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Biuret
BIURET REAGENT · IMIDODICARBONIC DIAMIDE · Dicarbonimidic diamide · iuret · Allophamicacidamide · L-101 · biure · BIURET
Identifikatoren & physikalische Daten
| CAS No. | 108-19-0 |
|---|---|
| Summenformel | C2H5N3O2 |
| Durchschnittliche Molmasse | 103,08 g/mol |
| Monoisotopische Masse | 103,03817641 g/mol |
| SMILES | NC(=O)NC(N)=O |
| InChIKey | OHJMTUPIZMNBFR-UHFFFAOYSA-N |
| PubChem CID | 7913 |
| ChEMBL | CHEMBL1889026 |
| ChEBI | CHEBI:18138 |
| EC No. | 203-559-0 |
| DTXSID | DTXSID2026783 |
| Lokaler Name | Biuret |
Chemische & physikalische Eigenschaften
| XLogP | -0,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 98,2 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 87,1 |
| Stoffklassen | Nitrogen Compounds -> Other Nitrogen Compounds |
| Arzneimittel | Pharmaceuticals -> Metabolite of Metformin |
| SpringerMaterials Properties | 15N nuclear magnetic resonance spectrum |
| Geruch | ODORLESS |
| Dichte | 1.467 @ -5 °C/4 °C1.01 g/mL at 20 °C |
| Color/Form | ELONGATED PLATES FROM ETHANOLNEEDLES FROM WATER CRYSTALLIZING WITH 1 MOLECULE OF WATER PER MOLECULE OF COMPDWHITE NEEDLES |
| Löslichkeit | SOL IN 100 G WATER: 2.01 G @ 25 °C, 7 G @ 50 °C, 20 G @ 75 °C, 53.5 G @ 105.5 °CFREELY SOL IN ALCOHOLVERY SLIGHTLY SOL IN ETHERDMSO (Slightly), Methanol (Slightly, Heated, Sonicated)2 g/100 mL (25 ºC) |
| Schmelzpunkt | 190 °C, DECOMP185-190 °C (dec.) (lit.) |
| Physical Description | CBIWhite hygroscopic solid[HSDB] White odorless powder[Alfa Aesar MSDS] |
| Other Experimental Properties | HYGROSCOPICPYROLYSIS @ HIGH TEMP (GREATER THAN 193 °C) YIELDS MELAMINEWHEN CRYSTALLIZED FROM WATER, 5C2-H5-N3-O2.4H20 IS FORMED, WHICH BECOMES ANHYDROUS @ 110 °C, DECOMP @ ABOUT 193 °CAQ SOLN TREATED WITH CUPRIC SULFATE & SODIUM HYDROXIDE GIVE REDDISH-VIOLET COLOR |
| Siedepunkt | 100 °C |
| Brechungsindex | 1.4264 (estimate) |
| Lagerbedingungen | 2-8°C |
| pKa (Säurekonstante) | 10.17±0.46(Predicted) |
| Aggregatzustand | Liquid |
| Farbe | White |
| Geruch | Odorless |
| Merck | 14,1309 |
| BRN | 1703510 |
| Stabilität | Stable. Incompatible with strong oxidizing agents, strong bases. Hygroscopic. |
| InChI | 1S/C2H5N3O2/c3-1(6)5-2(4)7/h(H5,3,4,5,6,7) |
| InChIKey | OHJMTUPIZMNBFR-UHFFFAOYSA-N |
| SMILES | NC(=O)NC(N)=O |
| CAS Datenbank | 108-19-0(CAS DataBase Reference) |
| NIST chemische Informationen | Imidodicarbonic diamide(108-19-0) |
| EPA chemische Informationen | Imidodicarbonic diamide (108-19-0) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 135 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Imidodicarbonic diamideImidodicarbonic diamide is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Imidodicarbonic diamide are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Imidodicarbonic diamide: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | Mildly bacteriostatic and diuretic in ratsAlso causes drop in blood pressure, marked urinary tract irritation, and increases in pepsin activity[Merck Index] A skin and strong eye irritant[Alfa Aesar MSDS] |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Explosive Limits and Potential | DURING CHLORINATION OF IMPURE BIURET IN WATER @ 20 °C, A VIOLENT EXPLOSION OCCURRED. THIS WAS ATTRIBUTED TO CONVERSION OF THE CYANURIC ACID IMPURITY (3%) TO NITROGEN TRICHLORIDE & SPONTANEOUS EXPLOSION OF THE LATTER. |
| Non-Human Toxicity Excerpts | HAS WEAK...DIURETIC PROPERTIES IN RATS, ALSO CAUSES A FALL IN BLOOD PRESSURE, BUT PRODUCES STRONG IRRITATION OF URINARY TRACT. INCREASES THE ACTIVITY OF PEPSIN....TOXIC TO SOME CROPS... |
| RAIS Toxicity Values | 0.0045CALEPA0.0004 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29241990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36/37-36 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrstoffdaten | 108-19-0(Hazardous Substances Data) |
Anwendungen & Verwendung
Verwenden
Biuret is used in protein assay. It is also used as Catalytic agent, Petrochemical additive. It is used in organic synthesis. Biuret (Carbamoylurea) was used as a source of dietary nitrogen in purified diets for steers.