2-Ethylhexylsalicylat

2-Ethylhexyl salicylate

HCID 8364

Grundinformationen

CAS
118-60-5
Standard-SMILES
CCCCC(CC)COC(=O)c1ccccc1O
InChIKey
FMRHJJZUHUTGKE-UHFFFAOYSA-N
Summenformel
C15H22O3
Durchschnittliche Molmasse
250,33 g/mol
Monoisotopische Masse
250,15689456

Namen und Bezeichner

Bevorzugter Name
2-Ethylhexyl salicylate
IUPAC
2-ethylhexyl 2-hydroxybenzoate
Lokaler Name
2-Ethylhexylsalicylat
Englischer Name
2-Ethylhexyl salicylate
Summenformel
C15H22O3
Molmasse
250.33

Namen und Synonyme

2-ETHYLHEXYL SALICYLATEOctisalate118-60-52-Ethylhexyl 2-hydroxybenzoateBenzoic acid, 2-hydroxy-, 2-ethylhexyl esterEscalolSalicylic Acid 2-Ethylhexyl EsterOctisalatoDTXSID7040734NSC-461514X49Y0596WDTXCID5020734
Weitere Namen anzeigen
Octyl salicylateOCTISALATE,USPNeo Heliopan OSSALICYLIC ACID OCTYL ESTERSALICYLIC ACID-2-ETHYL-1-HEXYL ESTERWMOusafdo-11
OCTYLSALICYLATEoctisalatumTanning OilRefChem:856053Arizona Sun Tanning Oil SPF 3204-263-4Ethylhexyl salicylateSunarome WMO

Datenbank-Bezeichner

CAS
118-60-5
PubChem CID
8364
DTXSID
DTXSID7040734
ChEMBL
CHEMBL1329203
ChEBI
CHEBI:88639
UNII
4X49Y0596W
EC Number
204-263-4
Nikkaji
J82.395C

Eigenschaften

Berechnete Struktureigenschaften

XLogP
5,7
Polarare Oberfläche (TPSA)
46,5 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
8
Schwere Atome
18

Experimentelle und physikochemische Eigenschaften

Physical DescriptionLiquid
Kovats Retention Index · 2 Einträge

1769

1816.7;1805;1814;1807

Collision Cross Section · 1 Eintrag

151.39 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards];154.54 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards];158.92 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards];161.26 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Physikochemische Eigenschaften

Siedepunkt
189 · 189-190 °C/21 mmHg (lit.)
Dichte
1.014 g/mL · 1.014 g/mL at 25 °C (lit.)
Dampfdruck
0.018 Pa · 0.018Pa at 20℃
Brechungsindex
20 · n20/D 1.502(lit.)
Flammpunkt
230 °F · >230 °F
storage temp.
Refrigerator

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.8% (14 of 1669) of reports.

Warning

H315 (84.7%): Causes skin irritation [Warning Skin corrosion/irritation];H410 (14.4%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P264, P273, P280, P302+P352, P321, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1669 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 14 of 1669 reports by companies.;There are 8 notifications provided by 1655 of 1669 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester

Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 18-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14203

Ethyl hexyl salicylate: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (84.7%);Aquatic Chronic 1 (14.4%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Ethylhexyl Salicylate...

Safe for use in cosmetics, with qualifications

Regulatorische Informationen

Regulatory Information · 4 Einträge

Chemical: Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester

Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 18-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14203

Ethyl hexyl salicylate: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
-
tsca
TSCA listed
hs_code
2918230000
RTECS-Nr.
VO3150000
risk_code
36/37/38
Toxizität
LD50 intraperitoneal in mouse: 200mg/kg

Chemie und Industrie

Pharmakologische Informationen

Protein BindingIntended for local use only, no systemic absorption.
PharmacodynamicsData not found.
Mechanism of ActionChemical sunscreen, it acts through absorption of UVB light and not UVA.
Biological Half-LifeIntended for local use only, no systemic absorption.
Metabolism/MetabolitesIntended for local use only, no systemic absorption.
MeSH Pharmacological ClassificationChemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.

Verwendung und Herstellung

UsesCIR ingredient: Ethylhexyl Salicylate
U.S. Production2023: 37,038 lb;2022: 52,911 lb;2021: 63,660 lb;2020: 40,124 lb
Consumer UsesFragrance
Industry UsesFragrance
Household ProductsInformation on 101 consumer products that contain Octisalate in the following categories is provided:;• Personal Care;• Pet Care
Use Classification · 2 Einträge

Fragrance Ingredients

Cosmetics -> Uv absorber; Uv filter

Anwendungen

OccurrenceHas apparently not been reported to occur in nature.

Verwenden2-ethylhexyl salicylate is also known as ethylhexyl salicylate and octyl salicylate. It is a uVB absorber.

Darstellung

synthetischeFrom 2-ethylhexanol and salicylic acid by azeotropic-type esterification (Arctander, 1969).

Anbieter100 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]

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