HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1H-Imidazol-2-amin
1H-IMIDAZOL-2-AMINE · 2-AMINOIMIDAZOLE · 2-Amino-1H-Imidazole · 2-aminoIMIDAZOLE:1h-imidazol-2-amine · 2-Aminoimidazole（2-Aminoimidazole hemisulfate）
Identifikatoren & physikalische Daten
| CAS No. | 7720-39-0 |
|---|---|
| Summenformel | C3H5N3 |
| Durchschnittliche Molmasse | 83,09 g/mol |
| Monoisotopische Masse | 83,04834716 g/mol |
| SMILES | Nc1ncc[nH]1 |
| InChIKey | DEPDDPLQZYCHOH-UHFFFAOYSA-N |
| PubChem CID | 82140 |
| ChEMBL | CHEMBL291627 |
| EC No. | 231-751-4 |
| DTXSID | DTXSID60227953 |
| Lokaler Name | 1H-Imidazol-2-amin |
Chemische & physikalische Eigenschaften
| XLogP | -0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 54,7 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 6 |
| Formalladung | 0 |
| Komplexität | 45,3 |
| Siedepunkt | 313.1±25.0 °C(Predicted) |
| Dichte | 1.313±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pKa (Säurekonstante) | 15.06±0.10(Predicted) |
| Aggregatzustand | solid |
| Farbe | Brown |
| InChI | 1S/C3H5N3/c4-3-5-1-2-6-3/h1-2H,(H3,4,5,6) |
| InChIKey | DEPDDPLQZYCHOH-UHFFFAOYSA-N |
| SMILES | Nc1ncc[nH]1 |
| CAS Datenbank | 7720-39-0(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | WGK 3 |
| Zollcode | 2933299090 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-37/39 |
| Lagerklasse | 10 - Combustible liquids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM.