HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl-4-nitronaphthylether
methyl4-nitronaphthylether · 1-Methoxy-4-nitronaphthalin · 4-Methoxy-1-nitronaphthalene · 1-METHOXY-4-NITRONAPHTHALENE · 1-Nitro-4-methoxynaphthalene · Naphthalene,1-methoxy-4-nitro- · 1-Methoxy-4-nitronaphthalene 99% · 1-Methoxy-4-nitronaphthalene,99%
Identifikatoren & physikalische Daten
| CAS No. | 4900-63-4 |
|---|---|
| Summenformel | C11H9NO3 |
| Durchschnittliche Molmasse | 203,197 g/mol |
| Monoisotopische Masse | 203,05824315 g/mol |
| SMILES | COc1ccc([N+](=O)[O-])c2ccccc12 |
| InChIKey | YFJKGPRYPHFGQD-UHFFFAOYSA-N |
| PubChem CID | 78613 |
| EC No. | 225-528-0 |
| DTXSID | DTXSID20197663 |
| Lokaler Name | Methyl-4-nitronaphthylether |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 83-85 °C (lit.) |
|---|---|
| Siedepunkt | 341.49°C (rough estimate) |
| Dichte | 1.2621 (rough estimate) |
| Brechungsindex | 1.4950 (estimate) |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| InChI | InChI=1S/C11H9NO3/c1-15-11-7-6-10(12(13)14)8-4-2-3-5-9(8)11/h2-7H,1H3 |
| InChIKey | YFJKGPRYPHFGQD-UHFFFAOYSA-N |
| SMILES | C1(OC)=C2C(C=CC=C2)=C([N+]([O-])=O)C=C1 |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-37/39 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
1-Methoxy-4-nitronaphthalene is used as a reagent in the synthesis of UMI-77 (U700850); a small molecule inhibitor of Mcl-1 which blocks and attenuates pancreatic cell cancer growth. Also an anticancer agent.