4-Methylmorpholin
4-Methylmorpholine
Grundinformationen
- CAS
109-02-4- Standard-SMILES
CN1CCOCC1- InChIKey
SJRJJKPEHAURKC-UHFFFAOYSA-N- Summenformel
- C5H11NO
- Durchschnittliche Molmasse
- 101,15 g/mol
- Monoisotopische Masse
- 101,08406397
Überblick
4-methylmorpholine appears as a water-white liquid with an ammonia-like odor. Less dense than water and insoluble in water. May be moderately toxic by ingestion, inhalation and skin absorption. Very irritating to skin, eyes, and mucous membranes. Used as a solvent and to make pharmaceuticals.
Namen und Bezeichner
- Bevorzugter Name
- 4-Methylmorpholine
- IUPAC
- 4-methylmorpholine
- Lokaler Name
- 4-Methylmorpholin
- Englischer Name
- 4-Methylmorpholine
- Summenformel
- C5H11NO
- Molmasse
- 101.15
Namen und Synonyme
4-MethylmorpholineN-METHYLMORPHOLINE109-02-4Morpholine, 4-methyl-1-MethylmorpholineDTXSID902914611P91ANU5XNSC-9382DTXCID709146RefChem:99901203-640-0Methylmorpholine
Weitere Namen anzeigen
4-methyl-morpholinN-Methyl morphofinen-methyl-morpholinMorpholine,4-methyl-N-MethylMorpholine, 99% 100GR
N-methyl morpholineMorpholine, N-methyl-4-MethylmorfolinN-MethylmorpholinN-methylmopholineNSC 93824-methyl-morpholineNMM
Datenbank-Bezeichner
- CAS
109-02-4- PubChem CID
- 7972
- DTXSID
DTXSID9029146- ChEMBL
CHEMBL2448839- UNII
- 11P91ANU5X
- EC Number
- 203-640-0
- Nikkaji
- J100.752A
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -0,3
- Polarare Oberfläche (TPSA)
- 12,5 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 50
Experimentelle und physikochemische Eigenschaften
Chemical Classes
Nitrogen Compounds -> Morpholines
Flammable agents - 3rd degree
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
LogP-0.33
Density0.9 @25 °C
Flash Point
75 °F (NFPA, 2010)
75 °F
Boiling Point115 °C @760 [mm Hg]
Vapor Pressure13.2 [mmHg]
Physical Description
4-methylmorpholine appears as a water-white liquid with an ammonia-like odor. Less dense than water and insoluble in water. May be moderately toxic by ingestion, inhalation and skin absorption. Very irritating to skin, eyes, and mucous membranes. Used as a solvent and to make pharmaceuticals.
Liquid
A water-white liquid with an ammonia-like odor; [CAMEO]
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 2% (14 of 715) of reports.
Danger
H225 (89.1%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 715 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
Gefahrenhinweise
Regulatory Information
Chemical: Morpholine, 4-methyl-
Morpholine, 4-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Morpholine, 4-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: 4-methylmorpholine (EC: 203-640-0)
Morpholine, 4-methyl-: HSNO Approval: HSR001392 Approved with controls
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
DOT LabelFlammable Liquid Corrosive
Fire Hazards
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:
· Flammable/combustible material.
· Flammable/combustible material.
Health Hazards
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:
Chemie und Industrie
Verwendung und Herstellung
Uses
Used as a solvent and to make pharmaceuticals. [CAMEO] Used in poyurethane foam production; [Reference #1]
Plastic Composites Manufacturing [Category: Industry]
U.S. Production2023: 1,000,000 - <2,500,000 lb
Consumer UsesCatalyst
Industry UsesCatalyst
General Manufacturing Information
Petroleum Refineries
Morpholine, 4-methyl-: ACTIVE
Darstellung
synthetische4-Methylmorpholine preparation method is to slowly add formaldehyde in morpholine drop by drop, under stirring add formic acid reaction, automatic reflux, and release carbon dioxide. After adding formic acid, heating reflux 4 ~ 5h, cooling and adding sodium hydroxide immediately distillation, collect all the fraction before the boiling point of 99 ℃, and then add sodium hydroxide in the fraction to saturation, cooling the oil layer, drying, fractional distillation, to obtain N-methylmorpholine.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
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