2,8-Dibromodibenzofuran｜Huagongshe

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HCID 82290Erstellt: 27. Oktober 2026

2,8-Dibromodibenzofuran

2,8-dibromo- · 8-DIBROMODIBENZOFURAN · 2,8-Dibromodibenzofura · 2,8-dibrimodibenzofuran · 2,8-Dibrom-dibenzofuran · 2,8-Dibromodibenzofuran · 2,8-dibroMo dibeozofuran · Dibenzofuran, 2,8-dibromo-

https://huagongshe.com/de/chemical/82290

Molekülstruktur von 2,8-Dibromodibenzofuran

Identifikatoren & physikalische Daten

CAS No.	10016-52-1
Summenformel	C12H6Br2O
Durchschnittliche Molmasse	325,98 g/mol
Monoisotopische Masse	323,87853901 g/mol
SMILES	Brc1ccc2oc3ccc(Br)cc3c2c1
InChIKey	UFCZRCPQBWIXTR-UHFFFAOYSA-N
PubChem CID	82290
EC No.	634-508-4
DTXSID	DTXSID40142993

Chemische & physikalische Eigenschaften

XLogP	5,8
Polarare Oberfläche (TPSA)	13,1
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	1
Frei drehbare Bindungen	0
Schwere Atome	15
Formalladung	0
Komplexität	222
Collision Cross Section	148.4 Å² [M]+ [CCS Type: TIMS, Method: calibration with PAHs]
Schmelzpunkt	226℃
Siedepunkt	396℃
Dichte	1.886
Flammpunkt	193℃
Lagerbedingungen	Sealed in dry,Room Temperature
Aggregatzustand	powder to crystal
Farbe	White to Light yellow
InChI	InChI=1S/C12H6Br2O/c13-7-1-3-11-9(5-7)10-6-8(14)2-4-12(10)15-11/h1-6H
InChIKey	UFCZRCPQBWIXTR-UHFFFAOYSA-N
SMILES	O1C2=CC=C(Br)C=C2C2=CC(Br)=CC=C12

Sicherheit & Vorschriften

GHS-Einstufung	DangerH301 (97.5%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P264+P265, P270, P273, P280, P301+P316, P305+P351+P338, P321, P330, P337+P317, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard Classes and Categories	Acute Tox. 3 (97.5%)
Treatment	EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
Gesundheitliche Auswirkungen	CDFs cause vomiting and diarrhea, anemia, more frequent lung infections, numbness and other effects on the nervous system, and mild changes in the liver. However, there were no permanent liver changes or definite liver damage found in people who ingested CDFs. (L952)
Expositionspfade	Inhalation (L952)dermal (L952)oral (L952)
Toxizitätsübersicht	Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic resoponse element) promoter region. Specifically AhR binds to the PCDF, translocates it to the nucleus and together with hydrocarbon nuclear translocator (ARNT) and xenobiotic responsive element (XRE) increases the expression of CYP1A1 and aryl hydrocarbon hydroxylase (CYP1B1). AhR signaling also increseases conversion of arachidonic acid to prostanoids via cyclooxygenase-2, alters Wnt/beta-catenin signaling downregulating Sox9 and alters signaling by receptors for inflammatory cytokines. AhR signalling also alters proteasomal degradation of steroid hormone receptors, alters cellular UVB stress response and changes the differentiation of certain T-cell subsets. The resulting AhR mediated activation and alteration leads to body weight loss, cancer and thymic atrophy (characteristic of immune and endocrine disruption) which are common toxic responses to PCDFs and related toxic halogenated aryl hydrocarbons.