HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(1-Ethyl-1H-benzimidazol-2-yl)methanol
Albb-003786 · (1-Ethyl-2-benzimidazolyl)methanol · (1-ethylbenzimidazol-2-yl)methanol · 1H-BENZIMIDAZOLE-2-METHANOL, 1-ETHYL- · 1H-Benzimidazole-2-methanol,1-ethyl-(9CI) · (1-Ethyl-1H-benzo[d]imidazol-2-yl)methanol · (1-ethylbenzimidazol-2-yl)methanol - [E84822] · (1-ethyl-1H-benzimidazol-2-yl)methanol(SALTDATA: FREE)
Identifikatoren & physikalische Daten
| CAS No. | 21269-78-3 |
|---|---|
| Summenformel | C10H12N2O |
| Durchschnittliche Molmasse | 176,21 g/mol |
| Monoisotopische Masse | 176,094963 g/mol |
| SMILES | CCn1c(CO)nc2ccccc21 |
| InChIKey | YPMCFIDLEKUBHI-UHFFFAOYSA-N |
| PubChem CID | 799599 |
| EC No. | 696-395-8 |
| DTXSID | DTXSID60355407 |
Chemische & physikalische Eigenschaften
| XLogP | 0,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 38,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 174 |
| Schmelzpunkt | 143 °C |
| Siedepunkt | 357.5±25.0 °C(Predicted) |
| Dichte | 1.18±0.1 g/cm3(Predicted) |
| Lagerbedingungen | Store at room temperature |
| pKa (Säurekonstante) | 13.81±0.10(Predicted) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (50%) |
| Alarmwort | Warnung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315 |
Anwendungen & Verwendung
Verwenden
1-Ethyl-2-hydroxymethylbenzimidazole is an intermediate used in the synthesis of N-pyrimidinyl-4-aminobenzenesulfonamides useful for treatment or prevention of disease mediated by α2B-adrenoceptor. It is also used to prepare benzimidazole derivatives as ENaC blockers.