Grundinformationen
- Standard-SMILES
C1=COCCC1- InChIKey
BUDQDWGNQVEFAC-UHFFFAOYSA-N- Summenformel
- C5H8O
- Durchschnittliche Molmasse
- 84,12 g/mol
- Monoisotopische Masse
- 84,05751488
Überblick
Dihydro-2h-pyran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Vapors heavier than air.
Namen und Bezeichner
- Bevorzugter Name
- 3,4-dihydro-2H-pyran
- IUPAC
- 3,4-dihydro-2H-pyran
- Lokaler Name
- 3,4-Dihydro-2H-pyran
- Englischer Name
- 3,4-Dihydro-2H-pyran
- Summenformel
- C5H8O
- Molmasse
- 84.12
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
110-87-2、25512-65-6、3174-74-1- PubChem CID
- 8080
- DTXSID
DTXSID6041426- ChEMBL
CHEMBL3184439- UNII
- T6V9N71IHX
- EC Number
- 203-810-4
- Nikkaji
- J43.463I
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,7
- Polarare Oberfläche (TPSA)
- 9,2 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 6
- Formalladung
- 0
- Komplexität
- 57
Experimentelle und physikochemische Eigenschaften
Chemical Classes
Other Classes -> Ethers, Other
Flammable agents - 3rd degree
Physical Description
Dihydro-2h-pyran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Vapors heavier than air.
Liquid
Clear colorless liquid with an ethereal odor; [CAMEO] Unpleasant odor; [Alfa Aesar MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- -70 °C · -70 °C (lit.)
- Siedepunkt
- 86 °C · 86 °C (lit.)
- Dichte
- 0.922 g/mL · 0.922 g/mL at 25 °C (lit.)
- Dampfdichte
- 2.9 · 2.9 (vs air)
- Dampfdruck
- 77.8 hPa · 77.8 hPa (20 °C)
- Brechungsindex
- 20 · n20/D 1.440(lit.)
- Flammpunkt
- 4 °F · 4 °F
- storage temp.
- 30 °C · Store below +30°C.
- Löslichkeit
- 7.7 g/l · 7.7g/l
- Aggregatzustand
- Liquid
- Farbe
- Clear colorless to yellow
- PH
- 7 · 7 (5g/l, H2O, 20℃)
- Explosionsgrenze
- 1.1 · 1.1-13.8%(V)
- Wasserlöslichkeit
- 20 g/L · 20 g/L (20 ºC)
- BRN
- 103493 · 103493
- Stabilität
- Volatile
- InChI
- 1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2
- InChIKey
- BUDQDWGNQVEFAC-UHFFFAOYSA-N
- SMILES
- C1COC=CC1
- LogP
- 0.69 · 0.690
- CAS Datenbank
- 110 · 110-87-2(CAS DataBase Reference)
- NIST chemische Informationen
- 2 H-Pyran, · 2H-Pyran, 3,4-dihydro-(110-87-2)
- EPA chemische Informationen
- 2 H-Pyran, · 2H-Pyran, 3,4-dihydro- (110-87-2)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P272, P280, P302+P352, P303+P361+P353, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 180 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
Gefahrenhinweise
Regulatory Information
Chemical: 2H-Pyran, 3,4-dihydro-
2H-Pyran, 3,4-dihydro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2H-Pyran, 3,4-dihydro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 29-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12042
2H-Pyran, 3,4-dihydro-: HSNO Approval: HSR001129 Approved with controls
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Fire Hazards
Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:
· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Health Hazards
Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:
· Inhalation or contact with material may irritate or burn skin and eyes.
Reactivity Profile
Ethers, such as DIHYDRO-2H-PYRAN, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
DOT Hazard Classification
2,3-Dihydropyran
UN2376
Class 3 Flammable and combustible liquid (49 eCFR § 173.120)
PG II: the degree of danger presented by the material is medium
Hazard Classes and Categories
Flam. Liq. 2 (100%)
Flammable liquids - Category 2
Skin sensitization - Category 1B
Flammable agents - 3rd degree, Reactive agents - 1st degree
Sicherheit und Schutzausrüstung
Accidental Release Measures
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
First Aid
Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:
General First Aid:
Isolation and Evacuation
Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:
Immediate precautionary measure
Protective Action Criteria (PAC)
14 [mg/m3]
150 [mg/m3]
910 [mg/m3]
Toxikologische Informationen
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 2376
- hs_code
- 29329995
- RTECS-Nr.
- UP7700000
- risk_code
- 11-36/37/38-36/38-19
- Toxizität
- LD50 orally in Rabbit: > 4000 mg/kg
- hazard_code
- F,Xi
- hazard_note
- Highly Flammable/Irritant
- safety_code
- 16-26-36-37/39-33-7/9
- hazard_class
- 3
- packing_group
- II
- Speicherklasse
- 3 - Flammable liquids
- Hazard Classifications
- Aquatic Chronic 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2Skin Sens. 1B
- Selbstentzündungstemperatur
- 240 °C
Chemie und Industrie
Verwendung und Herstellung
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
2H-Pyran, 3,4-dihydro-: ACTIVE
Anwendungen
VerwendenWidely used hydroxyl-protecting reagent3,4-Dihydro-2H-pyran is used as a hydroxyl-protecting reagent in organic synthesis. It acts as an intermediate in synthetic chemistry. It is used to protect various reactive functional groups. It is involved in the polymerization reaction either alone or with unsaturated compound and finds application in polymer industries. Further, it is employed in the preparation of bicyclic compounds of epoxide-fused, halo compounds and allenic alcohols.
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