HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Piperidin-4-ol
PIPERIDIN-4-OL · 4-PIPERIDINOL · 4PPOL · 4-piperidinyl · AURORA KA-1006 · Piperidine-4α-ol · Piperidine-4β-ol · 4-Hydropiperidine
Identifikatoren & physikalische Daten
| CAS No. | 5382-16-1 |
|---|---|
| Summenformel | C5H11NO |
| Durchschnittliche Molmasse | 101,15 g/mol |
| Monoisotopische Masse | 101,08406397 g/mol |
| SMILES | OC1CCNCC1 |
| InChIKey | HDOWRFHMPULYOA-UHFFFAOYSA-N |
| PubChem CID | 79341 |
| ChEMBL | CHEMBL284022 |
| EC No. | 226-373-1 |
| DTXSID | DTXSID10202098 |
| Lokaler Name | Piperidin-4-ol |
Chemische & physikalische Eigenschaften
| XLogP | -0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 32,3 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 50 |
| Stoffklassen | Nitrogen Compounds -> Amino Alcohols, Other |
| Physical Description | Hygroscopic solid[Alfa Aesar MSDS] |
| Schmelzpunkt | 86-90 °C |
| Siedepunkt | 108-114 °C/10 mmHg (lit.) |
| Dichte | 0.9903 (rough estimate) |
| Dampfdruck | 13Pa at 25℃ |
| Brechungsindex | 1.4400 (estimate) |
| Flammpunkt | 226 °F |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Room temperature |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly)soluble |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 14.94±0.20(Predicted) |
| Farbe | Off-White to pale Yellow |
| pH | 11.5-11.7 (H2O)Aqueous solution |
| BRN | 102738 |
| InChI | 1S/C5H11NO/c7-5-1-3-6-4-2-5/h5-7H,1-4H2 |
| InChIKey | HDOWRFHMPULYOA-UHFFFAOYSA-N |
| SMILES | OC1CCNCC1 |
| LogP (Verteilungskoeffizient) | -0.35 at 25℃ |
| CAS Datenbank | 5382-16-1(CAS DataBase Reference) |
| NIST chemische Informationen | 4-Hydroxypiperidine(5382-16-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH314 (24.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 78 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: 4-PiperidinolStatus: Active Update: 03-10-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/208574-Piperidinol: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | Causes burnsInhalation may cause corrosive injuries to upper respiratory tract and lungs[Alfa Aesar MSDS] |
| Hazard Classes and Categories | Skin Corr. 1B (24.4%) |
| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | 3263 |
| Zollcode | 29333999 |
| R-Sätze (R) | 36/37/38-34 |
| Gefahrensymbole | Xi,C |
| hazard_note | Irritant |
| Sicherheitshinweise (S) | 26-36-37/39-45-36/37/39-27 |
| Gefahrenklasse | 8Eye Irrit. 2Skin Irrit. 2 |
| Verpackungsgruppe | III |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
4-Hydroxypiperidine is used as a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.