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Bromcyclobutan
BROMOCYCLOBUTANE · obutane · Cyclobutyl halide · CYCLOBUTYL BROMIDE · Cyclobutane,bromo- · Cyclobutane, bromo- · BroMocyclobutane 96% · Bromocyclobutane,95%
Identifikatoren & physikalische Daten
| CAS No. | 4399-47-7 |
|---|---|
| Summenformel | C4H7Br |
| Durchschnittliche Molmasse | 135 g/mol |
| Monoisotopische Masse | 133,97311232 g/mol |
| SMILES | BrC1CCC1 |
| InChIKey | KXVUSQIDCZRUKF-UHFFFAOYSA-N |
| PubChem CID | 78110 |
| EC No. | 224-530-9 |
| DTXSID | DTXSID20196010 |
| Lokaler Name | Bromcyclobutan |
Chemische & physikalische Eigenschaften
| XLogP | 1,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 30,6 |
| SpringerMaterials Properties | Schoenflies notation |
| Siedepunkt | 108 °C(lit.) |
| Dichte | 1.434 g/mL at 25 °C(lit.) |
| Brechungsindex | n20/D 1.479(lit.) |
| Flammpunkt | 72 °F |
| Lagerbedingungen | Keep in dark place,Sealed in dry,2-8°C |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly)Insoluble |
| Aggregatzustand | Liquid |
| Farbe | Clear colorless |
| BRN | 1900415 |
| InChI | InChI=1S/C4H7Br/c5-4-2-1-3-4/h4H,1-3H2 |
| InChIKey | KXVUSQIDCZRUKF-UHFFFAOYSA-N |
| SMILES | C1(Br)CCC1 |
| CAS Datenbank | 4399-47-7(CAS DataBase Reference) |
| NIST chemische Informationen | Cyclobutyl bromide(4399-47-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 49 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Flam. Liq. 2 (100%) |
| F | 8 |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 1993 3/PG 2 |
| Zollcode | 29038900 |
| R-Sätze (R) | 10-36/37/38-20/21/22 |
| Gefahrensymbole | Xi,Xn |
| Sicherheitshinweise (S) | 26-36-36/37/39-16 |
| Gefahrenklasse | 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | II |
| Lagerklasse | 3 - Flammable liquids |
Anwendungen & Verwendung
Verwenden
Cyclobutyl bromide is a cyclopentyl compound that has an hydroxyl group. It is a potent inhibitor of the CB2 receptor, which is primarily expressed on cells of the immune system. Cyclobutyl bromide has been shown to inhibit the uptake of uv light and also has anti-inflammatory properties. Studies have confirmed that this drug inhibits the production of cytokines and chemokines in chronic bronchitis patients, as well as other inflammatory diseases such as rheumatoid arthritis.