HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Methoxyethylamin
2-Methoxyethanamine · 2-AMINOETHYL METHYL ETHER · Methyl-PEG-amine · Methoxyethylamine · Ethanamine, 2-methoxy- · CAS_109-85-3 · CH3OCH2CH2NH2 · 2-methoxy-ethylamin
Identifikatoren & physikalische Daten
| CAS No. | 109-85-3 |
|---|---|
| Summenformel | C3H9NO |
| Durchschnittliche Molmasse | 75,11 g/mol |
| Monoisotopische Masse | 75,06841391 g/mol |
| SMILES | COCCN |
| InChIKey | ASUDFOJKTJLAIK-UHFFFAOYSA-N |
| PubChem CID | 8018 |
| ChEMBL | CHEMBL4101550 |
| EC No. | 203-712-1 |
| DTXSID | DTXSID1021908 |
| Lokaler Name | 2-Methoxyethylamin |
Chemische & physikalische Eigenschaften
| XLogP | -0,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 35,3 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 16,4 |
| Stoffklassen | Nitrogen Compounds -> Other Nitrogen Compounds |
| SpringerMaterials Properties | Coriolis coupling |
| Siedepunkt | 95 °C @760 [mm Hg]95 °C (lit.) |
| Physical Description | Clear colorless liquid[Sigma-Aldrich MSDS] |
| Schmelzpunkt | -82 °C |
| Dichte | 0.864 g/mL at 25 °C (lit.) |
| Brechungsindex | n20/D 1.406(lit.) |
| Flammpunkt | 49 °F |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | Completely miscible in water |
| Aggregatzustand | clear liquid |
| pKa (Säurekonstante) | 9.89(at 10℃) |
| Farbe | Colorless to Almost colorless |
| pH | 12 (100g/l, H2O, 20℃) |
| Explosionsgrenze | 3-16.10%(V) |
| BRN | 741854 |
| Henry-Konstante | 2.5×101 mol/(m3Pa) at 25℃, Cabani et al. (1978) |
| InChI | 1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3 |
| InChIKey | ASUDFOJKTJLAIK-UHFFFAOYSA-N |
| SMILES | COCCN |
| CAS Datenbank | 109-85-3(CAS DataBase Reference) |
| EPA chemische Informationen | Ethanamine, 2-methoxy- (109-85-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 156 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | 2-Methoxyethylamine: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | A severe eye irritantCauses muscle weakness, tremor, ataxia, dyspnea, and cyanosis in oral lethal-dose studies of rats and mice[RTECS] Causes burnsInhalation may cause corrosive injuries to upper respiratory tract and lungs[Sigma-Aldrich MSDS] See Ethanolamine. |
| Hazard Classes and Categories | Flam. Liq. 2 (100%) |
| Protective Action Criteria (PAC) | 1.3 [mg/m3]14 [mg/m3]87 [mg/m3] |
| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 2733 3/PG 2 |
| Zollcode | 29221990 |
| RTECS-Nr. | KR8750000 |
| R-Sätze (R) | 11-34 |
| Toxizität | LD50 orally in Rabbit: 1570 mg/kg |
| Gefahrensymbole | F,C |
| Sicherheitshinweise (S) | 16-26-36/37/39-45 |
| Gefahrenklasse | 3Acute Tox. 4 InhalationAcute Tox. 4 OralEye Dam. 1Flam. Liq. 2Skin Corr. 1B |
| Verpackungsgruppe | II |
| Lagerklasse | 3 - Flammable liquids |
| Selbstentzündungstemperatur | 285 °C |
Anwendungen & Verwendung
Verwenden
2-Methoxyethylamine is used as a reagent in the preparation of lipid-like materials for delivery of RNAi therapeutics.