Grundinformationen
- Standard-SMILES
Cc1cccc(Cl)c1- InChIKey
OSOUNOBYRMOXQQ-UHFFFAOYSA-N- Summenformel
- C7H7Cl
- Durchschnittliche Molmasse
- 126,58 g/mol
- Monoisotopische Masse
- 126,0236279
Überblick
M-chlorotoluene is a colorless liquid. Specific gravity 1.072. Denser than water, thus sinks in water. Flash point less than 141 °F. Vapors irritating and narcotic in high concentrations. Used as solvents and as an intermediate for making other chemicals and dyes.
Namen und Bezeichner
- Bevorzugter Name
- 3-Chlorotoluene
- IUPAC
- 1-chloro-3-methylbenzene
- Lokaler Name
- Chlortoluol (m)
- Englischer Name
- 3-Chlorotoluene
- Summenformel
- C7H7Cl
- Molmasse
- 126.58
Namen und Synonyme
3-Chlorotoluene108-41-81-Chloro-3-methylbenzeneM-CHLOROTOLUENEm-Tolyl chloride3-Chloro-1-methylbenzeneBenzene, 1-chloro-3-methyl-Toluene, m-chloro-1-Methyl-3-chlorobenzene3-METHYLCHLOROBENZENE5K8172K9TTNSC-8767
Weitere Namen anzeigen
MCTMETA CHLORO TOLUENE3-Chlortoluolm-ChlortoluolM-Chlorotoluenm-Tolylchloride3-Chlorobenzene
M-METHYLCHLOROBENZENEDTXSID4052841RefChem:93547DTXCID607852203-580-5meta-Chlorotoluene1-chloranyl-3-methyl-benzeneNSC 8767
Datenbank-Bezeichner
- CAS
108-41-8- PubChem CID
- 7931
- DTXSID
DTXSID4052841- ChEMBL
CHEMBL1797289- UNII
- 5K8172K9TT
- EC Number
- 203-580-5
- Nikkaji
- J1.497D
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,3
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 0
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 8
- Formalladung
- 0
- Komplexität
- 70,8
Experimentelle und physikochemische Eigenschaften
SolventsSolvents -> Chlorinated Aromatics
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
Density1.0722 at 68 °F (USCG, 1999) - Denser than water; will sink
Flash Point
126 °F (NTP, 1992)
126 °F
Boiling Point324 °F at 760 mmHg (NTP, 1992)
Melting Point-54 °F (NTP, 1992)
Vapor Pressure
10 mmHg at 109.8 °F (NTP, 1992)
3.68 [mmHg]
Physical Description
M-chlorotoluene is a colorless liquid. Specific gravity 1.072. Denser than water, thus sinks in water. Flash point less than 141 °F. Vapors irritating and narcotic in high concentrations. Used as solvents and as an intermediate for making other chemicals and dyes.
Colorless liquid; [Hawley]
Physikochemische Eigenschaften
- Schmelzpunkt
- -48 °C · -48 °C (lit.)
- Siedepunkt
- 160 · 160-162 °C (lit.)
- Dichte
- 1.072 g/mL · 1.072 g/mL at 25 °C (lit.)
- Dampfdruck
- 3.6 mbar · 3.6 mbar @ 20 C
- Brechungsindex
- 20 · n20/D 1.522(lit.)
- Flammpunkt
- 123 °F · 123 °F
- storage temp.
- 0 · 0-6°C
- Löslichkeit
- 0.04 g/l · 0.04g/l
- Aggregatzustand
- Liquid
- Farbe
- Clear colorless to slightly yellow
- Explosionsgrenze
- 1.3 · 1.3-8.3%(V)
- Wasserlöslichkeit
- slightly soluble
- Merck
- 14 · 14,2171
- BRN
- 1903632 · 1903632
- Henry's Law Constant
- 6.1 · 6.1×10-4 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
- Dielectric constant
- 5.55 · 5.5499999999999998
- Stabilität
- Stable. Flammable. Incompatible with strong oxidizing agents.
- InChI
- 1S/C7H7Cl/c1-6-3-2-4-7(8)5-6/h2-5H,1H3
- InChIKey
- OSOUNOBYRMOXQQ-UHFFFAOYSA-N
- SMILES
- Cc1cccc(Cl)c1
- CAS Datenbank
- 108 · 108-41-8(CAS DataBase Reference)
- NIST chemische Informationen
- 1 · Benzene, 1-chloro-3-methyl-(108-41-8)
- EPA chemische Informationen
- m-Chlorotoluene (108-41-8)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H332: Harmful if inhaled [Warning Acute toxicity, inhalation]
P261, P271, P273, P304+P340, P317, P391, and P501 (click each P-code to see the statement)
Warning
H226 (95.5%): Flammable liquid and vapor [Warning Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P317, P321, P330, P332+P317, P362+P364, P370+P378, P391, P403+P235, and P501 (click each P-code to see the statement)
Gefahrenhinweise
Regulatory Information
Chemical: Benzene, 1-chloro-3-methyl-
Status: Active Update: 07-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19214
3-Chlorotoluene: Does not have an individual approval but may be used under an appropriate group standard
DOT LabelFlammable Liquid
Fire HazardsSpecial Hazards of Combustion Products: May contain toxic chloride fumes.
Health HazardsInhalation causes upper respiratory irritation. Irritating to skin and eyes. May be absorbed through the skin. Prolonged exposure may result in systemic toxic effects. Harmful if swallowed. (USCG, 1999)
Hazards SummaryA skin, eye, and respiratory tract irritant; [CAMEO] Causes narcosis in high concentrations; [Hawley] Harmful by inhalation; [MSDSonline]
Reactive GroupAryl Halides
Reactivity AlertsHighly Flammable
Reactivity ProfileM-CHLOROTOLUENE is generally unreactive. May be incompatible with strong oxidizing and reducing agents. May be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Air and Water ReactionsFlammable. Slightly soluble in water.
Hazard Classes and Categories
Flam. Liq. 3 (95.5%)
Acute toxicity - category 4
Flammable liquids - Category 3
Acute Tox. 4 *
Lower Explosive Limit (LEL)1.36 % (calculated) (USCG, 1999)
Sicherheit und Schutzausrüstung
Fire FightingExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill ResponseExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
Isolation and EvacuationExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
Personal Protective Equipment (PPE)Wear self-contained positive pressure breathing apparatus and full protective clothing. (USCG, 1999)
Toxikologische Informationen
Adverse EffectsNeurotoxin - Acute solvent syndrome
Sicherheitsdaten
- wgk
- 2
- tsca
- TSCA listed
- ridadr
- UN 2238 3/PG 3
- hs_code
- 29039990
- RTECS-Nr.
- XS8990000
- risk_code
- 20-51/53
- hazard_code
- Xn,N
- safety_code
- 24/25-61
- hazard_class
- 3
- packing_group
- III
- Speicherklasse
- 3 - Flammable liquids
- Hazard Classifications
- Acute Tox. 4 InhalationAquatic Chronic 2Flam. Liq. 3
Chemie und Industrie
Verwendung und Herstellung
UsesUsed as a solvent and to make other chemicals and dyes; [CAMEO]
General Manufacturing InformationBenzene, 1-chloro-3-methyl-: ACTIVE
Anwendungen
Verwenden3-Chlorotoluene was used as catalyst in the synthesis of glycidyl methacrylate grafted multi-walled carbon nanotubes/polypropylene nanocomposites. It was used to study paramagnetic contributions from dioxygen to solute proton spin-lattice relaxation rate constants for a series of aromatic hydrocarbons and drug molecule fragments.
Darstellung
synthetische3-Chlorotoluene is obtained from m-toluidine by diazotization and substitution. Add m-toluidine to water, slowly add concentrated hydrochloric acid, and add sodium nitrite solution dropwise at 0-5°C. Then the diazo solution is added to the cuprous chloride for replacement reaction. The crude product generated is distilled to obtain the finished product. If the diazo salt is made into a zinc chloride complex salt of m-toluidine diazo salt, it is decomposed by reflux in ether, and the reactants are cooled, washed and dried. After recovering the ether, it is distilled at atmospheric pressure and m-chlorotoluene is obtained by collecting 160-162°C fraction. The advantage of this method is that the diazonium salt is not easy to hydrolyze and generate phenols.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Nachgelagerte Produkte
Anbieter50 Anbieter
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
江苏星科元信息科技有限公司400-605-7200 15335295587
山东前元高分子材料有限公司18678041314 18765609661 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Hangzhou Verychem Science And Technology Co.Ltd+86-86-57188162785 +8613606544505 · [email protected]
武汉捷又顺化工科技有限公司18062118104; 18062118104
Syntechem Co.,Ltd[email protected]
上海辅欣医药科技有限公司+86-021-021-50872116 · [email protected]
江苏普乐司生物科技有限公司0513-66017706 18551496367 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
艾科试剂4008-755-333 18080918076 · [email protected]
上海思域化工科技有限公司86-21-34053660 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
卡迪亚医药科技有限公司0371-86615086 18203638366 0371-86159066 13526786601
上海倍卓生物科技有限公司021-61119791,13386096464 · [email protected]
北京环宇世纪化学科技有限公司hysj_bj.com
安徽科迪达化工有限公司0554-2106669 · [email protected]
日照力德士化工有限公司010-51268198 · [email protected]
美岚实业（上海）有限公司021-58958189 · [email protected]
上海爱蝶实业有限公司021-58957966 18930537195 · [email protected]
广拓化学（上海）有限公司021-60899189-8001 18918189673 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
上海纳谦化学科技有限公司13598610367 13598610367 · [email protected]
上海嵩爰化工科技有限公司010-1234567 18521000990 · [email protected]
武汉弘德悦欣医药科技有限公司027-83855396 15271852016
成都润泽本土化工有限公司13096311329 028-88469284 616445927 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
潍坊市前进精细化工有限公司18753684562 · [email protected]
郑州科豫隆化工产品有限公司17319789407 17319789407 · [email protected]
Zugehörige Reaktionen
24
Verknüpfte Notizen
Wird geladen…