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Triglyme
TRIGLYME · TRIETHYLENE GLYCOL DIMETHYL ETHER · 2,5,8,11-TETRAOXADODECANE · 1,2-BIS(2-METHOXYETHOXY)ETHANE · DIMETHYLTRIGLYCOL · glyme4 · Glyme-3 · riglyme
Identifikatoren & physikalische Daten
| CAS No. | 112-49-2 |
|---|---|
| Summenformel | C8H18O4 |
| Durchschnittliche Molmasse | 178,23 g/mol |
| Monoisotopische Masse | 178,12050906 g/mol |
| SMILES | COCCOCCOCCOC |
| InChIKey | YFNKIDBQEZZDLK-UHFFFAOYSA-N |
| PubChem CID | 8189 |
| ChEMBL | CHEMBL1235255 |
| ChEBI | CHEBI:44842 |
| EC No. | 203-977-3 |
| DTXSID | DTXSID8026224 |
Chemische & physikalische Eigenschaften
| XLogP | -0,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 36,9 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 9 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 67,5 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Solvents | Solvents -> Glycol Ethers (Glymes) |
| SpringerMaterials Properties | Dielectric constant |
| Surfactants | Surfactant |
| LogP (Verteilungskoeffizient) | -0.48 |
| Dichte | 0.99 at 68 °F (NTP, 1992) - Less dense than waterwill floatRelative density (water = 1): 0.990.986 @25 °C0.986 g/mL at 25 °C(lit.) |
| Löslichkeit | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)Solubility in water: miscible>1000g/l soluble |
| Flammpunkt | 232 °F (NTP, 1992)111 °C o.c.231 °F |
| Siedepunkt | 421 °F at 760 mmHg (NTP, 1992)216 °C216 °C @760 [mm Hg]216 °C(lit.) |
| Schmelzpunkt | -49 °F (NTP, 1992)-45 °C−45 °C(lit.) |
| Dampfdichte | 4.7 (NTP, 1992) - Heavier than airwill sink (Relative to Air)Relative vapor density (air = 1): 6.14>4.7 (vs air) |
| Dampfdruck | 0.9 mmHg at 68 °F (NTP, 1992)0.04 [mmHg]Vapor pressure, kPa at 20 °C: 0.121.2 hPa (20 °C) |
| Brechungsindex | n20/D 1.423(lit.) |
| Lagerbedingungen | Store below +30°C. |
| Aggregatzustand | Liquid |
| Farbe | APHA: ≤20 |
| pH | 7 |
| Explosionsgrenze | 0.7%(V) |
| Merck | 14,9692 |
| BRN | 1700630 |
| Dielektrizitätskonstante | 7.5 |
| Hauptanwendungen | environmental |
| InChI | 1S/C8H18O4/c1-9-3-5-11-7-8-12-6-4-10-2/h3-8H2,1-2H3 |
| InChIKey | YFNKIDBQEZZDLK-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCOC |
| LogP (Verteilungskoeffizient) | -0.52 at 20℃ |
| Oberflächenspannung | 27.56mN/m at 298.15K |
| CAS Datenbank | 112-49-2(CAS DataBase Reference) |
| NIST chemische Informationen | 2,5,8,11-Tetraoxadodecane(112-49-2) |
| EPA chemische Informationen | Triethylene glycol dimethyl ether (112-49-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH360Df: May damage the unborn childSuspected of damaging fertility [Danger Reproductive toxicity]P203, P280, P318, P405, and P501 (click each P-code to see the statement)H319 (22.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]P203, P264+P265, P280, P305+P351+P338, P318, P337+P317, P405, and P501 (click each P-code to see the statement) |
|---|---|
| Regulatorische Informationen | Chemical: 2,5,8,11-TetraoxadodecaneHazard Traits - Reproductive ToxicityS - indicates a substance that is identified in a final Significant New Use Rule.Status: Active Update: 04-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/10247Substance: 1,2-bis(2-methoxyethoxy)ethane (TEGDMEtriglyme)Triethylene glycol dimethyl ether: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - 2,5,8,11-Tetraoxadodecane: Environment tier I assessment |
| Brandgefahren | This chemical is combustible. (NTP, 1992) |
| Gesundheitsgefahren | SYMPTOMS: Symptoms of exposure to this compound include irritation of the skin and eyes, abdominal pain, coughing, extrasystoles, nausea and vomiting. |
| Gefahrenübersicht | May have adverse effects on human reproduction, based on animal studies[ICSC] Labeled as May impair fertility and May cause harm to the unborn child by EU regulations[Glycol Ethers Online] Prolonged contact with air can form explosive peroxides[CAMEO] A skin and eye irritant[NTP] May form explosive peroxidesAn irritantMay cause impaired fertility and fetal toxicity[Alfa Aesar MSDS] See Monoglyme. |
| Reaktive Gruppe | Ethers |
| EG-Einstufung | Symbol: T |
Anwendungen & Verwendung
Verwenden
Triethylene glycol dimethyl ether is used as a solvent for gases and coupling immiscible liquid. It is also used to prepare perfluoro-triethyleneglycoldimethylether.