HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dinatrium-4-nitrophenylphosphat
PNPP · 4-NPP · sodiuM 4-nitrophenyl phosphate · 4-PNPP · ABTS<PNPP-NA2 · PNPP, 2NA · 2-oxazole · PNPP di-NA
Identifikatoren & physikalische Daten
| CAS No. | 4264-83-9 |
|---|---|
| Summenformel | C6H4NNa2O6P |
| Durchschnittliche Molmasse | 263,05 g/mol |
| Monoisotopische Masse | 262,95716241 g/mol |
| SMILES | O=[N+]([O-])c1ccc(OP(=O)([O-])[O-])cc1.[Na+].[Na+] |
| InChIKey | VIYFPAMJCJLZKD-UHFFFAOYSA-L |
| PubChem CID | 77949 |
| EC No. | 224-246-5 |
| DTXSID | DTXSID3063380 |
| Lokaler Name | Dinatrium-4-nitrophenylphosphat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 118 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 16 |
| Formalladung | 0 |
| Komplexität | 238 |
| Stoffklassen | Nitrogen Compounds -> Nitrophenols |
| Physical Description | Hexahydrate: Solid[Sigma-Aldrich MSDS] |
| Schmelzpunkt | >300 °C(lit.) |
| Dichte | 1.751 at 20℃ |
| Dampfdruck | 15Pa at 20-50℃ |
| Lagerbedingungen | -20°C |
| Löslichkeit | H2O: 1 tablet/3 mL 25 mM, clear, light yellowMiscible with water. Immiscible with ethanol and acetone. |
| Aggregatzustand | tablets |
| Farbe | white to pale yellow |
| BRN | 5324661 |
| Stabilität | Stable, but may be light sensitive. Incompatible with strong acids, strong bases, strong oxidizing agents. |
| InChI | 1S/C6H6NO6P.2Na/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H2,10,11,12)/q2*+1/p-2 |
| InChIKey | KAKKHKRHCKCAGH-UHFFFAOYSA-L |
| SMILES | [Na+].[Na+].[P](=O)([O-])([O-])Oc1ccc(cc1)[N+](=O)[O-] |
| LogP (Verteilungskoeffizient) | -2.16 at 22℃ and pH6.7 |
| Oberflächenspannung | 69.34mN/m at 1.051g/L and 20℃ |
| CAS Datenbank | 4264-83-9(CAS DataBase Reference) |
| EPA chemische Informationen | Phosphoric acid, mono(4-nitrophenyl) ester, disodium salt (4264-83-9) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 40% (2 of 5) of reports.WarningH302 (60%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Phosphoric acid, mono(4-nitrophenyl) ester, disodium saltREACH registered substance: Disodium 4-nitrophenyl phosphate (EC: 224-246-5)Phosphoric acid, mono(4-nitrophenyl) ester, disodium salt: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | May cause irritation[Sigma-Aldrich MSDS] See 4-Nitrophenol. |
| Hazard Classes and Categories | Acute Tox. 4 (60%) |
| F | 10-21 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29199000 |
| R-Sätze (R) | 36/38-36/37/38-48/22-41-38-21/22 |
| Gefahrensymbole | Xi,Xn |
| Sicherheitshinweise (S) | 26-36-24/25-23-36/37/39 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
PNPP, Disodium Salt is a colorimetric alkaline phosphatase soluble substrate, p-Nitrophenyl Phosphate (pNPP) is the substrate of choice for use with alkaline phosphatase in Enzyme Linked Immunosorbant Assay (ELISA) procedures.