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N-Acetyl-α-D-glucosamin
GLCNAC · NAG · 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSE · AcetylDglucosamine · N-Acetyl-a-D-glucosamine · alpha-N-Acetylglucosamine · N-Acetyl-alpha-D-glucosamine · Acetyl chitin NAcetylGlucosamine
Identifikatoren & physikalische Daten
| CAS No. | 10036-64-3 |
|---|---|
| Summenformel | C8H15NO6 |
| Durchschnittliche Molmasse | 221,21 g/mol |
| Monoisotopische Masse | 221,0899372 g/mol |
| SMILES | CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O |
| InChIKey | OVRNDRQMDRJTHS-PVFLNQBWSA-N |
| PubChem CID | 82313 |
| ChEMBL | CHEMBL1234669 |
| ChEBI | CHEBI:44278 |
| EC No. | 233-115-1 |
| DTXSID | DTXSID20905442 |
| Lokaler Name | N-Acetyl-α-D-glucosamin |
Chemische & physikalische Eigenschaften
| XLogP | -1,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 119 |
| H-Brücken-Donoren | 5 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 15 |
| Formalladung | 0 |
| Komplexität | 235 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Kosmetika | Skin conditioning |
| SpringerMaterials Properties | 15N nuclear magnetic resonance spectrum |
| Schmelzpunkt | 211 °C |
| Siedepunkt | 595.4±50.0 °C(Predicted) |
| Dichte | 1.50 |
| Lagerbedingungen | Refrigerator (+4°C) |
| pKa (Säurekonstante) | 12.04±0.70(Predicted) |
| Aggregatzustand | powder |
| Farbe | White |
| Kosmetik-Inhaltsstoffe Funktionen | SKIN CONDITIONING |
| InChI | InChI=1/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8+/s3 |
| InChIKey | OVRNDRQMDRJTHS-UWNFICOENA-N |
| SMILES | N([C@H]1[C@H](O[C@H](CO)[C@@H](O)[C@@H]1O)O)C(=O)C |&1:1,2,4,7,9,r| |
| LogP (Verteilungskoeffizient) | -2.314 (est) |
| CAS Datenbank | 10036-64-3(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (44 of 44) of all reports.Not ClassifiedAggregated GHS information provided per 44 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | .alpha.-D-Glucopyranose, 2-(acetylamino)-2-deoxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Hazard Classes and Categories | Not Classified |
| Zollcode | 29329900 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 24/25 |
Anwendungen & Verwendung
Beschreibung
N-Acetyl-α-D-glucosamine is a low energy, vivo animal, chemical biology, expressed, oligosaccharides, acceptor. It is an acetylated amino sugar that can be found in the cell membrane surface of bacteria and is also a protein target for acetylation.
Verwenden
N-Acetyl-α-D-glucosamine has been shown to be involved in protein synthesis and growth factor activity. It has been used as a substrate for the production of monoclonal antibodies and has been shown to have stereoselective effects on the antibody response.