HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Amino-2-chlorpyridin
6-CHLOROPYRIDIN-3-AMINE · 6-CHLORO-PYRIDIN-3-YLAMINE · AMINO CHLOROPYRIDINE · 6-chloro-3-pyridinamine · 3-AMINO-6-CHLOROPYRIDINE · Tobrasix · 5-Amino-2-chL · TIMTEC-BB SBB004234
Identifikatoren & physikalische Daten
| CAS No. | 5350-93-6 |
|---|---|
| Summenformel | C5H5ClN2 |
| Durchschnittliche Molmasse | 128,56 g/mol |
| Monoisotopische Masse | 128,01412584 g/mol |
| SMILES | Nc1ccc(Cl)nc1 |
| InChIKey | QAJYCQZQLVENRZ-UHFFFAOYSA-N |
| PubChem CID | 79305 |
| ChEBI | CHEBI:194601 |
| EC No. | 226-322-3 |
| DTXSID | DTXSID40201716 |
| Lokaler Name | 5-Amino-2-chlorpyridin |
Chemische & physikalische Eigenschaften
| XLogP | 1,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 38,9 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 76,8 |
| Schmelzpunkt | 81-83 °C(lit.) |
| Siedepunkt | 205.39°C (rough estimate) |
| Dichte | 1.2417 (rough estimate) |
| Brechungsindex | 1.5110 (estimate) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Room temperature |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 1.94±0.10(Predicted) |
| Farbe | White to Brown |
| BRN | 108891 |
| InChI | InChI=1S/C5H5ClN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2 |
| InChIKey | QAJYCQZQLVENRZ-UHFFFAOYSA-N |
| SMILES | C1=NC(Cl)=CC=C1N |
| CAS Datenbank | 5350-93-6(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 77 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29333999 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36-37/39 |
| Gefahrenklasse | IRRITANTEye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.