Pentylamine (HCID 8060)

Überblick

N-amylamine appears as a clear colorless liquid with an ammonia-like odor. Irritates the eyes and respiratory system. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a corrosion inhibitor, solvent, flotation agent and in the manufacture of other chemicals.

Namen und Bezeichner

Bevorzugter Name: Pentylamine
IUPAC: pentan-1-amine
Lokaler Name: Pentylamin
Englischer Name: Amylamine
Summenformel: C5H13N
Molmasse: 87.16

Namen und Synonyme

AmylaminePentylamine110-58-7pentan-1-amine1-Aminopentane1-PentylamineN-AMYLAMINE1-Pentanaminen-PentylamineMonoamylamineNorleucamineE05QM3V8EF

Weitere Namen anzeigen

PentylaminAMYLAMINESAmylaminAMINE C5

NSC-7906DTXSID0021919FEMA NO. 4242CHEBI:74848RefChem:171523DTXCID801919203-780-2932-628-4

Datenbank-Bezeichner

CAS: 110-58-7
PubChem CID: 8060
DTXSID: DTXSID0021919
ChEBI: CHEBI:74848
UNII: E05QM3V8EF
EC Number: 203-780-2、932-628-4、935-734-9
Nikkaji: J1.978J

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 1,5
Polarare Oberfläche (TPSA): 26 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 3
Schwere Atome: 6
Formalladung: 0
Komplexität: 19,9

Experimentelle und physikochemische Eigenschaften

Chemical Classes · 2 Einträge

Nitrogen Compounds -> Amines, Aliphatic

Corrosives

DrugsPharmaceuticals -> Listed in ZINC15

SpringerMaterials PropertiesBoiling point

Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food

Density · 2 Einträge

0.7547 (NTP, 1992) - Less dense than water; will float

0.750-0.759

Flavoring AgentsEU Flavoring substances

Physikochemische Eigenschaften

Schmelzpunkt: 55 °C · −55 °C(lit.)
Siedepunkt: 104 °C · 104 °C(lit.)
Dichte: 0.752 g/mL · 0.752 g/mL at 25 °C(lit.)
Dampfdichte: 3.01 · 3.01 (vs air)
Dampfdruck: 120.9 hPa · 120.9 hPa (47 °C)
FEMA: 4242 · 4242 | PENTYLAMINE
Brechungsindex: 20 · n20/D 1.411(lit.)
Flammpunkt: 42 °F · 42 °F
storage temp.: Flammables area
Löslichkeit: Soluble in alcohol, ether.
pka: 10.63 · 10.63(at 25℃)
Aggregatzustand: Liquid
Farbe: Clear colorless to very slightly yellow
Geruch (Odor): 0.1 % · at 0.10 % in propylene glycol. ammoniacal fishy
Geruchsart: fishy
Biologische Quelle: synthetic
Explosionsgrenze: 2.2 · 2.2-22%(V)
Wasserlöslichkeit: soluble
Spezifische Wärmekapazität: 2.5 J/ · Cp(liquid): 2.5 J/(g·K), at 25℃
Merck: 14 · 14,598
JECFA Number: 1585 · 1585
BRN: 505953 · 505953
Henry's Law Constant: 4.3 · 4.3×10-1 mol/(m3Pa) at 25℃, Brockbank (2013)
Dielectric constant: 4.6 · 4.6(22℃)
Major Application: flavors and fragrances
InChI: 1S/C5H13N/c1-2-3-4-5-6/h2-6H2,1H3
InChIKey: DPBLXKKOBLCELK-UHFFFAOYSA-N
SMILES: CCCCCN
LogP: 1.49 · 1.49
CAS Datenbank: 110 · 110-58-7(CAS DataBase Reference)
NIST chemische Informationen: 1 · 1-Pentanamine(110-58-7)
EPA chemische Informationen: Amylamine (110-58-7)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 171 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: 1-Pentanamine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Status: Active Update: 09-02-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/11243

Amylamine: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelFlammable Liquid Corrosive

Fire Hazards · 2 Einträge

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

· Flammable/combustible material.

Health Hazards · 2 Einträge

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

· May cause toxic effects if inhaled or ingested.

Hazards Summary · 1 Eintrag

Corrosive to skin; [Quick CPC] A severe irritant; [NTP] Safe when used as a flavoring agent in food; [JECFA] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS]

DOT ID and Guide1106 132

Sicherheit und Schutzausrüstung

Fire FightingExcerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Accidental Release Measures · 2 Einträge

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 2 Einträge

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

General First Aid:

Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).

Nonfire Spill ResponseExcerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Isolation and Evacuation · 2 Einträge

Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:

Immediate precautionary measure

Toxikologische Informationen

Adverse EffectsDermatotoxin - Skin burns.

Toxicity DataLCLo (rat) = 2,000 ppm/4hr

Sicherheitsdaten

F: 34
wgk: 3
tsca: TSCA listed
ridadr: UN 1106 3/PG II/III (AMYLAMINE)
hs_code: 29211990
RTECS-Nr.: SC0300000
risk_code: 11-22-34-42/43-20/21/22-52/53
Toxizität: LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 1120 mg/kg
hazard_code: F,C
safety_code: 16-26-36/37/39-45-33-61
hazard_class: 3
packing_group: II
Speicherklasse: 3 - Flammable liquids
Hazard Classifications: Acute Tox. 4 DermalAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Flam. Liq. 2Skin Corr. 1B
Selbstentzündungstemperatur: 305 °C

Chemie und Industrie

Verwendung und Herstellung

UsesUsed as a chemical intermediate, solvent, gasoline additive, and in corrosion inhibitors, dyestuffs, flotation agents, rubber chemicals, insecticides, and pharmaceuticals; [NTP]

Use Classification · 3 Einträge

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

General Manufacturing Information1-Pentanamine: ACTIVE

Anwendungen

VerwendenAmylamine is a general reagent used in functionalizing the target molecules with pentyl chain. It has also been used as a cosurfactant to increase the phase stability of the bilayer systems.