N-Methyl-N-(trimethylsilyl)acetamid

N-Trimethylsilyl-N-methylacetamide

HCID 81953CAS 7449-74-3

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Grundinformationen

Standard-SMILES: CC(=O)N(C)[Si](C)(C)C
InChIKey: QHUOBLDKFGCVCG-UHFFFAOYSA-N
Summenformel: C6H15NOSi
Durchschnittliche Molmasse: 145,27 g/mol
Monoisotopische Masse: 145,09229063

Namen und Bezeichner

Bevorzugter Name: N-Trimethylsilyl-N-methylacetamide
IUPAC: N-methyl-N-trimethylsilylacetamide
Lokaler Name: N-Methyl-N-(trimethylsilyl)acetamid
Englischer Name: N-Methyl-N-(trimethylsilyl)acetamide
Summenformel: C6H15NOSi
Molmasse: 145.27

Namen und Synonyme

N-Methyl-N-(trimethylsilyl)acetamide7449-74-3Acetamide, N-methyl-N-(trimethylsilyl)-N-Trimethylsilyl-N-methylacetamideW0IWF6UKW5EINECS 231-217-0NSC 142435NSC-142435DTXSID0064707RefChem:831201DTXCID2047694231-217-0

Weitere Namen anzeigen

MOUSE ALBUMIN[TriMethylsilylating Agent]N-Methyl-N-(trimethylsilyl)amideN-Methyl-N-trimethylsilylacetaminen-methyl-n-(trimethylsilyl)-acetamidAcetamide,N-methyl-N-(trimethylsilyl)-

N-Methyl-N-trimethylsilylacetamideN-Methyl-N-trimethylsilyacetamideN-Methyl-N-TMS-acetamideMFCD00040758N-Methylacetamide, TMS derivatives11925N-Methyl-N-trimethylsilylacetamide (>85%)N-Trimethylsilyl-N-methylacetamide; NSC 142435

Datenbank-Bezeichner

CAS: 7449-74-3
PubChem CID: 81953
DTXSID: DTXSID0064707
UNII: W0IWF6UKW5
EC Number: 231-217-0
Nikkaji: J208.694H

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 20,3 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 1
Schwere Atome: 9
Formalladung: 0
Komplexität: 117

Experimentelle und physikochemische Eigenschaften

SpringerMaterials Properties29Si nuclear magnetic resonance spectrum

Physikochemische Eigenschaften

Siedepunkt: 159 · 159-161 °C(lit.)
Dichte: 0.904 g/mL · 0.904 g/mL at 20 °C(lit.)
Brechungsindex: 20 · n20/D 1.439
Flammpunkt: 48 °C · 48 °C
storage temp.: -20 °C · -20°C
Aggregatzustand: lyophilized powder
pka: -0.11 · -0.11±0.70(Predicted)
Farbe: Clear light yellow
Wichte: 0.906 · 0.906
BRN: 506975 · 506975
InChI: InChI=1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
InChIKey: QHUOBLDKFGCVCG-UHFFFAOYSA-N
SMILES: C(N(C)[Si](C)(C)C)(=O)C
CAS Datenbank: 7449 · 7449-74-3(CAS DataBase Reference)
NIST chemische Informationen: Acetamide, n-methyl-n-(trimethylsilyl)-(7449-74-3)
EPA chemische Informationen: Acetamide, N-methyl-N-(trimethylsilyl)- (7449-74-3)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 5.9% (1 of 17) of reports.

Danger

H226 (94.1%): Flammable liquid and vapor [Warning Flammable liquids]

P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 17 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: Acetamide, N-methyl-N-(trimethylsilyl)-

Status: Active Update: 13-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33411

Hazard Classes and CategoriesFlam. Liq. 3 (94.1%)

Sicherheitsdaten

F: 10-21
wgk: 3
tsca: TSCA listed
ridadr: UN 1993 3/PG 3
hs_code: 29319090
risk_code: 10-36/37/38
hazard_code: Xi
safety_code: 37/39-16
hazard_class: 3
packing_group: III
Speicherklasse: 3 - Flammable liquids
Hazard Classifications: Flam. Liq. 3

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationAcetamide, N-methyl-N-(trimethylsilyl)-: ACTIVE

Anwendungen · 1 Eintrag

VerwendenN-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following: Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique. Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.