HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Ethylpiperazin
N-ETHYLPIPERAZINE · NEPRZ · 1-Ethylperazine · N-Ethylpiperazin · 1-ETHYLPIPERAZINE · ETHYLPIPERAZINE-N · AKOS BBS-00003610 · 1-ethyl-piperazin
Identifikatoren & physikalische Daten
| CAS No. | 5308-25-8 |
|---|---|
| Summenformel | C6H14N2 |
| Durchschnittliche Molmasse | 114,19 g/mol |
| Monoisotopische Masse | 114,11569845 g/mol |
| SMILES | CCN1CCNCC1 |
| InChIKey | WGCYRFWNGRMRJA-UHFFFAOYSA-N |
| PubChem CID | 79196 |
| EC No. | 226-166-6 |
| DTXSID | DTXSID8073346 |
| Lokaler Name | 1-Ethylpiperazin |
Chemische & physikalische Eigenschaften
| XLogP | 0 |
|---|---|
| Polarare Oberfläche (TPSA) | 15,3 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 57,5 |
| SpringerMaterials Properties | Refractive index |
| Schmelzpunkt | -60 °C |
| Siedepunkt | 157 °C(lit.) |
| Dichte | 0.899 g/mL at 25 °C(lit.) |
| Dampfdruck | 2.48hPa at 20℃ |
| Brechungsindex | n20/D 1.469(lit.) |
| Flammpunkt | 110 °F |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | soluble |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | 9.27±0.10(Predicted) |
| Wichte | 0.899 |
| Farbe | Clear colorless to yellow |
| BRN | 102971 |
| InChI | 1S/C6H14N2/c1-2-8-5-3-7-4-6-8/h7H,2-6H2,1H3 |
| InChIKey | WGCYRFWNGRMRJA-UHFFFAOYSA-N |
| SMILES | CCN1CCNCC1 |
| LogP (Verteilungskoeffizient) | -0.1 at 20℃ |
| CAS Datenbank | 5308-25-8(CAS DataBase Reference) |
| NIST chemische Informationen | N-ethylpiperazine(5308-25-8) |
| EPA chemische Informationen | Piperazine, 1-ethyl- (5308-25-8) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 275 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 12-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/317391-Ethylpiperazine: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 3 (100%) |
| F | 10-34 |
| Wassergefährdungsklasse (WGK) | 1 |
| UN-Transportnummer | UN 1993 3/PG 3 |
| Zollcode | 29335995 |
| RTECS-Nr. | TM0815500 |
| R-Sätze (R) | 36/37/38-10 |
| Gefahrensymbole | Xi,Hazard |
| Sicherheitshinweise (S) | 26-36 |
| Gefahrenklasse | 3Acute Tox. 4 OralEye Dam. 1Flam. Liq. 3Skin Corr. 1BSkin Sens. 1BSTOT SE 3 |
| Verpackungsgruppe | III |
| Lagerklasse | 3 - Flammable liquids |
Anwendungen & Verwendung
Verwenden
1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.