Propylene Carbonate

Identifikatoren & physikalische Daten

CAS No.	108-32-7
Summenformel	C4H6O3
Durchschnittliche Molmasse	102,09 g/mol
Monoisotopische Masse	102,03169405 g/mol
SMILES	CC1COC(=O)O1
InChIKey	RUOJZAUFBMNUDX-UHFFFAOYSA-N
PubChem CID	7924
ChEMBL	CHEMBL1733973
ChEBI	CHEBI:231185
EC No.	203-572-1
DTXSID	DTXSID2026789

Chemische & physikalische Eigenschaften

XLogP	-0,4
Polarare Oberfläche (TPSA)	35,5
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	3
Frei drehbare Bindungen	0
Schwere Atome	7
Formalladung	0
Komplexität	88,9
Stoffklassen	Other Classes -> Other Organic Compounds
Kosmetika	Cosmetic ingredients (Propylene Carbonate) -> CIR (Cosmetic Ingredient Review)Viscosity controllingSolvent
LogP (Verteilungskoeffizient)	log Kow = -0.41
Geruch	OdorlessWeak odor
Dichte	1.2047 g/cu cm at 20 °C1.2047 @ 20°C1.2047 g/cm3
Color/Form	Colorless liquidClear, colorless liquid
Löslichkeit	In water, 1.75X10+5 mg/L at 25 °CVery soluble in ethanol, ether, acetone, benzeneMiscible with chloroform and ethyl acetatemoderately soluble in carbon tetrachloride
Flammpunkt	116 °C (241 °F) - closed cup275 °F (135 °C) (closed cup)
Animal Drugs	Pharmaceuticals -> UK Veterinary Medicines Directorate List
Siedepunkt	241.6 °C242 °C @760 [mm Hg]
Decomposition	When heated to decomposition it emits acrid smoke and irritating fumes.
Schmelzpunkt	-48.8 °C

Sicherheit & Vorschriften

GHS-Einstufung	WarningH319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for < 0.1% (2 of 4143) of reports.H319 (> 99.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Regulatorische Informationen	Chemical: 1,3-Dioxolan-2-one, 4-methyl-1,3-Dioxolan-2-one, 4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3-Dioxolan-2-one, 4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 07-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/16088Propylene carbonate: Does not have an individual approval but may be used under an appropriate group standard
Brandpotenzial	Combustible when exposed to heat or flame.
Gefahrenübersicht	Causes somnolence in subcutaneous, lethal-dose studies of rats and miceA moderate skin irritant[RTECS] An irritant[MSDSonline]
FDA-Anforderungen	Propylene carbonate is an indirect food additive for use only as a component of adhesives.
Special Reports	AnonymousFinal Report on the Safety Assessment of Propylene Carbonate. J Am Coll Toxicol 6 (1): 23-51 (1987). The toxicologic properties of propylene carbonate were reviewed, with emphasis on the use of propylene carbonate as a cosmetic ingredient. Topics included chemical properties, physical properties, and cosmetic and noncosmetic uses of propylene carbonate. Propylene carbonate has been used as a polar additive for montmorillonite or bentonite clay gellants, widely used as bases for antiperspirants, lipstick, skin cleansers, eye shadow, mascara, hair conditioners, and other products. ...
EPA Safer Chemical	Chemical: Propylene carbonate
FIFRA-Anforderungen	Unless specifically excluded, residues resulting from the use of the following substance as either an inert or an active ingredient in a pesticide chemical formulation, including antimicrobial pesticide chemicals, is exempted from the requirement of a tolerance under FFDCA section 408, if such use is in accordance with good agricultural or manufacturing practices. 1,3-Dioxolan-2-one, 4-methyl- is included on this list.