1-Tridecanol

log Kow = 5.82

8.52

0.846 at 68 °F (USCG, 1999) - Less dense than water; will float

VAPOR DENSITY: 6.9 (AIR= 1) /COMMERCIAL MIXTURE/

0.8223 at 31 °C/4 °C

Relative density (water = 1): 0.8

WATER WHITE LIQ

Crystals from alcohol

INSOL IN WATER; SOL IN ALCOHOL & IN ETHER /1-TRIDECANOL/

Sol in ethanol, ether

Solubility in water, g/100ml at 20 °C: 0.01 (very poor)

250 °F (USCG, 1999)

121 °C

250 °F (121 °C) (Open cup)

121 °C o.c. (mixed isomers)

525 °F at 760 mmHg (USCG, 1999)

152 °C at 14 mm Hg

155.00 to 156.00 °C. @ 15.00 mm Hg

274 °C

32.5 °C

Heat Fusion at Melting point = 4.5120X10+7 J/kmol (for the beta form)

32.00 to 33.00 °C. @ 760.00 mm Hg

30-32 °C

6.9 (Air = 1)

Relative vapor density (air = 1): 6.9

3.62 mmHg at 260 °F (USCG, 1999)

0.000436 [mmHg]

4.36X10-4 mm Hg at 25 °C

Tridecanol is an oily liquid; colorless; mild, pleasant odor. Floats on water. (USCG, 1999)

Liquid

Colorless liquid or solid; [ICSC] White solid; [MSDSonline]

Colorless liquid with a pleasant odor; [HSDB]

Solid

COLOURLESS OILY LIQUID OR CRYSTALS.

This chemical does not meet GHS hazard criteria for 3.1% (75 of 2412) of reports.

Danger

H315 (13.3%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (19.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (12.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H400 (72.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410 (64.5%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2412 reports by companies from 24 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 75 of 2412 reports by companies.；There are 23 notifications provided by 2337 of 2412 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: 1-Tridecanol

Chemical: Alcohols, C12-14

1-Tridecanol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Tridecanol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 01-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17453；Status: Active Update: 30-05-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/17503

Status: Active Update: 09-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/17532

1-Tridecanol: Does not have an individual approval but may be used under an appropriate group standard

IMAP assessments - Alcohols, C12-14: Human health tier I assessment

IMAP assessments - 1-Tridecanol: Human health tier I assessment

Combustible. (USCG, 1999)

Combustible.

MODERATE TO SLIGHT, WHEN EXPOSED TO HEAT OR FLAME

Combustible liquid when exposed to heat or flame.

A skin and eye irritant; [ICSC] A mild skin irritant, based on animal studies; [MSDSonline] See 1-Decanol.

A severe eye irritant; [CHRIS] Causes CNS depression in animal experiments; [RTECS] An irritant; [MSDSonline]

TRIDECANOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials.

1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur.

0 - Materials that in themselves are normally stable, even under fire conditions.

Extinguish with dry chemical or alcohol foam. Water may be ineffective on fire. Cool exposed containers with water. (USCG, 1999)

Use water spray, powder, alcohol-resistant foam, carbon dioxide.

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

MIST, SPRAY, DRY CHEMICAL, FOAM

To fight fire use mist, spray, dry chemical, foam.

Alc foam, dry chem, water fog. ...Water may cause frothing. /Mixed isomers/

AEROBIC: 1-Tridecanol, present at 100 mg/L, reached 100% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(1). The zero order and first order biodegradation rates of 1-tridecanol in activated sludge were 1.04X10-2 ppm/hr and 5.2X10-3 1/hr, respectively(2). Using this first order degradation rate, the half-life of 1-tridecanol can be calculated as 5.6 days(SRC).

If in liquid state: collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent and remove to safe place. If in solid state: sweep spilled substance in sealable container, carefully collect remainder then remove to safe place.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. If liquid: collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. If solid: sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 35,000(SRC), determined from a log Kow of 5.82(2) and a regression-derived equation(3), indicates that 1-tridecanol is expected to be immobile in soil(SRC). Volatilization of 1-tridecanol from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.3X10-4 atm-cu m/mole(SRC), using a fragment constant estimation method(4). However, adsorption to soil is expected to attenuate volatilization(SRC). 1-Tridecanol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 4.36X10-4 mm Hg(5). A biodegradation half life of 5.6 days(SRC) can be calculated, using a first order degradation rate of 5.2X10-3 1/hr(6), suggesting that biodegradation may be an important environmental fate process in soil(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 35,000(SRC), determined from a log Kow of 5.82(2) and a regression-derived equation(3), indicates that 1-tridecanol is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 1.3X10-4 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 14 hours and 8.5 days, respectively(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 16 years if adsorption is considered(5). According to a classification scheme(6), an estimated BCF of 600(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is high(SRC). A biodegradation half-life of 5.6 days(SRC) can be calculated, using a first order degradation rate of 5.2X10-3 1/hr(8), suggesting that biodegradation may be an important environmental fate process in water(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1-tridecanol, which has a vapor pressure of 4.36X10-4 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1-tridecanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 20 hours(SRC), calculated from its rate constant of 1.96X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).

/AQUATIC SPECIES/ The general anesthetic potency of several members of the homologous series of saturated aliphatic alcohols, including 1-tridecanol, was determined in tadpoles, using the loss of righting reflex as the criterion of anesthesia. 1-Tridecanol was found to be a partial anesthetic.

Redness.

Redness. Pain.

The Koc of 1-tridecanol is estimated as 35,000(SRC), using a log Kow of 5.82(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1-tridecanol is expected to be immobile in soil.

Chemical: 1-Tridecanol

Chemical: Alcohols, C12-14

1-Tridecanol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Tridecanol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 01-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17453；Status: Active Update: 30-05-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/17503

Status: Active Update: 09-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/17532

1-Tridecanol: Does not have an individual approval but may be used under an appropriate group standard

... Maximum permeation of melatonin (MT) was observed when fatty alcohol carbon chain length was 10. As the level of unsaturation increased from one to two double bonds, there was an increase in the permeation of MT both in porcine and human skin. However, a decrease in the permeation was observed with three double bonds. Regression analysis ... showed a significant positive correlation between porcine and human skin for saturated fatty alcohols (r(2)=0.8868, P=0.0005).

... The flux of melatonin across hairless rat skin was dependent on the carbon chain length of the fatty alcohols, with decanol showing the maximum permeation of melatonin. All fatty alcohols increased the transepidermal water loss (TEWL) and skin blood flow significantly compared with the vehicle. The fatty alcohols (decanol, undecanol and lauryl alcohol), which showed greater permeation of melatonin, also produced greater TEWL, skin blood flow and erythema. Tridecanol and myristyl alcohol showed lower permeation enhancement effect but caused greater skin irritation.

Used as a lubricant, antifoam agent, and chemical intermediate for detergents and other products; [HSDB]

Used as intermediate for plasticizers and other compounds; [HSDB]

CHEM INT FOR DITRIDECYL PHTHALATE PLASTICIZER; FOR ISODECYL TRIDECYL PHTHALATE PLASTICIZER; FOR DITRIDECYL MALEATE; FOR ETHOXYLATED TRIDECYL ALCOHOL; FOR ALKOXYLATED TRIDECYL ALCOHOL; FOR TRIDECYL PHOSPHITE; FOR TRIDECYL GLYCERYL ESTER SULFONATE; FOR TRIDECYL SULFATE SODIUM SALT; FOR TRIDECYL THIOGLYCOLATE; FOR DITRIDECYL SULFOSUCCINATE, SODIUM SALT; FOR TRIDECYL 3-MERCAPTOPROPIONATE

Esters for synthetic lubricants; detergents; antifoam agent; in other tridecyl compounds; perfumery /commercial mixt of isomers/

Chemical intermediate for detergents-eg, its ethoxylate (as mixture)

(1972) No Data

(1975) No Data

(1972) No Data

(1975) No Data

2023: 75,000,000 - <150,000,000 lb；2022: 25,000,000 - <75,000,000 lb；2021: <75,000 lb；2020: <75,000 lb

(1972) 8.8X10+9 GRAMS

(1974) 9.2X10+9 GRAMS

(1990) >1 million-10 million pounds

(1994) >10 thousand-500 thousand pounds

(1998) >10 million-50 million pounds

OXO REACTION OF CARBON MONOXIDE AND HYDROGEN WITH PROPYLENE TETRAMER, FOLLOWED BY HYDROGENATION OF THE RESULTING ALDEHYDE

Oxo process from C15 hydrocarbons.

Reaction of C11-C14 linear internal olefins with synth gas over a modified cobalt catalyst (modified oxo process) produces a mixt of n- & iso- alcohols (n-isomer predominates); reaction of olefins with synth gas followed by hydrogenation makes branched & linear primary alcohols.

Tridecyl alcohol is produced from tetrapropylene by the oxo process for use only as a processing aid in polyvinyl chloride resins.

Fragrance Ingredients

Cosmetics -> Viscosity controlling; Emollient; Refatting; Emulsion stabilizing

Petrochemical Manufacturing

1-Tridecanol: ACTIVE

/Tridecyl alcohol is/ a commercial mixture of isomers.