2-Imidazolidon

NEEDLES FROM CHLOROFORM

WHITE LUMPY POWDER

VERY SOL IN WATER & IN HOT ALC; DIFFICULTLY SOL IN ETHER

SLIGHTLY SOL IN CHLOROFORM

CBI; Liquid

White odorless solid; [Hawley] Light yellow crystals; [Aldrich MSDS]

This chemical does not meet GHS hazard criteria for 0.1% (1 of 857) of reports.

Warning

H319 (99.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H361 (13%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]；H373 (24.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P203, P260, P264+P265, P280, P305+P351+P338, P318, P319, P337+P317, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 857 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 857 reports by companies.；There are 13 notifications provided by 856 of 857 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: 2-Imidazolidinone

Commission Regulation No 844/2012

2-Imidazolidinone is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Imidazolidinone are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 15-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12504

Ethylene urea: Does not have an individual approval but may be used under an appropriate group standard

MANCOZEB, 2-IMIDAZOLINE & ETHYLENEUREA RESIDUES WERE DETERMINED IN TOMATO & POTATO CROPS AFTER FIELD TREATMENT WITH MANCOZEB. LOW LEVELS (LESS THAN 0.04 PPM) OF ETHYLENEUREA WERE PRESENT IN TOMATOES UP TO 28 DAYS AFTER SPRAYING. ETHYLENEUREA WAS NOT DETECTABLE IN POTATO TUBERS.

ETHYLENEUREA INDUCED CANCER IN RATS & MICE WHEN ADDED TO FOOD WITH SODIUM NITRITE.

EFFECTS OF 0.125-2.0 MG/ML ETHYLENEUREA IN VITRO ON XENOPUS LAEVIS SPERMATOZOA PRODUCED HIGH YIELDS OF ABNORMAL EMBRYO.

IN SALMONELLA TYPHIMURIUM HIS G-46, ETHYLENEUREA SHOWED RELATIVE MUTAGENIC ACTIVITY OF 0.9, WITH ACTIVITY DUE TO SPONTANEOUS REVERSIONS BEING 1.0.

SINGLE DOSE (480 MG/KG INTRAGASTRICALLY) OF ETHYLENEUREA WAS ADMINISTERED TO FEMALE WISTAR RATS ON DAY 12 OR 13 OF GESTATION. IT WAS NEITHER MATERNALLY TOXIC NOR TERATOGENIC (ALTHOUGH MINOR SKELETAL CHANGES WERE PRESENT).

Chemical: 2-Imidazolidinone

Commission Regulation No 844/2012

2-Imidazolidinone is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Imidazolidinone are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 15-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12504

Ethylene urea: Does not have an individual approval but may be used under an appropriate group standard

METABOLISM STUDY IN RATS INDICATES THAT DEHYDROGENATION OF (14)C-ETHYLENEUREA IS EXTENSIVE YIELDING IMIDAZOLE AS MAJOR URINARY METABOLITE. COMPOUND WAS ADMINISTRATED ORALLY.

IN MICE TREATED ORALLY WITH (14)C-LABELED ETHYLENETHIOUREA, ETHYLENEBISDIISOTHIOCYANATO SULFIDE, MANEB, & ZINEB, ETHYLENEUREA WAS A URINARY METABOLITE.

Used to make high polymers, plasticizers, lacquers, adhesives, and textile and leather finishing agents; Also used as an insecticide; [HSDB]

Farming (Pesticides) [Category: Industry]

MFR HIGH POLYMERS; IN FORMULATION OF PLASTICIZERS, LACQUERS, & ADHESIVES; INSECTICIDE

CHEM INT FOR TEXTILE & LEATHER FINISHING AGENTS

(1975) No Data

(1977) No Data

(1975) No Data

(1977) No Data

2023: 250,000 - <400,000 lb；2022: 250,000 - <400,000 lb；2021: 250,000 - <400,000 lb；2020: 400,000 - <550,000 lb

(1975) No Data

(1977) No Data

REACTION OF ETHYLENEDIAMINE AND UREA

PREPD FROM ETHYLENEDIAMINE & CARBON DIOXIDE UNDER INFLUENCE OF HEAT & PRESSURE...

Fragrance Ingredients

Environmental transformation -> Pesticide transformation products (metabolite, successor)

All Other Chemical Product and Preparation Manufacturing；All Other Basic Organic Chemical Manufacturing；Textiles, apparel, and leather manufacturing

2-Imidazolidinone: ACTIVE