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(+)-2-Aminopropan-1-ol
L-ALANINOL · (S)-2-AMINO-1-PROPANOL · (S)-(+)-2-AMINO-1-PROPANOL · 2-AMINOPROPANOL · 310399 · H-ALA-OL · L-2-Amino-1-propanol · Ala-OL
Identifikatoren & physikalische Daten
| CAS No. | 2749-11-3 |
|---|---|
| Summenformel | C3H9NO |
| Durchschnittliche Molmasse | 75,11 g/mol |
| Monoisotopische Masse | 75,06841391 g/mol |
| SMILES | C[C@H](N)CO |
| InChIKey | BKMMTJMQCTUHRP-VKHMYHEASA-N |
| PubChem CID | 80307 |
| ChEMBL | CHEMBL1229871 |
| ChEBI | CHEBI:78502 |
| EC No. | 220-388-7 |
| DTXSID | DTXSID901347737 |
| Lokaler Name | (+)-2-Aminopropan-1-ol |
Chemische & physikalische Eigenschaften
| XLogP | -1 |
|---|---|
| Polarare Oberfläche (TPSA) | 46,3 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 22,9 |
| Stoffklassen | Nitrogen Compounds -> Amino Alcohols, Other |
| SpringerMaterials Properties | Optical coefficient |
| Physical Description | Clear viscous liquid[Sigma-Aldrich MSDS] |
| Schmelzpunkt | -2°C |
| Siedepunkt | 72-73 °C11 mm Hg(lit.) |
| Dichte | 0.965 g/mL at 25 °C(lit.) |
| Brechungsindex | n20/D 1.450 |
| Flammpunkt | 145 °F |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,2-8°C |
| Löslichkeit | Completely miscible in waterChloroform, Methanol (Slightly) |
| pKa (Säurekonstante) | 12.88±0.10(Predicted) |
| Aggregatzustand | Oily Liquid |
| Wichte | 0.96 |
| Farbe | Clear colorless to yellow |
| BRN | 1718865 |
| InChI | 1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m0/s1 |
| InChIKey | BKMMTJMQCTUHRP-VKHMYHEASA-N |
| SMILES | C[C@H](N)CO |
| CAS Datenbank | 2749-11-3(CAS DataBase Reference) |
| NIST chemische Informationen | 1-Propanol, 2-amino-, (S)-(2749-11-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 204 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 08-06-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/17701 |
| Gefahrenübersicht | Causes burnsInhalation may cause corrosive injuries to upper respiratory tract and lungs[Sigma-Aldrich MSDS] |
| Hazard Classes and Categories | Skin Corr. 1B (100%) |
| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
| F | 10-23 |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 2735 8/PG 2 |
| Zollcode | 29221990 |
| R-Sätze (R) | 34-36/37/38 |
| Gefahrensymbole | C,Xi |
| Sicherheitshinweise (S) | 26-36/37/39-45-36 |
| Gefahrenklasse | 8Skin Corr. 1B |
| Verpackungsgruppe | III |
| Lagerklasse | 8A - Combustible corrosive hazardous materials |
Anwendungen & Verwendung
Verwenden
S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are of ten used as ligands in homogeneous catalysis.