Dodecyltrimethylammonium chloride (HCID 8152)

Überblick

The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Laurtrimonium Chloride...

Namen und Bezeichner

Bevorzugter Name: Dodecyltrimethylammonium chloride
IUPAC: dodecyl(trimethyl)azanium chloride
Lokaler Name: Dodecyltrimethylammoniumchloride
Englischer Name: Dodecyltrimethylammonium chloride
Summenformel: C15H34ClN
Molmasse: 263.89

Namen und Synonyme

Dodecyltrimethylammonium chloride112-00-5DODECYL TRIMETHYL AMMONIUM CHLORIDEDTACAlicopLauryltrimethylammonium chlorideLaurtrimonium chlorideCation BBAliquat 4Dehyquart LTCation FBNissan Cation BB

Weitere Namen anzeigen

LTACTRIMETHYLDODECYLAMMONIUM CHLORIDEN,N,N-Trimethyl-1-dodecanaminium chloride123Caliguat4arguad12

n-Dodecyltrimethylammonium chlorideArquad 12Arquad 12DTrimethyllaurylammonium chlorideCatiogen LNissan Cation FBQuartamin 24PQuartamin 24W

Datenbank-Bezeichner

CAS: 112-00-5
PubChem CID: 8152
DTXSID: DTXSID1026900
ChEMBL: CHEMBL1884887
UNII: A81MSI0FIC
EC Number: 203-927-0

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 0 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 11
Schwere Atome: 17
Formalladung: 0
Komplexität: 135

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Quaternary Amines

Cosmetics · 2 Einträge

Cosmetic ingredients (Laurtrimonium Chloride) -> CIR (Cosmetic Ingredient Review)

Antistatic; Preservative; Emulsifying

Vapor Pressure0.00000001 [mmHg]

Physical Description · 2 Einträge

CBI; Liquid

Solid; [EPA ChAMP: Initial Risk-Based Prioritization Document] White to light yellow powder and chunks; Hygroscopic; [Acros Organics MSDS]

Physikochemische Eigenschaften

Schmelzpunkt: 37 °C · 37 °C
Siedepunkt: 412.12 °C · 412.12°C (rough estimate)
Dichte: 0.9265 · 0.9265 (rough estimate)
Dampfdruck: 0 Pa · 0Pa at 25℃
Brechungsindex: 20 · n20/D 1.426
Flammpunkt: 19 °C · 19 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit: 2 O: · H2O: 50 mg/mL, clear, colorless
Aggregatzustand: Powder or Chunks
Farbe: White to light yellow
PH: 4 to · 4.0 to 7.5(50 g/L, 25 ℃)
Wasserlöslichkeit: Soluble
BRN: 3915951 · 3915951
Stabilität: Stable. Incompatible with strong oxidizing agents. Protect from moisture.
Kosmetik-Inhaltsstoffe Funktionen: PRESERVATIVESURFACTANT - EMULSIFYINGANTISTATIC
InChI: 1S/C15H34N.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1
InChIKey: DDXLVDQZPFLQMZ-UHFFFAOYSA-M
SMILES: [Cl-].CCCCCCCCCCCC[N+](C)(C)C
LogP: 1.22 at · 1.22 at 25℃
Oberflächenspannung: 860 · 860-1710mN/m at 52.78-105.56g/L and 25℃
CAS Datenbank: 112 · 112-00-5(CAS DataBase Reference)
EPA chemische Informationen: Dodecyl trimethyl ammonium chloride (112-00-5)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 2.5% (12 of 476) of reports.

Danger

H302 (87.2%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 476 reports by companies from 28 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: 1-Dodecanaminium, N,N,N-trimethyl-, chloride

1-Dodecanaminium, N,N,N-trimethyl-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Dodecanaminium, N,N,N-trimethyl-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 14-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/24215

1-Dodecanaminium, N,N,N-trimethyl-, chloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Cationic surfactants: Human health tier II assessment

Hazards SummaryIncreased liver weights (with corresponding histopathology) and increased ALT activity in repeated-dose oral studies of animals; [EPA ChAMP: Hazard Characterizations] An irritant; Harmful by ingestion; [Acros Organics MSDS]

Hazard Classes and Categories · 4 Einträge

Acute Tox. 4 (87.2%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Hazardous to the aquatic environment (Acute) - Category 1

Toxikologische Informationen

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Toxicity Summary · 2 Einträge

The CIR Expert Panel concluded the following ingredients are safe in the present practices of use and concentration described in the safety assessment when formulated to be non-irritating...Laurtrimonium Chloride...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

F: 3-10
wgk: 3
tsca: TSCA listed
ridadr: UN 3077 9/PG 3
hs_code: 29239000
RTECS-Nr.: JR2122500
risk_code: 36/37/38-50-50/53-22-67-11
Toxizität: LD50 orally in Rabbit: 200 - 1000 mg/kg
hazard_code: Xi,N,Xn,F
safety_code: 26-61-60-37/39-36-16
hazard_class: 6.1(b)
packing_group: III
Speicherklasse: 13 - Non Combustible Solids
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Eye Irrit. 2Skin Irrit. 2

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties.

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.

Verwendung und Herstellung

Uses · 3 Einträge

CIR ingredient: Laurtrimonium Chloride

Typical uses of category members include surfactants, intermediates, anti-scaling agents, fabric softeners, multifunctional laundry detergents, antistatic sprays, germicides, deodorizers, emulsifiers, hair-care products, industrial lubricants, and corrosion inhibitors; [EPA ChAMP: Initial Risk-Based Prioritization Document]

Using Disinfectants or Biocides [Category: Clean]

U.S. Production2023: 400,000 - <550,000 lb

Consumer UsesCorrosion inhibitor

Industry UsesCBI

Household ProductsInformation on 5 consumer products that contain Laurtrimonium Chloride in the following categories is provided:

Use ClassificationCosmetics -> Antistatic; Preservative; Emulsifying

Anwendungen

VerwendenDodecyltrimethylammonium chloride belongs to quaternary ammonium salts,it is useful as paint strippers, foaming stabilizers, and bactericidal lotions.