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Palmitoyl chloride
Palmitic chloride · HEXADECANOYL CHLORIDE · N-HEXADECANOYL CHLORIDE · mitoyL · Palmitoylchlorid · CETYLOYL CHLORIDE · Palmitoyl choride · PALMITOYL CHLORIDE
Identifikatoren & physikalische Daten
| CAS No. | 112-67-4 |
|---|---|
| Summenformel | C16H31ClO |
| Durchschnittliche Molmasse | 274,9 g/mol |
| Monoisotopische Masse | 274,2063433 g/mol |
| SMILES | CCCCCCCCCCCCCCCC(=O)Cl |
| InChIKey | ARBOVOVUTSQWSS-UHFFFAOYSA-N |
| PubChem CID | 8206 |
| EC No. | 203-996-7 |
| DTXSID | DTXSID4051582 |
Chemische & physikalische Eigenschaften
| XLogP | 7,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 17,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 14 |
| Schwere Atome | 18 |
| Formalladung | 0 |
| Komplexität | 180 |
| Color/Form | COLORLESS LIQUID |
| Löslichkeit | VERY SOL IN ETHERChloroform (Sparingly), Ethyl Acetate (Slightly)Decomposition |
| Siedepunkt | 199 °C @ 20 MM HGBOILING POINT: 194.5 °C AT 17 MM HG88-90 °C/0.2 mmHg (lit.) |
| Schmelzpunkt | 11-12 °C11-13 °C (lit.) |
| Brechungsindex | INDEX OF REFRACTION: 1.4514 @ 20 °C/Dn20/D 1.452(lit.) |
| Physical Description | Hexadecanoyl chloride appears as a clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12 °C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.Clear colorless to light yellow liquidmp = 11-12 deg C[CAMEO] Clear colorless liquidmp = 11-13 deg C[MSDSonline] |
| Other Experimental Properties | DECOMPOSES IN WATER, ALCOHOL |
| Dichte | 0.906 g/mL at 25 °C (lit.) |
| Flammpunkt | >230 °F |
| Lagerbedingungen | Store below +30°C. |
| Aggregatzustand | Liquid |
| Wichte | 0.905 |
| Farbe | Clear |
| BRN | 972409 |
| Stabilität | Moisture Sensitive |
| InChI | 1S/C16H31ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3 |
| InChIKey | ARBOVOVUTSQWSS-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCC(Cl)=O |
| CAS Datenbank | 112-67-4(CAS DataBase Reference) |
| NIST chemische Informationen | Palmitoyl chloride(112-67-4) |
| EPA chemische Informationen | Hexadecanoyl chloride (112-67-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 0.5% (1 of 201) of reports.DangerH290 (21.4%): May be corrosive to metals [Warning Corrosive to Metals]H312 (52.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]H314 (25.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (74.1%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (74.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]P234, P260, P261, P264, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P333+P317, P362+P364, P363, P390, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 201 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 1 of 201 reports by companies.There are 16 notifications provided by 200 of 201 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Hexadecanoyl chlorideStatus: Active Update: 23-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/32158Palmitoyl chloride: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Hexadecanoyl chloride: Human health tier I assessmentIMAP assessments - Hexadecanoyl chloride: Environment tier I assessment |
| DOT-Kennzeichnung | Corrosive |
| Brandgefahren | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion or sodium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2024) |
Anwendungen & Verwendung
Verwenden
Palmitoyl Chloride was used as a polymeric carriers for plasmid DNA (pDNA) delivery to 293T cells.