOYSA-N |
| PubChem CID | 777110 |
| EC No. | 842-342-0 |
| DTXSID | DTXSID50354621 |
Chemische & physikalische Eigenschaften
| XLogP | 1,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 48,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 174 |
| Schmelzpunkt | 90-95°C |
| Siedepunkt | 355.7±27.0 °C(Predicted) |
| Dichte | 1.217±0.06 g/cm3(Predicted) |
| Lagerbedingungen | under inert gas (nitrogen or Argon) at 2–8 °C |
| pKa (Säurekonstante) | 3.98±0.12(Predicted) |
| Aggregatzustand | powder |
| InChI | InChI=1S/C10H10N2O/c1-13-9-5-4-8(11)10-7(9)3-2-6-12-10/h2-6H,11H2,1H3 |
| InChIKey | MFLLTRMMFHENCM-UHFFFAOYSA-N |
| SMILES | N1C2C(=C(OC)C=CC=2N)C=CC=1 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | WGK 3 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp3)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.